6EZN


Conserved Protein Domain Family
Ost4

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pfam10215: Ost4 
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Oligosaccaryltransferase
Ost4 is a very short, approximately 30 residues, enzyme found from fungi to vertebrates. It is a member of the ER oligosaccaryltansferase complex, EC 2.4.1.119, that catalyzes the asparagine-linked glycosylation of proteins. It appears to be an integral membrane protein that mediates the en bloc transfer of a preassembled high-mannose oligosaccharide onto asparagine residues of nascent polypeptides as they enter the lumen of the rough endoplasmic reticulum (RER).
Statistics
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PSSM-Id: 431142
Aligned: 48 rows
Threshold Bit Score: 32.9184
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6EZN_D         1 MISDEQLNSLAITFGIVMMTLIVIYHAVDSTMS 33  Saccharomyces cerevisiae S288C
B0BLS0         1 MITDVQLAIFANMLGVSLFLLVVLYHYVAVNNP 33  Norway rat
XP_011150984   1 MITDVQLAVFCNILGVTLFFLVFLFHYISANYS 33 
XP_002428412   1 MITDIQLAIFANALGITLFLLVVIYHYVAANYS 33 
CCD80633       1 MITDVQLTVFANLAGSVLFLLVVLYHYVIVNQK 33 
Q6BEV3         1 MISDVQLGIAANILGIAMLMLVVLFHYLNANQK 33  Caenorhabditis elegans
XP_019079527   1 MIDDQDLGFFANFLGIFIFVLVIAYHYVIADPK 33 
XP_014621343   1 MIDDETLGAIANFLGIFIFALVIAYHLVTADPK 33 
Q8L986         1 MFDDQDLGFFANFLGIFIFIMVIAYHFVVAEPK 33  thale cress
Q54V54         1 MITDTQLTLLSNTLGATIFLLIVYYHYVATKTV 33  Dictyostelium discoideum
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