3RAY


Conserved Protein Domain Family
PR-SET_PRDM11
?
cd19195: PR-SET_PRDM11 
PR-SET domain found in PR domain zinc finger protein 11 (PRDM11) and similar proteins
PRDM11 (also termed PR domain-containing protein 11) may be involved in transcription regulation.
Links
?
Statistics
?
PSSM-Id: 380972
Aligned: 6 rows
Threshold Bit Score: 247.078
Created: 11-Jun-2018
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
 
putative activeputative SAMcatalytic
Conserved site includes 19 residues -Click on image for an interactive view with Cn3D
Feature 1:putative active site [active site]
Evidence:
  • Comment:Based on the structure evidence that Mus musculus PRDM9 (4C1Q) binds H3k4me2 and S-adenosylhomocysteine (AdoHcy) through its PR-SET domain.
Download Cn3D for Viewing 3D StructureScroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1                         ###                 #            #####         #            ####
3RAY_A         66 AALTIPQGMEVVKDTsGESDVRCVNevIPKGHIFGPYEGQISTQDksaGFFSWLIVDKNNRYKSIDGSDEtkANWMRYVV 145  human
Q9NQV5        143 AALTIPQGMEVVKDTsGESDVRCVNevIPKGHIFGPYEGQISTQDksaGFFSWLIVDKNNRYKSIDGSDEtkANWMRYVV 222  human
OCT83676      108 AALTVPCGIEVVKDMsGESEVRCVNelIPKGHMFGPYQGQICSQDkssGFFSWLIVDNNNRYKSIDGTDEayANWMRYVV 187  African clawe...
XP_005986982  102 AALTAPPGIHIVKGSnGEIDVECVDevVQKGRIFGPYEGQITTQDksaGFFSWLIVDKNNRYKSIDGTDEtkANWMRYVV 181  coelacanth
XP_007903029   61 AALSVPAGVAVVKEPgGEIDVRCLDvaIPRGRIFGPYEGEVCQTDqssGFFSWLILGKNNTYKSIDGTDEtkANWMRYVI 140  elephant shark
XP_693848      82 AALTAPSGIEVRRNG-DKVDVYCMDekIPKGALFGPYKGQIMASDkpsGPYSWMIVDKDSKYKFIDGSDEatANWMRFIH 160  zebrafish

Feature 1         # #        ##                       #          
3RAY_A        146 ISREEREQNLLAFQHSERIYFRACRDIRPGEWLRVWYSEDYMKRLHS 192  human
Q9NQV5        223 ISREEREQNLLAFQHSERIYFRACRDIRPGEWLRVWYSEDYMKRLHS 269  human
OCT83676      188 ISREEREQNLMAFQHSEKIYFRACRDIQPGEKLRVWYSEDYMKRLHS 234  African clawed frog
XP_005986982  182 ISRDEREQNLLAFQHSEKIYFRASRNLHPGERLRVWYSDEYMKRLHS 228  coelacanth
XP_007903029  141 ISREENEQNLMAFQHGEQIYFRVCRDVDPGERLRVWYSEDYMKRLHA 187  elephant shark
XP_693848     161 ITSDESEQNLSAFQHGDQIYFRVCHRLKVGEKLGVWYSSEYMKRLQS 207  zebrafish

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap