Conserved Protein Domain Family
FIT1_2
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pfam17357: FIT1_2 
Facilitor Of iron transport 1 and 2
Fit proteins (facilitor of iron transport) found on Saccharomyces cerevisiae cell wall are mannoproteins implicated in the siderophore-iron bound transport. This domain family can be found in FIT1 and FIT2 proteins in Saccharomycetaceae. The FIT1-3 cell wall mannoproteins are attached to the beta-glucan layer through a GPI (glycosylphosphatidylinoisitol) anchor. They are very rich in serine and threonine residues (40-50 % serine and threonine) and bear several short repeat of 6-7 amino acids sequence. The exact domain function is unknown.
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Statistics
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PSSM-Id: 375150
Aligned: 4 rows
Threshold Bit Score: 40.4653
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q6CY00    50 EYLTSIVVTRGDTVYTKVITESSAAATEETTAaaeETTAAAETTSAAAETTTAAPaEETSSAQESETITLTLSKNGHW-- 127 Kluyveromyces lactis
Q6CXZ8    25 STIKTIVATNGDHVYTKVVTDSAAPVYTESTT---VTTTITNNGASYVKTLTIAP-QTTIGSSTTSKITITNSDNGAT-- 98  Kluyveromyces lactis
AQZ16423  25 KTTKVITATNGDNVYTKTVTDDADPVLSHSTT---RTVTVSNSAATYTKVITEGP-NV--ESSTTKTLTLTNSVGSSTdl 98 
CAR23767  25 MTTKTITATNGSNVYTKVVTDTADPIISQSTT---RTVTVKNSDATYTKVVTEGP-DTTSLSSTTKTITATNQSGS---- 96 

Q6CY00   128 FTKTVTQAVGYV 139 Kluyveromyces lactis
Q6CXZ8    99 YTKTNVVAISSS 110 Kluyveromyces lactis
AQZ16423  99 YTKTVAEAIESS 110
CAR23767  97 YTKTVTAAVTSS 108
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