?cl24019: CSN8_PSD8_EIF3K Superfamily (this model, PSSM-Id:420155 is obsolete and has been replaced by 474128)
CSN8/PSMD8/EIF3K family This domain is conserved from plants to humans. It is a signature protein motif found in components of CSN (COP9 signalosome) where it functions as a structural scaffold for subunit-subunit interactions within the complex and is a key regulator of photomorphogenic development. It is found in Eukaryotic translation initiation factor 3 subunit K, a component of the eukaryotic translation initiation factor 3 (eIF-3) complex required for the initiation of protein synthesis. It is also found in 26S proteasome non-ATPase regulatory subunit 8 (PSMD8), a regulatory subunit of the 26S proteasome. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",