Conserved Protein Domain Family
SSXT

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pfam05030: SSXT 
SSXT protein (N-terminal region)
The SSXT or SS18 protein is involved in synovial sarcoma in humans. A SYT-SSX fusion gene resulting from the chromosomal translocation t(X;18) (p11;q11) is characteriztic of synovial sarcomas. This translocation fuses the SSXT (SYT) gene from chromosome 18 to either of two homologous genes at Xp11, SSX1 or SSX2.
Statistics
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PSSM-Id: 428268
Aligned: 22 rows
Threshold Bit Score: 58.0535
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
TDH66555      33 KQIGTEQIQAMLDENSSLIVEIIELNTQikhgkgtaqlGeFTEKLDKKRKNLNKNLMTLAKWADESSETSP 103
EGT48455      14 AADQQSTVQKLLDENSRLIDIIREYQNQ----------G-RADEAMKHQQLLHRNLMHLSNLADPFLLSQL 73 
NP_001138658  14 AEVNQETIQRLLEENDQLIRCIVEYQNK----------G-RANECVQYQHVLHRNLIYLATIADANPTSAS 73 
XP_003229053  14 AEVNQETLRRLMDENDQLIRCIVEYQNK----------G-RAAECMQLQHTLHRNLIYLATIADASASSNA 73 
Q567E9        14 AQINQETIQRLLDENDQLVRCISEYQQK----------G-RATECVQYQQILHRNIVYLGTIADASTEIQP 73  zebrafish
OCA36688      14 GQVGEDTVQRLLEENDQLIRCIVEYQNK----------G-RATECSQYQQILHRNLIYLASIADSGATNtv 73 
XP_015784271  13 GPTNSAQIQKMLDENSNLIQAVMEAQNK----------G-EAQKSVHLISTIHRNLLYLGSLSESNPNLAQ 72 
XP_001631281  11 PEPSSQSVQELLDENTQLIQAIVDYQNK----------G-KAYESTQYQQLLHRNLVYLATLADSNQTGQP 70 
Q8BKL1        14 GEITPAAIQKMLDENNHLIQCIMDYQNK----------G-KASECSQYQQILHTNLVYLATIADSNQNMQS 73  house mouse
XP_002129850  15 SAVTQETIQKMLDENSRLIQCIVDEQQN----------G-RMQDCSRYQQILHRNLVWLATVADSNQSNGQ 74 
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