6ZPG


Conserved Protein Domain Family
KBP_C

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pfam12309: KBP_C 
KIF-1 binding protein C terminal
This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 365 and 621 amino acids in length. There is a conserved LLP sequence motif. KBP is a binding partner for KIF1Balpha that is a regulator of its transport function and thus represents a type of kinesin interacting protein.
Statistics
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PSSM-Id: 463528
Aligned: 28 rows
Threshold Bit Score: 298.427
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6ZPG_A       247 IEWAINAATLSQFYINKLCFMEARHCLSAANVIFGQ--TGki-------------------------------------- 286
EKC21399     227 LDWAINAATLSQYFVTKDEYPQARHCLACAEVIFEEiqFS---------------------------------------- 266
XP_009018983 230 LEWAMNAATLSQYYITIYDFTTARYCLASAETILKE--FGek-------------------------------------- 269
CDS36870     272 KDWANNTAALSEYYVETEEFGKALECLMTARTVVC--------------------------------------------- 306
2_pfamImport   1 HEWVRNALKLVEFYLNTDNLIDAAACLQGSEYMLLQrr------------------------------------------ 38 
XP_019852056 227 IEWSLNAATISQYYINVSNYPQARHCLAAASVVLRS--YSee-------------------------------------- 266
EDV21336     226 LDWAINCATLSDYYTSKRNWNLARHCLACASAVIGEdcrvpdsg------------------------------------ 269
XP_003207938 203 VEWALNAATLSQYYLSKQCFMESRHCLAAASVIFSQ--AGqv-------------------------------------- 242
CBJ28687     358 GEWSRNACFLADYYSGLGRFTGAGRCLLAAQAVLQPegSAaavptggkdnaslpppppargkdegeekgedggnaksggd 437
XP_014340477 245 VEWAINAAALSQYYITEQRYMEARHCLAAANVIFSH--AEei-------------------------------------- 284 coelacanth
6ZPG_A       287 --------sATEDTPEAEge-------------vpELYHQRK--------------GEIARCWIKYCLTLMQNAQLSm-- 329
EKC21399     267 ---------ENENVSEDEk----------------EKVQQGK--------------ADIQRCWAKYGLALLEFSKDRl-- 305
XP_009018983 270 --------pASLKVPVTNadgqd-------ainvlERLPKAW--------------ADLFRCWSKYSLVLLEHSRDSl-- 318
CDS36870     307 -----------------------------------ESFQNGDssglghnlngtklwADISWLTSEYSLGLLEGGSKVvlg 351
2_pfamImport  39 --------iGGDKEEESDqfl---------------------------------ltANIYTMWGRVHETTLRLAGMRkeg 77 
XP_019852056 267 --------lGGKGEEMK------------------EKLEQSE--------------ADVSRCWIKYTISLLTHSc----- 301
EDV21336     270 --mteeelrEESQAELDEr----------------EKVYKKR--------------AEVARLWAKYALELFTESRNAven 317
XP_003207938 243 --------pSTE---DNEteq-----------dqqD-LRQRK--------------AEIARCWIKYCLNLLQSARKLl-- 283
CBJ28687     438 sggatraggGGRETEKVStanerkreeeegteeerERRREQR--------------ADVDRHMAKLYITVLQAKHLE--- 500
XP_014340477 285 --------pSETAAEENEvei-----------drhEQLSQKK--------------SEIARCWIKFCLNLLQDARKMl-- 329 coelacanth
6ZPG_A       330 --QDNIGELDLDKQSELRALRKKELDEeesirkkavqfgtgelcdaISAVE-EKVSYLrp--------------ldFEEA 392
EKC21399     306 --LKATEEDTPLDPDESEKEFEKFNLE-------------------VTSRE-EQITCKpv--------------rdFEEA 349
XP_009018983 319 --MEKSKDDEISNIQNSSAECNSKKEffn---------------leTTSAV-NQITDRrv--------------lvFDEA 366
CDS36870     352 srFTIDPELVDTSPSYGSLFNQDTTKAlqeay---------gepiqDTGLT-TMISELsim------------pkaYPAA 409
2_pfamImport  78 lyTKGTDPMLPHTCSMETTLAK------------------------LSYARqSELLEDqstpglgmrfvpphcletFDQA 133
XP_019852056 302 --TESGERGGGGGTREKVAIVHRFEPLe------------------LADVE-GQVSCDvv--------------enYQDA 346
EDV21336     318 hgAESVRELHISDNPEASRDRKnilyf---------------dgleTTSYD-ESIPDHli--------------adFDEA 367
XP_003207938 284 --EDNIGELDPDRQLELKAQRKKEEDEkengrkkavlfgtsdicdsVLAME-EKVSSVyp--------------ldFQEA 346
CBJ28687     501 --LGRGGGAGGEFCKVRTREEEEEEEGlvagfa-------slgigeLPMCDpAGVPGD------------------FESV 553
XP_014340477 330 --EDNIGELDPGRQDEMKARRKKEEEEkeegrknavlfgssdlydvILAVE-EKVSCVyp--------------ldFTEA 392 coelacanth
6ZPG_A       393 RELFLLGQHYVFEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFETDMERRCKMHKRRIAMLEPLTVD-LNPQYYLLVNR 471
EKC21399     350 RNVFLRVQTWISGAKEFYVFDGRCTDYIELVQDHSKAFKLLAFFELNLDRQCKMHKRRADMLLEVCNE-LNPQHYLLIVR 428
XP_009018983 367 KQVFLQTQSWLNSAKEFYCLDDHCSDYVDIVKDNSTLFKLLLFFEPDLTRQCKMHKRRADMLTEILHL-LNPQFYLDVCR 445
CDS36870     410 ARLFRWTCRSLSEALLYYRLDERCTEAIKLIRAHASAYGYLATFEADLPRKCCMQKRRVDLLEDLLAQ-LNPRFYMLSCR 488
2_pfamImport 134 RDVFKMGIFACTRARKMFAFDAFATQYVHLLQQESALYRQLLPFEDVHGRRVAIQRRRLALFTPLLEDaLIKRSHPGLLQ 213
XP_019852056 347 SKVFLFAEAQIKLAQKFYNLEDHATDFVSISQDHSSLYKILSFFESDLSLKCRMHKRRVDILSSLLSC-LNPQYYLVLNR 425
EDV21336     368 RKVFLTGLRWSEKAKDFFILDGHTSDHVELVQLQSRLYFILAFFEKDLERQCKMHKRRVDLLTSIEKE-LNPQFFLTVCQ 446
XP_003207938 347 REIFLVGQNYVQEAKEFFQVDGYVTDHIEIVQDHSALFKVLAFFEEDYERRCKMHKRRIDMLEPIYAD-LNPQYYLLISR 425
CBJ28687     554 RDVFKRAKSHTERALRHYVLDGFVTAHVALHQGLSRAYLYLSGFERDAKRRQAMCTRRAQALEPLLDA-LARKAYARLHK 632
XP_014340477 393 REIFLVGQNYISEAKEYFELDGHVTDHVEILRDHSALFKAVAFFEEDYERCCKMHKRRIDMLEPIYNE-LNPRFYLLICR 471 coelacanth
6ZPG_A       472 QIQFEIAHAYYDMMDLKVAIADRLR--D-PDSHIV------------KKINNLNKSALKYYQLFLDSLr----------- 525
EKC21399     429 QLIYELAEIYSGIMDIKYMILKEEG--GqPSIHAI------------KKINSLALQSIQKYQAYIDSFk----------- 483
XP_009018983 446 QLAFEIGEVFTAILDNKLALLELTGsaRmCDGHAN------------NKINILAKKSIEYFQLYLSYLk----------- 502
CDS36870     489 TIMSECAEALTALRDLNEEKMKRTTirAsPTSSLSstnivaelsklaKKVNGLGLRALEMYKRLLDSFl----------- 557
2_pfamImport 214 EIYFECAEINGDVFELKQGKDAG------------------------EKAMTYAINAIQCYQEFLLLYycstepdgasyd 269
XP_019852056 426 QLMFELGDTLNDMANNKIILASEEG--SsPSQHQI------------QKINRLLNDAIKHYGEFFSSF------------ 479
EDV21336     447 QLCFEIGETTNEMVTLKIAIGNRE---DvPSVHTV------------KKINSLIQNSVEHFNKFIGSFv----------- 500
XP_003207938 426 QLQFELADTYYEMMDLKVAIGNRL---EeLDSHTI------------KKINSLAQLAIKYYELFLDSLr----------- 479
CBJ28687     633 ELSFELGEIYQDLADIKTLRAEEKLksGgTRAPTAlas-------dlRGANKLLKSAIGFFSHFVAMYheg--------- 696
XP_014340477 472 QLQFELADTFYEMMDLKVAIATKL---DeLDSHTI------------KKINHLAQSAIRYYELFLDSLr----------- 525 coelacanth
6ZPG_A       526 ----------DPNKVFPEH----IGEDVLRPAMLAKFRVARLYGK-IITADPKKELENLATSLEHYKFIVDYCEK-HPEA 589
EKC21399     484 ----------DNKPDLPDE----YPELDTRPILVAWFCMGRLYSK-ILPLNVRERLDNIKKTEACYQYIIDYCKR-HHKA 547
XP_009018983 503 ----------KNDKTFPET----FQDDDERPALIAHFHCGRLFSK-ILTASPKENLQNTKNSLDCYNFLVEYCRK-NPSA 566
CDS36870     558 ---------tPANQREPDL----YEEEWLPHVLMAHFYSARLHSKtIIAGAPRNRVGELHLAMKAYEKMVEIADKhARSG 624
2_pfamImport 270 dhvrasvlrgGKGVQLPPGk--aLCPREFRAMLMGYFGLANACGKiLYLSDAAKIVGFWCQSLAYYEAVTELARKyASTY 347
XP_019852056 480 -------------ETQPEA-------EYLHSYLTSKLNVARLYSK-LLAGNPGEQIKNLETSIQSYKWLIEYCEShTEEI 538
EDV21336     501 ---------dRRTGKLPET----IHDDYLRPILLAKFYLARLWKK-YIAKDTKSQMEFLSKSLQCLEYIVQYADA-HSDM 565
XP_003207938 480 ----------NPDKVFPEE----LEEDVLRPAMVAKFHIARLYGK-LITSDSKKQLENMQTSLEYYMFLVDYCEK-HPDA 543
CBJ28687     697 -------dpsGGSAESPSQpakgMEPDEAVGYLQARFMRARLNGK-LRPLTSEKELHALRVSCGEFAWLSEHARGhLKSV 768
XP_014340477 526 ----------SPDKKFPEK----LESDVLRPALVAKFRIARLYGK-FITSNGRKQLDNMQKSLDYYSFVVDYCHA-NLQA 589 coelacanth
6ZPG_A       590 --------AQEIEVELELSKEMVSLLPTKMERF 614
EKC21399     548 --------AECMRAELEVCEEMVALLPLKMEKI 572
XP_009018983 567 --------AKKVKEERDACEEMVKLLPGKMDKI 591
CDS36870     625 --------YKVDMPEVEIAREMTQLLAGQIARt 649
2_pfamImport 348 yaadgnelRRSMKSELTICDEMARLLPEKIDQL 380
XP_019852056 539 --------KEVFTEELGLCKEMVALLPQKIELi 563
EDV21336     566 --------PKVFEDELVVSREMAHFLPYEISKL 590
XP_003207938 544 --------VRAVETELELSKEMVGLLPTRMERL 568
CBJ28687     769 ret--agdPGIFEQELELAEEMAQLQRRNIANL 799
XP_014340477 590 --------TRAVETELELCEEMAGLLPARMERL 614 coelacanth
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