1J6O


Conserved Protein Domain Family
TatD_DNAse

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cd01310: TatD_DNAse 
Click on image for an interactive view with Cn3D
TatD like proteins; E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity.
Statistics
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PSSM-Id: 238635
Aligned: 84 rows
Threshold Bit Score: 147.72
Created: 10-Jan-2006
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
active site
Conserved site includes 5 residues -Click on image for an interactive view with Cn3D
Feature 1:active site [active site]
Evidence:
  • Comment:active site is based on homology to other members of the amidohydrolase family

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1         # #                                                                         
1J6O_A     13 XVDTHAHLHfhqfd--ddrnaVISSFEENn-iEFVVNVGVnle--------dsKKSLDLskts--------driFCSVGV 73  Thermotoga maritima
NP_902506  59 LIDPHAHMIart-------tdDYEAMAASg-vVAVIEPAFwlgqartnvgsfvDYFSTItgferfraaqfgirhYCAIGL 130 Chromobacterium vi...
NP_484464  11 FIDPHIHMSsrt-------tdDYEKMRQSg-iVAVIEPAFwfgqprtnvgsfqDYFSSLvgwerfrasqfgikhYCTIGL 82  Nostoc sp. PCC 7120
NP_842779   3 WIDSHIHVDqykde---eksrLLKDVENSkeiQGLIAVSMnyq--------ssKEILSLakry--------sfvHPAVGF 63  Bacillus anthracis...
NP_559693   1 MFDNHVHCHefp-------rdEITQYQKDw-tLVCVSDDLes----------sKKTVELqg------------vVKCIGI 50  Pyrobaculum aeroph...
NP_147217   9 VYDMHVHLHeysd----reveEILDADKSl-vVVAVSDDLes----------aWRTLDLwhtf-------ggrvVPCLGF 66  Aeropyrum pernix
NP_341622   2 LVDSHAHIDvk--------efDMDREFVIn-eCQILIVNAgvdf------qsnLHTLELakky--------kniIPAIGF 58  Sulfolobus solfata...
P45305      2 LFDSHLHLDqls------denIQQTLAHSk-iIGMLAVSTnln--------saKKLLNLkqty-------pkklYIAAGF 59  Haemophilus influe...
B97072      2 FIDAHNHLDffeeqeklnkalDIIKNDNIi--TLGCSMDTks----------yKFTKSLalkn--------kniIPCFGI 61  Clostridium acetob...
NP_756373   2 SIDMHCHLDlyp------rpdLVAEESKRr-gTYILSVTTtpk--------awHGTSLLakes--------qriRTALGL 58  Escherichia coli C...
Feature 1                                                                              #      
1J6O_A     74 HPhdakevp--edfiehlEKFAKDEk-vVAIGETGLDFFrnis----paevQKRVFVEQIELAGkl-nlPLVVHIRda-- 143 Thermotoga maritima
NP_902506 131 NPkeannreladavldvlPRYLGKEg-vVALGEIGYDEQte---------lEDRAFRAQIELAQef-dlPIMIHTPhrdk 199 Chromobacterium vi...
NP_484464  83 NSkeannevlaeqvmellPLYACKEg-vVAIGEIGYDDMtp---------aEDKYFRLQLELARel-diLVMIHTPhrdk 151 Nostoc sp. PCC 7120
NP_842779  64 HPeqpihke--ecekiykLIEDHVEd-iVAIGEVGLPYYlrkedehiainsYISVLQRFVELASky-dlPIVLHAVye-- 137 Bacillus anthracis...
NP_559693  51 HPwqverae--pgdlnttLRLIEKWe-vPCVGEVGLDKKfvph----sydkQVEYFRAFLKLARel-dlVVNVHAPda-- 120 Pyrobaculum aeroph...
NP_147217  67 HPwnvregr--vweawevLRLAYRYg-vPCLGEVGLDRRfvdey---twrvQNEVFDAFVQLAEdm-gvMLNIHAPda-- 137 Aeropyrum pernix
NP_341622  59 HPefvkdk-----vneidKCLELTRy-gKIISEVGLDYFwikde--dlrkkQIEVLEKFLQIAEke-nkPVIIHIRgg-- 127 Sulfolobus solfata...
P45305     60 HPeqqlpsl--eeqkklfQWIDEHHssiSAIGEVGLPHYskrenpnldyvpYIELLERFILIAKkw-dlPLNLHIVhn-- 134 Haemophilus influe...
B97072     62 HPsrahe------nfknlECFDEYIresKIIGEIGLDYVwvkek--ekyphMKRVFTYFLEEAKky-nkITNIHTKga-- 130 Clostridium acetob...
NP_756373  59 HPqiahq------rshelDLFDSLLsetKYVGEIGLDGGqgfke---hwdiQLKVFRHILNSVNraggkIMTIHSRgs-- 127 Escherichia coli C...
Feature 1                            #                                                  #     
1J6O_A    144 ---ySEAYEILRteslpekRGVIHAFSsdyeWAKKFidlGFLLGIGGPVTYpkne-alrEVVKRVGleyIVLETDCPFLP 219 Thermotoga maritima
NP_902506 200 krgtRRTMDTLEacgfdpaRCVIDHNNe--eTAQEVldrGYWCAFTIYPSTkmgndrlaAIVERYGp--ERIIVDSACDW 275 Chromobacterium vi...
NP_484464 152 kagtSRSMDVCIehglkpsQVIVDHNNe--eTVKEVldrGFWAAFTIYPNTkmgnarmvEIVRQYGs--NRIIVDSSADW 227 Nostoc sp. PCC 7120
NP_842779 138 --daDVVCDLLEkhk--vsRAHFHWFKgsetTMERMmrnGYYISITPDVLHkek---irKIVSYYPleyMMVETDGPWGF 210 Bacillus anthracis...
NP_559693 121 ---wQDALEMLRrad--vdRAIIHWFTgplqLLETIkdyGYYITINPAVAIqrk---hqEVAKTADrriVLLESDGPYEY 192 Pyrobaculum aeroph...
NP_147217 138 ---wKHVAHRIGwts--raRFMYHWYTgpatLPRALpegRVWFSINSAIRVqek---svRVAREIPlrsLVVESDGPYNY 209 Aeropyrum pernix
NP_341622 128 ---mKDFLEIINsy---riRFVIHSFEgsvkIANKVieyGGLISIPPIIVRdkv---rqKVAKEIPldfILTETDSPFMG 198 Sulfolobus solfata...
P45305    135 --dvEIALELLQkhn--iqRAHFHWFKtdekSFQKFfstPYFASLTPDILWnsk---tqYVAQHLSlnrLMIETDSPWQH 207 Haemophilus influe...
B97072    131 ---eSEIYNYIKkye--lkTPIIHWYSgdkdTLKKLldyGCYFTISVDIGYskl---skEIVQLLPidkILTETDGPTSL 202 Clostridium acetob...
NP_756373 128 ---aSAVLDEIEni---dgVAILHWFTgtpkQLERAidlGCWFSVGPAMLDtik---gkALVLKIPksrILTETDGPFAK 198 Escherichia coli C...
Feature 1                                                  
1J6O_A    220 PqpfrgkrNEPKYLKYVVETISQVlgvpeakVDEATTENARRIFL 264 Thermotoga maritima
NP_902506 276 Gv------SDPLAVAKSARIMAAHglg-eaaIRQVVYHNALAVYG 313 Chromobacterium violaceum ATCC 12472
NP_484464 228 Gv------SDPLAVPKTALLMLERgis-eadVEKVCYENALSAYG 265 Nostoc sp. PCC 7120
NP_842779 211 Qeg---vmTHPGMIREVLKEISVIknvavdkVAETIYENTIQFYL 252 Bacillus anthracis str. Ames
NP_559693 193 Rgm----rLAPPVIKNTVEKLSELweapkdyVVEVVETNAKRLWR 233 Pyrobaculum aerophilum str. IM2
NP_147217 210 Rgl----rLSPLMVRETVKLVAEArgedpgrLMEAISLNSERLLG 250 Aeropyrum pernix
NP_341622 199 Pekm--srNKPCNVKIVVKQISLLkrieeieIEEKIYKNFVSLFT 241 Sulfolobus solfataricus
P45305    208 Egfe--raGISEQLLAVLQKLAELkslplhsVQKQILLNTQQFYR 250 Haemophilus influenzae
B97072    203 Ewvn-gdyGYPNVIKNVVKEISKIkniqeeeVKGVIENNFKTLIR 246 Clostridium acetobutylicum
NP_756373 199 Frn---dpLMPWDSGIAEKQLAALwgisqmeVNAQLVDNFKVLCT 240 Escherichia coli CFT073

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