Conserved Protein Domain Family
dGTP_diPhyd_N

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pfam18909: dGTP_diPhyd_N 
dATP/dGTP diphosphohydrolase, N-terminal
This entry represent the N-terminal region of SHab15497_00040, an Acinetobacter phage protein that catalyzes the hydrolysis of dGTP into dGMP, which is needed among others for the first step of biosynthesis of dZTP (2-amino-2'-deoxyadenosine-5'- triphosphate).
Statistics
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PSSM-Id: 465905
Aligned: 54 rows
Threshold Bit Score: 67.3267
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ATN94035          9 SSTGGRKGTKL-ERPDLIPPSALVELARHFGIGADKYTErdedgNvvhngayNWLRGYD--WSL---SFAALQRHALAFW 82 
EFF65354          5 AEQKYPQDEEQ-NEYRYISASWLDEIAKGLTKGAAKHPG-----E-------TWRTIP---SDE---HLSRAMRHINLYR 65 
APU03168         88 ANPKQAFGDKK-PPVHLVHGIALLAESQALHAGRRKYGE-----N-------NFIQT----PVEamtYVAGMKRHIDQWV 150
AGC36003          3 ANPKEAFGNKK-MSLSLLPLPAQLAQCEAHLDGALKYGF-----Y-------NWRVN----AVEamtYIDAAKRHLALFE 65 
Q5DN89            3 KNPKDIAATSR-VPLHLLPHIGRVWGAMACRDGAIKYAP-----Y-------NWRDKPIs-MME---YLGALERHIAALA 65  Alphaproteob...
ANH51087         70 VNPKTAQGDKK-YPLHLLPLSAQVEVNRALEDGMKKYGL-----A-------NWRET----GVPahvYVAAAKRHIEQWF 132
PEL:AKJ09_00073   6 SNPKDAVSDTK-IPLWLLSPIAKAKWAVAQFAGLLKYGA-----W-------NWRVA----GVRssvYLSAAQRHLDAYL 68 
OYQ31431         21 YDPKAEAGSKK-TPLRLIPPAAMREEAWAFELGARKYGA-----F-------NWRLEGR--RPKasvYYEAVLRHVTAWY 85 
EQB10401         25 ENPKAIYGRAK-PSLALFPAGALVPVCEVFQLGADKYGP-----F-------NWRKD----PVEamtYANAALRHIFSWI 87 
Q2NPF7            8 TDSAERKGIPLaQGVLYYFPAALAEIAKLSKAGNDKHSP-----G-------KPLHHARgkSTD---HADCIIRHLIDS- 71  Xanthomonas ...
ATN94035         83 AGE---DydlckcqepaeslPcktcgATGSK--HIIAAMWHCAVLSVFMDQYQQf---DDR 135
EFF65354         66 MGDr-tE-------------P------------HIINASMRLMMAFCTTLDDDVi---HAH 97 
APU03168        151 AGEe-fD-------------P-----VELVS--HLGAVRAGAGILLTAAACGMMi---DNR 187
AGC36003         66 HGEkfaR-------------------DTKVQ--NLGAVMACCAILIDAELHNKMi---DNR 102
Q5DN89           66 GGEw-fS-------------P-----DTDPPvpHLGHIIATAAILLDAEACGTLi---DDR 104 Alphaproteobacteria virus phiJl001
ANH51087        133 DGGqerA-------------S-----DSDVH--NLGHAMACMAIIIDAQWNGKLi---DDR 170
PEL:AKJ09_00073  69 SGEq-yD-------------P-----VDGTD--HRANIMACMSILMDAEAAGKLv---DDR 105
OYQ31431         86 DGEd-mD-------------P-----ESGRS--HLAHARAGLGILLDAIDRGRLe---DDR 122
EQB10401         88 DGAn-qD-------------H-----ESGLS--DLAHGICCLAIVLDAAANGKLi---DDR 124
Q2NPF7           72 -GTi--D-------------P-----EDGMR--HSAKVAWRALALLQEELEQAGaplaRNA 109 Xanthomonas virus OP1
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