4ZV5


Conserved Protein Domain Family
Gag_p10
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pfam02337: Gag_p10 
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Retroviral GAG p10 protein
This family consists of various retroviral GAG (core) polyproteins and encompasses the p10 region producing the p10 protein upon proteolytic cleavage of GAG by retroviral protease. The p10 or matrix protein (MA) is associated with the virus envelope glycoproteins in most mammalian retroviruses and may be involved in virus particle assembly, transport and budding. Some of the GAG polyproteins have alternate cleavage sites leading to the production of alternative and longer cleavage products (e.g. p19) the alignment of this family only covers the approximately N-terminal (GAG) 100 amino acid region of homology to p10.
Links
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Statistics
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PSSM-Id: 426727
Aligned: 8 rows
Threshold Bit Score: 107.046
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4ZV5_B         7 GQKL-FVSVLQRLLSERGLHVKESSAIEFYQFLIKVSPWFPEEGGLNLQDWKRVGREMKRYAAEHGTDSIPKQAYPIWLQ 85  Mouse mammary t...
5_pfamImport   1 NRQM-FIEILLHMLAHRGIKVSTGRLSKFLIFVQEQCPWFPEEGTINLETWTKVADRLHLFYTLHGPEKVPVDAFALCSM 79 
1_pfamImport   1 --QL-FIKAISQLLNKRGIKVKKASVQSFFTFIQEQCPWFPEGGTVNLKTWEKVGKQLKTYYTWHGPKRAPTDTFSLWNM 77 
Q9YNA8        11 KYAS-YLSFIKILLKRGGVKVSTKNLIKLFQIIEQFCPWFPEQGTLDLKDWKRIGKELK-QAGRKG-NIIPLTVWNDWAI 87  human
3_pfamImport   1 TKPHdFSTLLHHLFKVQGLSVSRQQIEACLQTVVECNPWFPDEGSFDLEIWPRDKENVE-QATRQG-KNIPIDFWP-WAL 77 
4_pfamImport   1 SHEI-FL-ALNALLRENGLKLKPSTLHRFLRNCDTIAPWYGVSGSLTIPSWDKLGRDLD-FAFEQG--NLEGGVRPIWKL 75 
XP_012906739   2 EKVV-FMTALQALMKQKGSKVSKKALQQFFCTVSELCPWFPKEGTVSLDAWQKVGQEIKNQIKIHGPTACPPSTMQVWED 80 
XP_027834983   6 SRQL-FVHMLSVMLKHRGITVSKPKLINFLSFIEEVCPWFPREGTVNLETWKKVGEQIRTHYTLHGPEKIPVETLSFWTL 84  sheep

4ZV5_B        86 LREILT 91  Mouse mammary tumor virus (STRAIN BR6)
5_pfamImport  80 IRDVLD 85 
1_pfamImport  78 IRDSLD 83 
Q9YNA8        88 IKAALE 93  human
3_pfamImport  78 IKAVIL 83 
4_pfamImport  76 VRACLE 81 
XP_012906739  81 IREVLD 86 
XP_027834983  85 IRDCLD 90  sheep
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