Conserved Protein Domain Family
DUF4430

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pfam14478: DUF4430 
Domain of unknown function (DUF4430)
Although this family has overlaps with SLBB, the majority of its sequences are unique. Several family members, eg UniProtKB:A0RGA8, that do not overlap have an LPXTG-cell wall anchor at their C-terminus, a SSF_Family 10_polysaccharide_lyase or Glycosyltransferase structure associated with them in the middle region, as shown by InterPro, as well as this domain at the N-terminus.
Statistics
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PSSM-Id: 433979
Aligned: 38 rows
Threshold Bit Score: 46.5254
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EEN53359               40 TSVFQ-MMEVVAKEFPDFTQAPLHefmhthttfhatknpklnehFVDSINGLAgNTADK---TYWRFEdGNGVPFDRGVD 115
NP_001116703          347 SSLFE-ALNLLQDKQTGFTFKTEDslw---------------gaFLSVLNDEQaRQTDR---RYWHVS-SDGTSLTQGIK 406
ripcm:ACL_0510         66 DTLQNiILNHFNDVQFEESAYGP---------------------FLVSIEGY---TMPKdyaTYISIY-INGSFSPYGIG 120
Q1G7W1                 79 TSVFT-VLKKAWKVNYTKSSYGV---------------------FITKIKGLg-NEKKK---LYWTYT-VDGKMAKVAAD 131 Lactob...
Prjna32935:ECBG_00137  63 ESLLE-VMKENFAIKEKDG-------------------------FITSIDGISqDQKAN---LFWVYT-VNDEMTDKGAQ 112
WP_005226209           72 VSLMT-IMKENFDLEENQG-------------------------MITSIDGLAqDEKAG---YYWTYT-INDEMITTGAD 121 Entero...
EQC80867               72 TSLME-IMKENFDLVEDKG-------------------------MITSIEGLAqDEAAG---YYWTYT-INDEMVNTGAK 121
WP_012658123           60 DTVME-ILKENYKVKEEKG-------------------------FIKAIDNYHqDEKKQ---VYWFFK-VNDKMASKGAD 109 Strept...
Q5M4Z4                 64 DTVLD-VLKEIYPVQENDG-------------------------FITEIDGISqDKEKG---IYWMFD-VNGKIGEKAAN 113 Strept...
Q8DV11                 59 ATVMD-VLKDNYKVKESGG-------------------------FITTIDGVTqDKKAG---RYWMFD-VNDKLASKAAD 108 Strept...
EEN53359              116 LVTVhASGEVFVFRFT 131
NP_001116703          407 DYKI-DSAQRITIKNT 421
ripcm:ACL_0510        121 DIEL-KNEMKITLKVE 135
Q1G7W1                132 KQKLtKNKSKVVFTLK 147 Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002
Prjna32935:ECBG_00137 113 ALIL-KNNDTITFDLK 127
WP_005226209          122 DTFL-GNNDKVVFTYE 136 Enterococcus
EQC80867              122 DTSL-TEKDRIVFTYE 136
WP_012658123          110 ALQV-KKGDVIYFYLD 124 Streptococcus uberis
Q5M4Z4                114 QLKV-QDGDEIKFYQE 128 Streptococcus thermophilus LMG 18311
Q8DV11                109 KIKV-KNGDKIEFYLK 123 Streptococcus mutans
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