4LMA,2EGU


Conserved Protein Domain Family
CysK

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COG0031: CysK 
Cysteine synthase [Amino acid transport and metabolism]
Cysteine synthase is part of the Pathway/BioSystem: Cysteine biosynthesis
Statistics
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PSSM-Id: 439802
Aligned: 894 rows
Threshold Bit Score: 190.26
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4LMA_A         8 M------RIAHDVTELV--G-RTPLVQLNR-IPqA-EGClgRIVMKLEGMNP-AASVKDRIGTHMINSAEKAGLINPETT 75 
WP_013336425   5 AgngsknNVFLSVSDFIrnfyPTPLVRLDR-------FG--DVWAKLEFFNPlSRSIKDRTVQFLLRKYLN--DYLHGRL 73 
WP_054049356   1 M------K-YDSITDVI--G-DTPLVRIAPeVh-GlRNI--DLYAKMEMLNP-FGSVKDRPAWNMARAGLAEAVE-RGDS 65 
WP_083859925  87 eisdpgirVYNNAIELIekdkPTPLVKLNG-IInD-EKI--KIWGKLEWYNPfSLSIKDRTAWYIIFNNLD--KINNKEK 160
WP_110138845  89 dinpeplrvfkSSLELLyrnwPTPLVRLES-LS-T-DGY--RVWAKLEWYNPySMSVKDRIGWYMIVRALETG--WRGRE 161
WP_082419648  64 didpapmrvfrDTMELLyrgwPTPLVGLRS-LS-G-DGF--RVWAKLEWYNPySMSVKDRIGWYMVKQALENG--WRGDK 136
WP_013805910   1 M------R-CDSITEVI--G-DTPLVRISPeIh-GlKNI--DLYAKLEMLNP-FGSVKDRAAWSMVRESLGDARA-EGQT 65 
ADM28580      85 dvkpsvmrvfrDTEELLyrnwPTPLVMLKS-LS-T-KDI--RVWAKLEGFNPySMSVKDRIGWYMYRKAIDRNGSRPLKL 159
BAA80586      75 disvpgemvfpSPLDFFerGkPTPLVRSR--LQlP-NGV--RVWLKLEWYNPfSLSVKDRPAVEIISRLSR--RVEKGSL 147
WP_014026652  89 dvnpepyrvfqDTLELLyrnwPTPLVRLRS-LS-G-DGY--TVWAKLEWYNPySMSIKDRTAWYMIVRALEEG--WRGDK 161
4LMA_A        76 VlVEPTSGNTGIALAMTAAAKGYRLILTMPETMSLERRAMLKAYGATLELTPGS------QGMK-GAILRAQQ-IVDSIP 147
WP_013336425  74 V-FEASSGNVAISLAALANVYGFKYRAYTTKHLPETTEVLLKVLGAEIVRVDREm-------IDeEFWRWVSK-EAVR-N 143
WP_054049356  66 I-VELSSGNTAKALAVIAAMHGLPFKSVTNRMKVPEIKDLLLLLGAQIEELPGQtecldpTDTE-DPLTRMYRmLSEEGN 143
WP_083859925 161 I-IEATSANTGISLSAISSILGKKTKILMPNSSPEYADKMLKIYGSEVVREGNS--------TN-DLIEKVKK-IAQE-E 228
WP_110138845 162 V-YETTSTNTGMALAAMGAIHGFRVKLWIPKTIQKASDVLLKALGAEVIRTDKQl-------TV-DLIEDVKT-EAKR-S 230
WP_082419648 137 V-YEATSTNTGMALAAMAAIHGFKVRLYIPRVIQKASDTLLRALGAEVIRTEKPl-------TV-DLLEDVRR-DAAR-D 205
WP_013805910  66 V-IELSSGNTAKALAVISGMHGVPFKSVTNRMKVPEIKDLLLLIGADIEELPGQaecldpTNVD-DPLTRIHQaIAQD-S 142
ADM28580     160 L-VESTSTNTGLAIAAMCAIHGSKLRAYIPSTVSKTGELLLKIFGVDVIRSQKAl-------TV-ELIDDVDK-IARE-E 228
BAA80586     148 V-ADATSSNFGVALSAVARLYGYRARVYLPGAAEEFGKLLPRLLGAQVIVDPEAp------sTV-HLLPRVMK-DSKN-E 217
WP_014026652 162 I-YEATSTNTGMALAAMGAIHGFKVKLWIPKSIQKVSDILLKAMGAEVVRRDKSl-------TV-EMISEVKE-AASR-D 230
4LMA_A       148 GAYMLQQFRNPSNPEIHRLTTAEEIWQDTE--G--Q-VDFIVAgvgtggtitgvAEVIKSRKPSFQVVAVEPFNSPVISG 222
WP_013336425 144 GAINLNQFENVDNPDGHYQVTGEEIVRQFRgvGk-V-PRVLIAgigtgghitgiARRLRDEFGNVYVVGVEPAAGSAI-- 219
WP_054049356 144 GYLHTDQYFNPLNLDAHRSGTGPEIIKDLG--G--RtPDHFIAcvgtagsssgvTAALRDHNPEVDIIGLVANKSDFIPG 219
WP_083859925 229 NAFVPDQFSNIFNVLVHLRYTAKELDYQAIy-GklR-LKGIFAsmgtgghiagiLLYFHNKYNGIKVFGVQPMENGSI-- 304
WP_110138845 231 NALHVDQFNNDANFLVHLKYTAKELELQLKhaGv-K-PKGIIGglgtsghlaalTLYFRSRMSGIRVYGVQPARGEVI-- 306
WP_082419648 206 RALHIDQFGNDANFLVHLRYTAKELELQLRtaGv-N-PRGIVGgigtsghmaaiTFYFKNRVGGTKIYMVQPAKGEVI-- 281
WP_013805910 143 TYLHTDQYFNQRNTAAHIDSTGPEIIADLD--G--QaPDYFIAcvgtagsstgvAKVLREARDDVNVIGLVAHKSDFIPG 218
ADM28580     229 NAVHLNQFHNDANFEVHLRYTAKELELQIReaGi-R-LRGIVGglgtsghmsaiSHYFKNRFSNVKIYGVVPKEGTSI-- 304
BAA80586     218 GFVHVNQFYNDANFEAHMRGTAREIFVQSRrgGl-A-LRGVAGslgtsghmsaaAFYLQSVDPSIRAVLVQPAQGDSI-- 293
WP_014026652 231 NALHIDQFNNDANFLVHLRFTAKELEVQLKhaGv-K-LKGIVGglgtsghmsaiTFYFKTRFDNIKVYGVVPAPGEVI-- 306
4LMA_A       223 GNPGPHKIQ-GIgagfIPEVLRT-DLID---EVITVSDEEAFQFGRRLAKEEGLLSGISSGANLCAAIQLAQRp------ 291
WP_013336425 220 --PGIKRLE-S-----GTRWVRE-V-VN---EVVDVGLEEAVRGVITVARNTGLLIGLSSGAVFQAFLRVRER------- 279
WP_054049356 220 IR-NIDEVN-EV------GLFDP-GTYD---TIESVTAQQAIDGMLTLNRRCGMLGGPTGGAAYFGAVRYLAMld----- 282
WP_083859925 305 --PGIKKQD-------FNKWWSIsELPD---KVFSVSFDEAVEMIVKTARNNGIIPGISGGAVLAGFKKAYEQg------ 366
WP_110138845 307 --PGIRRIEtGM------KWVHW-AKPD---NIVEVKRCEAIEALLRVARRDGILPGLSSGAVAAAFLKLLEKg------ 368
WP_082419648 282 --PGIRRVEtGM------KWIHW-VKPD---AVVEVTRREAIEALLTVARRDGILPGLSSGAVAAAFMKLRDRg------ 343
WP_013805910 219 IR-NIDEVH-EV------GLFDP-DTYD---TIESVSADEAIDGMLDLVRRCGMLAGPTGGAAYYGAQRYLQKvdgqlea 286
ADM28580     305 --QGIRRVEsGM------KWIHK-VVFD---RIVDVDPDDAAKTVIDIARREGILIGLSSGAVAYGFKTLLIEg------ 366
BAA80586     294 --PGIRRVEtGM------LWINM---LDisyTLAEVTLEEAMEAVVEVARSDGLVIGPSGGAAVKALAKKAAEg------ 356
WP_014026652 307 --PGIRRPEtGM------KWVHW-STPD---RIVDVKLEEAIEAVLSIARKDGILPGLSSGAVAAAFMKLRDSg------ 368
4LMA_A       292 --ENEGK-LIVVIQPSFGERYLST 312
WP_013336425 280 --F--GDvTYLLIFPDDIYKYVSI 299
WP_054049356 283 esLTERH-TAVFIVCDRVESYMSY 305
WP_083859925 367 -iL-EEG-DYSCIIPDNGIKYLDD 387
WP_110138845 369 -eI-EPG-DYILIFPDNGFKYVEQ 389
WP_082419648 344 -eL-EEG-DYVLVFPDNGFKYVEQ 364
WP_013805910 287 egLGQRR-SAVFIVCDRVESYMSY 309
ADM28580     367 -yI-DEG-DYILIFPDHGFKYVEQ 387
BAA80586     357 -dL-EPG-DYVVVVPDTGFKYLSL 377
WP_014026652 369 -eI-EPG-HYVLVFPDNGFKYAEQ 389
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