1ORE,1G2Q


Conserved Protein Domain Family
apt

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TIGR01090: apt 
Click on image for an interactive view with Cn3D
adenine phosphoribosyltransferase
A phylogenetic analysis suggested omitting the bi-directional best hit homologs from the spirochetes from the seed for this model and making only tentative predictions of adenine phosphoribosyltransferase function for this lineage. The trusted cutoff score is made high for this reason. Most proteins scoring between the trusted and noise cutoffs are likely to act as adenine phosphotransferase. [Purines, pyrimidines, nucleosides, and nucleotides, Salvage of nucleosides and nucleotides]
Statistics
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PSSM-Id: 273437
Aligned: 14 rows
Threshold Bit Score: 227.93
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1ORE_A         9 VEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHggr-idYIAGLDSRGFLFGPSLAQELGLGCVLIR 87  human
P07672        11 LKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIDLLVERYKNAGi----tKVVGTEARGFLFGAPVALGLGVGFVPVR 86  Escherichia coli
AAF94212       9 IKSSIKSIPDYPKKGILFRDVTSLLEDAQAYQATIQLLVEKYKDMGf----tKVVGTEARGFLFGAPLALELGVGFVPVR 84  Vibrio cholerae...
P73935         3 LKALIRDIPDFPKPGIMFRDITTLLNSPEGLRYTIDSLVEQCESQElv--pdHVVGMESRGFLFGMPLAYQMNAGFIPVR 80  Synechocystis s...
O25296         9 LLQSIREVKDYPKKGILFKDITTLLNYPKLFNKLIDTLKKRYLALNi----dFIVGIEARGFILGSALAYALGVGFVPVR 84  Helicobacter py...
CAB73184      12 LLDSIRIIPDFPKKGIIFRDITTLLNNKEALNFLLKHLKERYKDYNl----dFIAGTESRGFIFASMICAKLNLPFVPIR 87  Campylobacter j...
Q9JYB4        13 LADKIRKIENWPQKGILFHDITPVLQSAEYFRLLVDLLVYRYMDQKi----dIVAGLDARGFIIGAALAYQLNVGFVPIR 88  Neisseria menin...
AAA51769       9 VEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHggr-idYIAGLDSRGFLFGPSLAQELGLGCVLIR 87  human
P49435        10 LKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFpevkidYIVGLESRGFLFGPTLALALGVGFVPVR 89  Saccharomyces c...
WP_010874751   8 LDRAIKRFNDFPTPGILFYDITPIFLNSELFEFVLEQMAQFIQEVKa----dGIVCPEARGFIFGGALASKTKLPLVLVR 83  Mycoplasma pneu...
1ORE_A        88 KRGKLPGPTLWASYSLEYGKA-ELEIQKDALE--PGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKG 164 human
P07672        87 KPGKLPRETISETYDLEYGTD-QLEIHVDAIK--PGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFDLGG 163 Escherichia coli
AAF94212      85 KPGKLPRQTVAQSYELEYGTD-TLEIHVDAIK--PGDKVLVVDDLLATGGTIEATTKLIRQLGGEVEHAAFVINLPEIGG 161 Vibrio cholerae...
P73935        81 KPGKLPAPVHRVEYDLEYGKD-SLEIHQDAVA--PHHRVLIVDDLIATGGTAKATAELLTKLGCEVLGFAFIIELAALNG 157 Synechocystis s...
O25296        85 KKGKLPAHTLSQSYSLEYGSD-SIEIHSDAFRgiKGVRVVLIDDLLATGGTALASLELIKALQAECIEACFLIGLKELPG 163 Helicobacter py...
CAB73184      88 KPGKLPFETFSCEYDLEYGSD-KVELHKDAFKniQNARVLLVDDLIATGGTAIASYELIQKAGAKCVEACFLINLKDLNG 166 Campylobacter j...
Q9JYB4        89 KKGKLPFETVSQSYALEYGEA-AVEIHTDAVK--LGSRVLLVDDLIATGGTMLAGLELIRKLGGEIVEAAAILEFTDLQG 165 Neisseria menin...
AAA51769      88 KRGKLPGPTLWASYSLEYGKA-ELEIQKDALE--PGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKG 164 human
P49435        90 KAGKLPGECFKATYEKEYGSD-LFEIQKNAIP--AGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKG 166 Saccharomyces c...
WP_010874751  84 KPHKLSGELARETYDLEYRQNsILEMRVDALe--NCKRCVIVDDLLATAGTVAAIDKLIARLGSQTVGYCFLIELQKLHG 161 Mycoplasma pneu...
1ORE_A       165 REKLAP--VPFFSLLQY 179 human
P07672       164 EQRLEKqgITSYSLVPF 180 Escherichia coli
AAF94212     162 DKRLEGlgLQVYSICEF 178 Vibrio cholerae O1 biovar El Tor str. N16961
P73935       158 RQCLPD--LPIISLVEY 172 Synechocystis sp. PCC 6803 substr. Kazusa
O25296       164 -IQLLEerVKTFCLLEC 179 Helicobacter pylori 26695
CAB73184     167 -ANKLEklTSVYSVLEI 182 Campylobacter jejuni subsp. jejuni NCTC 11168
Q9JYB4       166 GKNIRAsgAPLFTLLQN 182 Neisseria meningitidis MC58
AAA51769     165 REKLAP--VPFFSLLQY 179 human
P49435       167 RSKLNA---PVFTLLNA 180 Saccharomyces cerevisiae S288c
WP_010874751 162 KAKLQPn-VATKILLHY 177 Mycoplasma pneumoniae
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