7C96,1T1H


Conserved Protein Domain Family
RING-Ubox_PUB

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cd16664: RING-Ubox_PUB 
Click on image for an interactive view with Cn3D
U-box domain, a modified RING finger, found in Arabidopsis plant U-box proteins (AtPUB) and similar proteins
The plant PUB proteins, also known as U-box domain-containing proteins, are much more numerous in Arabidopsis which has 62 in comparison with the typical 6 in most animals. The majority of AtPUBs in this subfamily are known as ARM domain-containing PUB proteins, containing a C-terminally-located, tandem ARM (armadillo) repeat protein-interaction region in addition to the U-box domain. They have been implicated in the regulation of cell death and defense. They also play important roles in other plant-specific pathways, such as controlling both self-incompatibility and pseudo-self-incompatibility, as well as acting in abiotic stress. A subgroup of ARM domain-containing PUB proteins harbors a plant-specific U-box N-terminal domain.
Statistics
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PSSM-Id: 438326
Aligned: 62 rows
Threshold Bit Score: 72.5956
Created: 14-Apr-2015
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
 
E2 binding site
Conserved site includes 9 residues -Click on image for an interactive view with Cn3D
Feature 1:E2 binding site [polypeptide binding site]
Evidence:
  • Structure:7C96; Glycine soja GmPUB13 in complex with inhibitor Avr1D in E2 binding site, contacts at 4A
    View structure with Cn3D

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1          #  # ####                   #   #        #           
7C96_B          8 PDDFRCPISLELXKDPVIVs-TGQTYERTCIEKWLQAGhgTCPKTQQTLTSTVL 60   Glycine soja
XP_002682206   79 HENHICPISHTLMVDPVVLadSGITYERSSIEKWLEKSr-TCPISKKRLAGNVN 131  Naegleria gruberi strain NEG-M
EKX42263       31 PEEFCCGITREVMVDPVLLvhSGMSYERVAIEKWLKISk-KCPLSGKFSSIPRV 83   Guillardia theta CCMP2712
CDW79897       82 LNSFLCPITQQIMKEPVMTk-YGHCFEKSAILDWIERQg-KCPLTQQPLTKQDL 133  Stylonychia lemnae
XP_004365077   64 LEAFNCPITQEVMSDPVSTp-YGHCFERDAIERWLQTHk-TCPMTKKPLTQAQL 115  Capsaspora owczarzaki ATCC 30864
GAQ87719      101 PDAFVCPITKALMSDPVMLveTGKTFERAAIEEWLATHd-TCPIERSKKLQKKD 153  Klebsormidium nitens
GAQ84684       41 PDRFLCPLTKDIMLDPVIVt-SGRVYERSAIERWLKNHd-TCPVNRVPIDPKIL 92   Klebsormidium nitens
GAQ82728      845 VQPEICSITRQPMKDPVIIe-SGHTFERAAIERWFKKHn-TCPITRVKLRRRTM 896  Klebsormidium nitens
OMJ71947       99 NDLLLCPISQELMTDPVMTp-YGHCFQRKNIEAWLSNHk-TCPLTNNPLEISQL 150  Stentor coeruleus
GAX16332       22 PDEFICPITMEVMEFPLMTr-TGLNFDRDAILQWIKTNg-SCPLTRKPMRPSDL 73   Fistulifera solaris

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