Conserved Protein Domain Family
ATPgraspMvdC
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TIGR04185: ATPgraspMvdC 
ATP-grasp ribosomal peptide maturase, MvdC family
The pair of ATP-grasp proteins MvdD and MvdC (microviridin D and C), as well as an acetyltransferase, produce microviridin K, an example of a RiPP (ribosomally synthesized and posttranslationally modified peptide). Microviridins are peptidase inhibitors. This family includes MvdC and corresponding members of similar cassettes.
Links
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Statistics
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PSSM-Id: 275038
Aligned: 8 rows
Threshold Bit Score: 500.781
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
ZP_01629958    8 VLLITHRGDFFTIDRVAEALSKKGVQPFRLDTDRFPLEVQLTAHFDNNKTYHTIDYGGYCISTE-QVQAVWLRRIWEPKL 86  Nodularia spumi...
ZP_01694123    3 ILLLTHSGDFFTIDRVQQALEAIGTHPIRINTDLYPEEIKVNFHLEAGTPKVFIETPQGTIDTD-EVEGVWMRRIWKPRL 81  Microscilla mar...
ZP_03156482    8 VLLITHSGDYFTIDRVAEALASKGVQPFRFNTDQFPVAVQLTAQFDNSKSHYRLEIGTESITTE-QVKAVWMRRIWEPDL 86  Cyanothece sp. ...
EFK33431       2 ILCITHSQDFYNIDIFFEYLSSKNIPYFRLNSDRLNHLQKISICENS----FELTDESGNTIHSdDIKGVWHRKAWRISA 77  Chryseobacteriu...
WP_010999572   8 VLLITHSGDYFTIDRVAAALSRRNVQSFRLDTDKFPMTVKIQAYFHQSNSHHQIEYGDITLNTE-QVQAVWMRRLWQPHL 86  Nostoc sp. PCC ...
WP_012265554   8 VLLLTHSGDFFTIDRVAEAIEKKGATPFRLDTDKFPLEVQLAAQFNGKKSFYQLTYNHQSIDSE-QVQSVWTRRIWQPEI 86  Microcystis aer...
WP_012625820   8 VLLLTHTGDYFTVDRVAAALSNRGVIPFRLDTDQFPLNIALAAYLQLQGLKHCLTYRNQSIAPE-AIQAVWMRKLWQPQL 86  Cyanothece sp. ...
WP_012239783  15 VLLVSHSQDDFGIGRVAEALRRRGARPVRLDVDRFPRDIKLSTALGPGGVRRRLEDAGAEIGGD-EISAVWLRRLWAPNL 93  Sorangium cellu...

ZP_01629958   87 SADLAPKFREACIRESQATLNGFWDSLRKAHWVDKLECINAAS-DKLRQLRVATQAGFVIPQTLVTNKAEAARKFFQQVN 165 Nodularia spumi...
ZP_01694123   82 DKEIQGDFRNICLGESQTVLRNSLLLLDHAVWLDPLEHISRAS-NKLYQLKLAVKHGLQVPATLITNEAAQALSFYENKQ 160 Microscilla mar...
ZP_03156482   87 -KELDPQYQKACATESLATLEGFWDSLREAHWVDHLEKINAAN-NKQLQLRLASEVGLNIPRTLITNKAEAAREFFQQLE 164 Cyanothece sp. ...
EFK33431      78 PEELDQDYERIFLNEYGSLRYNLMTALEHVPWINPYENEKKVDgNKIFQLKTAQRNNLAIPKTIFSNDEEKITTFFHQYC 157 Chryseobacteriu...
WP_010999572  87 SPELAPQYRDACTKESLAVWDGFWDSLRHAHWVDDLQKINAAE-NKLYQLRVAAEVGLVIPPTLVTNNPKEAREFFEQVN 165 Nostoc sp. PCC ...
WP_012265554  87 TADLDPQFREACVRESQTTLASFWDSLRSARWLDNLAQIERAK-NKLLQLRLASEVGLIIPPTLVTNNPDAAREFFSQVQ 165 Microcystis aer...
WP_012625820  87 SPDLDPRFRDGCARESRAALQGFLDALADVRWIDPLERITAAE-NKLRQLRIARQAGLMIPRTLVTNSPEAAREFFQDLG 165 Cyanothece sp. ...
WP_012239783  94 GEGIPEEYRGACVRESMAALTGWLRGLPARRWINEPAAEERAQ-DKLRQLAAAASVGLRVPETVVTNDPAEVRGLFARLG 172 Sorangium cellu...

ZP_01629958  166 g-KMVSKLLTPLSRTMESTSFFLYTSVIKQSDLENAESLRYCPMVFQEQIPKQWELRVVYVNGKVFVGALDASVYDTSKV 244 Nodularia spumi...
ZP_01694123  161 --DIITKMHDQTDYGMGRSAMQMNTYKVTPEHVEEFESLQYCPMTFQKEIKKACELRVVYVGGEFFTGAIDTSQSAQGGT 238 Microscilla mar...
ZP_03156482  165 g-KIVSKLLTHISRSMEYSSFYLYTNKVTEEDLLDAESLRYCPMVFQELIPKEQELRVAYVNGNVFAGALNSSVYNDKSV 243 Cyanothece sp. ...
EFK33431     158 qgKAIAKLHGVTSKTMS-GENMISTTVIEEESLEHLSDIAYCPMIFQPYIDKEYELRIVYVDGDFFTGKINNSE----NA 232 Chryseobacteriu...
WP_010999572 166 g-KMITKLLKPLSYSMEGSSFFMYTSTVKEEDLLDAETLRYCPMVFQAQIPKQQELRAVYVNGNLFVGALDASSYEASTQ 244 Nostoc sp. PCC ...
WP_012265554 166 g-RMVSKLLTAIARSMESPEFFLYTSRVKAEDLEEAESLRYCPMVFQAEIPKQLELRVVVVNGQTFVGALESSQYNNSAV 244 Microcystis aer...
WP_012625820 166 g-NMVAKLLTPLSYGMAGSSFFVYTSAVKEADLVEAESLRYSPMVFQECIPKQRELRAIFVGGSLFVGALDPSTYATETI 244 Cyanothece sp. ...
WP_012239783 173 g-NVVAKMLTPFSTSLAGGAPFVFTHAVAEADLDALSGLRQSPMVFQERIPKARELRVACVDGRCFPGALDATRYESIAV 251 Sorangium cellu...

ZP_01629958  245 DWRKPGVDVG--VWQNYELPEQVLRRLQIFMDKLGLLFGALDFIVTPSEDYVFLEINPIGEWGMLEKDLDLPIANAIADT 322 Nodularia spumi...
ZP_01694123  239 DWRRSEINEA--EWTHFSLPADVRAKLVSFMDELHLSFGALDLIHTPNDEYVFLEVNPLGEWGMLERDLDLPISKAIAHT 316 Microscilla mar...
ZP_03156482  244 DWRRPGVNPG--SWQHHQLPEELVSRLRNFMGRLGLLFGSFDFILTPSGEYVFLEVNPIGEWGMLEKDLDLPISKAIADT 321 Cyanothece sp. ...
EFK33431     233 DWR---VAREgyFWSAYELPETIKASLTSMMKEMGLYLGAIDMIKGRDGAYYFLEVNPQGEWGMLQKELGFPIAERIADN 309 Chryseobacteriu...
WP_010999572 245 DWRRANQESC--TWQPYELPKEIIQHLDQFMARLGLTFGAFDFIVTPLEEYVFLEINPTGEWGMLERDLNYPISEAIADS 322 Nostoc sp. PCC ...
WP_012265554 245 DWRRPGIDPG--AWQHHTLPDSLLQQLQIFMANLGLNFGAFDFILTPGGEYVFLEVNPGGEWGMLERDLDLPISNAIADF 322 Microcystis aer...
WP_012625820 245 DWRQTRPERV--CWEKAQLPDDVAHGLTILMAELNLTFGAIDLIQTPTGEYIFLEVNPTGEWGMLERDLSYPIAATIADA 322 Cyanothece sp. ...
WP_012239783 252 DWRHPDVSEVgiGWEPDALPRDVEARLGALLRALGLVFGAVDLIRTPDGEHVFLEVNPAGEWGMLERDLGLPIadalaea 331 Sorangium cellu...

ZP_01629958  323 LLL 325 Nodularia spumigena CCY9414
ZP_01694123  317 LYK 319 Microscilla marina ATCC 23134
ZP_03156482  322 LIS 324 Cyanothece sp. PCC 7822
EFK33431     310 LIK 312 Chryseobacterium gleum ATCC 35910
WP_010999572 323 LIQ 325 Nostoc sp. PCC 7120
WP_012265554 323 LVF 325 Microcystis aeruginosa
WP_012625820 323 LLA 325 Cyanothece sp. PCC 7425
WP_012239783 332 lla 334 Sorangium cellulosum
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