Conserved Protein Domain Family
AspB

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COG0436: AspB 
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]
Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Statistics
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PSSM-Id: 440205
Aligned: 767 rows
Threshold Bit Score: 164.533
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_013682512   1 M----------Lg-NpdKKF---------SNffngVKP---SGLRLAQTVfe---krAQkelkeGKrpiE-AVNVAIGSV 53 
AFH42875       1 Mr--------kI--S--SRS---------QK----ISP---SLHRLISNKmde--lkRK-----GV---E-TYNFTQGQP 41 
WP_108673100   1 Mi--------qL--E--SEIlfyydttmmKS----FSD---TGIIHVMNEaaqy------gyynGNi--E-WANLGQGSP 52 
NP_603502      1 Ms--------mV--E--EKF---------KK----LGVe-nAPGQELLQKgvk--ldLK-----GEkilGeKIDFSHGDV 47 
WP_005856221   1 Mkn------tpVdyQtaRRIi--------DGf--gLPDfgkATIREVVAIstq-leqET-----GT---E-FIHMEMGVP 54 
WP_020962130   1 Mp--------rL--A--SKP---------QT----ITA---SPIRRIATLld---eaRR-----KS---D-IISFGGGAP 40 
WP_011749671   1 Mn---------I--Q--NKF---------AR----LATd-nAPGQEVRQNaagiqalLR-----GDvlpGrPVDFSHGDV 48 
WP_011978518   1 MtlsftdtatpIdfDkvTHTl--------KEa--gIPSlarASIRELVALvnr-iesAT-----GE---Q-FIRMEMGVP 60 
WP_002724247   1 Ms---------I--E--AKF---------KK----LGTd-nAPGQEVRQSaaglealMR-----GApieGrPVDFSHGDV 48 
WP_013390775   2 Na---------I--E--EKF---------LK----LGId-nAPGQEVREShggerllHE-----GAslpGvAVDFSHGDV 49 
WP_013682512  54 S---LKTHPKLLERF-LN-PTNEelinG-IWRYGETPGTQKANEVFIKIIRAFlpdG------VNPkLYSIIQDGGSGAM 121
AFH42875      42 G---FPPDENIIKAT-FEhALKNs--fD-HYRYLPTQGLPELRTDISDELKESg--Gi----sIDP-SNIVVTSGGIEAL 107
WP_108673100  53 E---TGVLSEMKRFAfLE---SDd---S-TSEYAAVAGRSDTRSSIAKLYNQRy--RstmssqYDC-DNIALVSGGRLAV 119
NP_603502     48 Da--HKPLPNSLELF-IE-GFNKg---G-IQAYTEYKGNKEIREYIAGKLSEYi--Km----nIPA-DNLIITPGTQGAL 112
WP_005856221  55 G---LKAAQVGVDAE-IE-ALRN----GiASIYPNINGTPEVKKQASRFIKAFi--Ni----dIDP-ECCVPVTGSMQGT 118
WP_020962130  41 S---LPPPQEVIDHL-IN-YIKSyp-qK-AVGYGATRGMIELRELIAEDLKKYw--Nv----sYDPkEEIMIVNGGTEGI 107
WP_011749671  49 Da--HEPTPGAFEVF-AQ-GVARg---G-RQAYTEYRGDLEIRETVAARLAGFt--Ga----pIDArDGMIVTPGTQGAL 114
WP_011978518  61 G---LPAPSVGIEAE-IA-ALHQ----GvASKYPMLEGIPQLKQEISRFCSLFm--Ni----nVSP-TGCFPTVGSAQGA 124
WP_002724247  49 Da--HEPTPGAFDLF-SA-GVQSg---G-VQAYTEYRGDLGIRDLLAPRLAAFt--Ga----pVDArDGLIITPGTQGAL 114
WP_013390775  50 NagaFEPTPGALDAF-VQ-GVHRg---G-SQAYTEYRGQSAIREKLALDLAAFs--Gh----pVSGaEELIITPGTQSAL 117
WP_013682512 122 RTAILGL--CgDA-GkDdrPLLVMNPTYTNYKAVADELGR-RIVAVERAl---------DRsGnFnHVAVEKIEEAVK-K 187
AFH42875     108 HLTFYAT--T-DP-G-D--RAFFLDPTYSVYWDIANMYNL-KVDSCEQN----------GE-D-F-QPDPECLKEKIN-R 165
WP_108673100 120 TRIIACL----QP---T--NIGYFVPDYTPYQSIIGLFNGhNAIPIVLNk---------ED-G-Y-SISIEKLRATVKlH 178
NP_603502    113 FLATGSL--I-TR-G-T--KVSIVEPDYFANRKLVEFFEG-EIVPIELDyfn-----vnEK-K-A-GLNLKQLEEAFK-S 175
WP_005856221 119 YASFLTAgqC-TP-GkD--TILFIDPGFPVQKQQIAVMGY-KYESFDVYe---------YR-Ge--RLRE-ALEAHLS-K 179
WP_020962130 108 YLALGAI--L-EK-D-E--EVIVLDPTYLGYHEPIKLFGG-RVRTVPVSv---------EN-G-Y-QPKIEDVKKVIS-P 166
WP_011749671 115 FLAVAAT--V-AR-G-D--KVAIVQPDYFANRKLVEFFEG-EMIPVRLDyetvdyetagED-R-A-GLDLDQLEAAFR-G 182
WP_011978518 125 LAAFLVGnrT-KEqG----ATLFIDPGFPNQKRQLDMIGQ-SWGSFDVYn---------HR-Ga--ALKP-ELEKHLS-S 184
WP_002724247 115 FLAVAAT--V-AR-G-D--KVAIVQPDYFANRKLVEFFEG-EMVPVQLDyvs-----adET-R-A-GLDLTGLEEAFK-A 177
WP_013390775 118 FLAVAST--V-TA-G-E--KVAIVQPDYFANRKLVEFMGA-EMIPVQLDyl------nnTA-H-A-GLDLQQLESAFK-A 179
WP_013682512 188 yKPGALLIIPYDNPSGQLMRQKTINEYVRICLENDMFIISDEAYRGLYY--T-DD--E----PP-SVWRVtnkdvPGV-E 256
AFH42875     166 -NTSLILVTSPDNPTSRILSEDIFKLIADLAVDNDVWLLYDEAYRNIIY--E-G---K----HV-WIQKY-----SRT-L 227
WP_108673100 179 -KISVVVMSNPSNPIGKLTSEQQMIELIKLAEEEQFLLLIDEVYSHYIY--D-RP--EvdipYTfSAARYv----REIdS 248
NP_603502    176 -GVELFLFSNPNNPTGVIYSDEEITEIARLVNKYNVTVIADELYSRQIF--D-NR--E----FY-HLITK-----NIN-Q 238
WP_005856221 180 gNIAAMIYSNPNNPAWFCLTDEELKIIGEMANKYDVIVIEDLAYFAMDFrkDlGCpfEp--pYQaSVA--------RY-T 248
WP_020962130 167 -LTKAFILLSPDNPTGRVVTEEFVRDLVDLAVEHDFWIIFDAVYKHISY----GR--P----TP-WVDSF-----KGA-R 228
WP_011749671 183 -GARVFLFSNPNNPAGVVYSPAEIARIAALAGQYGATVIVDQLYSRLRY--S-GV--T----YT-HLRAQ-----DVD-P 245
WP_011978518 185 gKYATLLYSNPNNPAWICFNEEELQIIADVARRYDVIVIEDLAYFGMDYreDyATpgQa--pYQpSVA--------HY-T 253
WP_002724247 178 -GARVFLFSNPNNPAGVVYSAEEIGQIAALAARYGATVIADQLYSRLRY--A-GA--S----YT-HLRAEa----AVD-A 241
WP_013390775 180 -GAKVFLFSNPNNPTGAVYSRNEIGQIAALAERFGATVIVDQLYSRLLY--A-GQ--P----YV-HLRGV-----PQA-D 242
WP_013682512 257 EAgiRISIESLSKTFNSCGLRMGALVT-DNEAFR-DRASAANTT-----------------YLCPSIIDQHIVEGLYDES 317
AFH42875     228 EK--LVGLDTFSKDLAIPGLRLGYLYAeNKDLIK-EVLKLKGIV-----------------SISSDSSAQWMAHIALSSG 287
WP_108673100 249 SN--VIIVDGLTKNWRYPGFRLAWIIA-SKAIIK-IATNCGAFM-----------------DGGASNVVQKNALHLLDE- 306
NP_603502    239 DK--LITIIGPSKTESLSGFRLGIAYG-SPTIIK-RMEKLQAIT-----------------TLRTAGYNQAVLKSWFSEP 297
WP_005856221 249 DN--YIMQISGSKAFSYAGQRIGVTAI-SNKLYHrSYPGLTQRYgggtfgtvyihrvlyalSSGTSHSAQFALAAMFKAA 325
WP_020962130 229 ER--TITINSFSKEASIPGFRLGYITG-PPEAIE-VMEKLKQYV-----------------SLAPDTPGQIAMIKFLESG 287
WP_011749671 246 QN--IITIMGPSKTESLSGYRLGVAFG-SPAIIA-RMEKLQAIV-----------------SLRAAGYCQAVLRTWFAEP 304
WP_011978518 254 DQ--YILLISSSKVFSYAGQRVASLVI-SDALYQqEFTTLKTNFgqtqfgkaitfgamgglSAGVTHSAQYGLAAMLKAA 330
WP_002724247 242 EN--VVTIMGPSKTESLSGYRLGVAFG-SKAIIA-RMEKLQAIV-----------------SLRAAGYSQAVLRGWFDEA 300
WP_013390775 243 DN--VVTIMGPSKTESLSGYRLGVAFG-NARIIQ-RMEKLQAIV-----------------SLRAPGYCQAVLQTWFSEP 301
WP_013682512 318 y-E--DirgWVAS-LRDYYKDLLEHMYDEFKKRmpKAIV-SKPE-------ASIYMVLDLREMvdd-sfEAEDFVMYCar 384
AFH42875     288 mlKi-----YLSK-VIPKYRSRRDAAYETIREFlpEAKV-TKPI-------AGMYLFPDLSPYlskkgmDDTSFAIKL-- 351
WP_108673100 307 --KivSl--EVRE-MQKHFRAKRDYVIGELVEH--GITVdVIPQ-------GAFYVWANLSNLpes-lqDGVRFAKSC-- 369
NP_603502    298 --D--G---FMKD-RIEKHQAIRDNLIEKFKTId-GIKI-RKTE-------AGSYIFPTLPELe----vNLGDFVKIL-- 354
WP_005856221 326 --A--DgtfDFVS-QVKEYGRRAEKLKKIFTDH--GFTI-VYDHdldqpiaDGFYFTIGYPGm------TGGQLMEEL-- 389
WP_020962130 288 ikD--R---YLNEiVLPTYKRRRDFMYKCIQEYlpEAKT-SLPE-------GAFYFFVNLEEYlkamerDDEEFANRL-- 352
WP_011749671 305 --E--G---WMDE-RIRRHQAIRDDLLAVLRGId-DGFA-RAPQ-------AGSYLFPRLPALa----vSHADFVRIL-- 361
WP_011978518 331 --N--DgelPFLN-LTKVYEKRAAIMKKLFIDH--GFEI-VYAEdngkalsDGFYFTFSYPGm------DSDSLLEAL-- 394
WP_002724247 301 --P--G---WMED-RIARHQAIRDELLRVLRGCe-GVFA-RTPQ-------AGSYLFPRLPKLa----vAPAEFVKIL-- 357
WP_013390775 302 --A--G---WLAD-RIGRHQQIRDDLLSLFRGIe-GVAV-RTPQ-------AGSYLFPQLPKLh----mTLQTFIRTL-- 358
WP_013682512 385 egeVEiDgkrYTLLVSPMWGFynvieGRNpGH---------TQVRIACV-E-P-EDKMRIVPELFSRL---FEE 443
AFH42875     352 ---SE-E---KGVGVLPGSIF-----GKA-GK---------GHVRITFV-TmQ-EERIKKGIKLMSEF---LTA 398
WP_108673100 370 ---LR-E----CVIVVPGMYF-----DDQ-SDqilanvrfrNYVRISFG-Q-G-MDTLKRGMEGIKRV---IRH 423
NP_603502    355 ---RI-Y---ANVIVTPGTEF-----GKS-FI---------NSIRLNFS-Q-D-EKKAAEGVDRILEM---IRR 400
WP_005856221 390 ---Vy-----YGVSAISLSTt-----GSNq-Q----------GLRACTSfI-K-DHQYDLLDERLRLFe---EN 434
WP_020962130 353 ---LY-R---KSVVVIPGKYF-----GEM-GK---------GHVRMTFV-S-EpEERIEEGLKRMNAY---VYS 399
WP_011749671 362 ---RL-Q---AGTVVTPGTEF-----SPH-HG---------DCVRLNFS-Q-D-HRAAVAAVERMAAL---VER 407
WP_011978518 395 ---Ly-----HGISAISLLNt-----GSErVE----------GARACVS-QvK-DEQLADLETRLNAFqarLNP 443
WP_002724247 358 ---RL-Q---AGVVVTPGTEF-----SPH-TA---------DSVRLNFS-Q-D-HEAAVAAARRIVAL---VER 403
WP_013390775 359 ---RS-R---ANVTVTPGTEF-----SPH-AG---------DSIRLNFS-Q-N-HEAAVDAVKRIATV---LEE 404
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