1WEL


Conserved Protein Domain Family
RRM3_RBM12
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cd12512: RRM3_RBM12 
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RNA recognition motif 3 (RRM3) found in RNA-binding protein 12 (RBM12) and similar proteins
This subfamily corresponds to the RRM3 of RBM12. RBM12, also termed SH3/WW domain anchor protein in the nucleus (SWAN), is ubiquitously expressed. It contains five distinct RNA binding motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), two proline-rich regions, and several putative transmembrane domains. The biological role of RBM12 remains unclear.
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Statistics
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PSSM-Id: 409934
Aligned: 6 rows
Threshold Bit Score: 205.852
Created: 21-Sep-2011
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1WEL_A         17 RSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAALCRHKQYMGNRFI 96   human
NP_001079993  421 RSRSPHEHGFCVYLKGLPYEAENKHVIDFFKKLNIVEDSIYIAYGSNGKATGEGFLEFRNEEDYKSALCRHKQYMGNRFV 500  African clawe...
NP_001003856  415 RSRSPHKLDYCVYLKGLPYEAENKQIFEFFKNLDIVEDSIYIAYGPNGRATGEGFVEFRNEMDYKAALGCHMQYMGSRFI 494  zebrafish
NP_996869     422 RSRSPHEQGFCVYLKGLPFESENKHVIDFFKKLDIVEDSIYIAYGPNGKAIGEGFVEFRNEADYKAALCHHKQYIGNRFI 501  chicken
XP_005986784  421 RSRSPLKVDFCVYLKGLPYEAENKHVIEFFKKLDIVEDSIYIAYGPNGRATGEGFVEFKTEIDYKAALCRHKHYLGNRFI 500  coelacanth
XP_007910685  439 RSRSPHDKEFCVYLKGLPYEAENKHIMEFFSKLELIEDSIYIAYGPNGRATGEGFVEFKTVIDYQAALCRHKQYMGNRFI 518  elephant shark

1WEL_A         97 QVHPItKKGMLEKIDMIRKRL 117  human
NP_001079993  501 QVHPItKKAMLEKIDMIHKKM 521  African clawed frog
NP_001003856  495 QVHPItKKNMYEKIDAIRKRM 515  zebrafish
NP_996869     502 QVHPItKKAMLEKIDLIRKRL 522  chicken
XP_005986784  501 QVHPIsKNGMLEKIDLIRKRL 521  coelacanth
XP_007910685  519 QVHPItKKAMLEKLEMIHKRT 539  elephant shark
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