2DNN


Conserved Protein Domain Family
RRM2_RBM12
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cd12747: RRM2_RBM12 
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RNA recognition motif 2 (RRM2) found in RNA-binding protein 12 (RBM12) and similar proteins
This subgroup corresponds to the RRM2 of RBM12, also termed SH3/WW domain anchor protein in the nucleus (SWAN), which is ubiquitously expressed. It contains five distinct RNA binding motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), two proline-rich regions, and several putative transmembrane domains. The biological role of RBM12 remains unclear.
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Statistics
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PSSM-Id: 410141
Aligned: 6 rows
Threshold Bit Score: 147.631
Created: 25-Jan-2012
Updated: 25-Oct-2021
Structure
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Program:
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2DNN_A         16 DLYVSVHGMPFsAMENDVRDFFHGLrvDAVHLLKDHvGRNNGNGLVKFLSPQDTFEALKRNRm-LMIQRYVEVSPA 90   human
NP_001079993  303 DPYVCLHGLPLpVSEADIKELFHGLriDGIVILTDPmGRHNGSALVKLITPHDTFEALKRNRm-LMGQRFIEVSPA 377  African clawed frog
NP_001003856  301 DFYVHLHGLPFsVLEHEIRDFFHGLgiESIRLLKDNlGRNSGRALVKFYSPHESFEALKRNAg-MIGQRYIEVSPA 375  zebrafish
AAP69823      303 DLYVSIHGMPFsATESDVKEFFLGLrvDAIHMLKDHvGRNNGNGLVKFFSPQDTFEALKRNRm-LMIQRYVEVSPA 377  chicken
XP_005986784  305 DLYVRLHGMPFsSTETDVREFFYGLqvEAVQMMSDHlGRSNGNAFVKFFTPQDTYEALKRHRm-MMGQRYIEVSSA 379  coelacanth
XP_007910685  314 DLYIHLYGMPYaATEADVRDFFHGLriDAVHMMKDHlGRSNRDAIVKFYGPSDTFEALKRHGkmMMGQRFANVFPA 389  elephant shark
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