1YVL,1BGF


Conserved Protein Domain Family
STAT_int
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smart00964: STAT_int 
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STAT protein, protein interaction domain
STAT proteins (Signal Transducers and Activators of Transcription) are a family of transcription factors that are specifically activated to regulate gene transcription when cells encounter cytokines and growth factors. STAT proteins also include an SH2 domain.
Links
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Statistics
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PSSM-Id: 214942
Aligned: 22 rows
Threshold Bit Score: 113.539
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1YVL_A         2 SQWYELQQLDSKF---LEQ-V-HQLYDDSFPM-EIRQYLAQWLEKQ-DWEHAAN-----D--V--------SFATIRFHD 59  human
XP_859870      2 AGWIQAQQLQGDA---LRQ-M-QVLYGQHFPI-EVRHYLAQWIESQ-PWDAIDL-----D--Npq----drAQATQLLEG 63  dog
ACU12487       2 AVWIQAQQLQGDA---LHQ-M-QSLYGQHFPI-EVRHYLSQWIEGQ-LWDAVDLen-pqE--E--------FKAKRLLDS 63  Chinese perch
CAG11249     100 AQWQKLLSLDSEL---QDG-V-TQLYEGKFPR-ELRHWLCSQIESH-NWGLAAS-----D--E--------NEANACFHS 157 spotted green p...
NP_001124062   2 AQWAQMTQHIQFL---TTE-VlNELYPVTFPL-DIRHYLASWIEGQ-QWDSFDV-----D--N--------REQESQAQL 60  zebrafish
XP_311053      2 SLWARVNQLPQPI---LEQ-I-RFIYGSNFPI-EVRHYLADWIEERlLNAPVYT-----NdqE--------AVYEQDAAN 62  Anopheles gambi...
NP_001071828   2 SLWAKVRELEGDS---LRQ-I-QNLYGPNFPI-EFRHYFADIIERQ-QWDQLDPdnipqD--E--------PHAKYILGL 64  Ciona intestinalis
AAP36044       2 SLWG----LVSKM---PPEkV-QRLYVD-FPQ-HLRHLLGDWLESQ-PWEFLVG-----S--D--------AFCCNLASA 55  human
XP_003342234   2 SLW----SLVSKM---PPEkF-QGLFVQ-FPQ-HLRHLLGDWLENQ-PWEFLGG-----S--D--------AFSCRIAST 55  gray short-tail...
BAE06716      75 GQWNRVERLSSIRnkvVES-M-IYKFCQETPMlKFRIMFADVIESK-CWHLIDS-----N--DcqpgginmRRASTIVSC 144 Ciona intestinalis

1YVL_A        60 LLSQLDDQYSRFSLEn-------------NFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKILENAQR 121 human
XP_859870     64 LVQELQKKAEHQVGEd-------------GFLLKIKLGHYASQLQNTYDGCPMELVRCIRHILYNEQRLVREANN 125 dog
ACU12487      64 LIQELQNKAEHQVGEd-------------GFLLKIKLGHYASQLKSTYDRCPLELVRCIKHILYTEQRLVREATN 125 Chinese perch
CAG11249     158 LLDYLEEQWKRSVQEh-------------SILQGPDFAGMRAYLLKNFQDNPKYLATILFECLEMEKRILDAAAE 219 spotted green puffer...
NP_001124062  61 LSDQMVMLLHQVAKQn------------pNVVEKVKLQHM-SKNWSVLYPQPLQLVRTVREILRKERLILSQTNM 122 zebrafish
XP_311053     63 FLNQLIMELERTAINlp----------esNFTIKIRLNESARNFRQLFSHNPAQLYQHLMNCLHRERQCVAYPDE 127 Anopheles gambiae st...
NP_001071828  65 FLEEIQKQCDS-LTEg------------kDFLQRLHFSEIASHFKNVYGPAPLELVRTVKKILSIETRLVQHASS 126 Ciona intestinalis
AAP36044      56 LLSDTVQHLQASVGEq--------------gEGSTILQHI-STLESIYQRDPLKLVATFRQILQGEKKAVMEQFR 115 human
XP_003342234  56 LLSETVQQLKSAAGEq--------------gEGRTTLQHI-SSLENLCQRDPLKLVSTFRQILQGEKVAVLEQFH 115 gray short-tailed op...
BAE06716     145 LQEAVAGRLNDSYMQirvpidggrggnllSVKVKSELLNWEQELRGRYTQRPMELVQVMQKMLKREQYILEMAEK 219 Ciona intestinalis
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