3TAN


Conserved Protein Domain Family
PolA

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COG0749: PolA 
DNA polymerase I, 3'-5' exonuclease and polymerase domains [Replication, recombination and repair]
Statistics
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PSSM-Id: 440512
Aligned: 709 rows
Threshold Bit Score: 393.649
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3TAN_A        29 ADK-AA-LVV--E---VV-----------EENY-HDA-PIVGIAVVNEHGR--FF--------------L----RPETAL 68 
WP_014807273 313 GKA-VA-LAYagE----------------GRyP--QGyKVSECVIAeGDDSlnAvd----------------ltE-TAGL 355
WP_014242994 324 DTY-LG-LDV--Q---YT-----------NLDT-RSL-DIHSLSISKNKNE--AFyi-----------------kEEQAK 364
YP_002343776 316 ESI-IA-FDT--E---TT-----------GLDT-KEA-KIVGFSFCMNENE--AFyvplthnylgvgeqI----SLQSAK 369
WP_013327153 336 ETI-VA-FDT--E---TT-----------GLDY-INN-KLVGFSFSFNDEE--AYyvpfghfylgvadqV----SKDVAK 389
NP_208261    342 ARV-FArL---------------------VLD--KEK-KVLALAFLYEDQ---GYflpl-------eeaLfspfSLEFLQ 386
WP_066744232 316 SDD-LA-Ia-----------------------P--AViLLGGFALAdREGRt-Anld---------------lsS-AEDV 351
WP_128742288  19 ASI-AA-FDF--E---TApddayrsddraALDA-HKS-HIAGISFSVAEGD--AVylplah--rigenaA----DQDAIW 81 
WP_013515406 335 DEPpMT------EatsTD-----------AL-PsLAG-EDVGLVF--EDN---AFfigm------egreYr--yTgPA-- 380
WP_011838169  19 TVL-FA-FDF--E---TSprdkwrndksaALDA-HKA-DITGISFSVSEGT--AIyvplkh--rsgrnaE----NQAAIW 81 
3TAN_A        69 AdpQFVAWL-GDETKKKSMF-DSKRAAVA-LK-W-KGIE-LC--Gv-SFDLLLAAYLLDPAQ---G---VDDVAAAAKMK 133
WP_014807273 356 E--ALIEKI-RGRKV--LLW-GYKELTTA-LR-Rp---PcAP--He-AWDGKIAYYLLHPDYa-tS---KEGLSEIKR-- 415
WP_014242994 365 P--LLEKIL-TTDTLKVATA-DYKSLLYYsL--R-NEIE-IS--Ae-VFDVVQAQFVANPGE-------KNTIESLSEKF 426
YP_002343776 370 K--AIEVIF--NHFV--IGH-NLKYDFKI-IQ-NnFDLN-LP--Qk-YADTMILAWLKNPSL-------RVNMDDLALRL 429
WP_013327153 390 Q--AMRRIF--NSKV--VGH-NIKFDLHF-VT-RfLEEK-DL--Pv-YCDSMILAWLINPES-------ALSLDKLSDKL 449
NP_208261    387 N--AFFKML-QHAQI--IGH-DLKPLLSF-LKaK-YQVP-LE--NirIQDTQILAFLKNPEK--------VGFDEVLKEY 447
WP_066744232 352 E--KFSGWS-EHGTL--TLY-GCRTLMSL--SpE---LP-LPpfEr-IRDLEIANYLLHPDR---G-----GLKGIARAI 410
WP_128742288  82 G--WLKPNFfMNSAVTKIAH-NLAFESAF-LY-A-KGIV-VQ--Ep-CYDTIAAAQLVYKNEkefRslgDCGLKTLVPEY 151
WP_013515406 381 D--ALARAL-EHASV--IATpSVQDLLRA-DA-A-WGYL-LS--Sq-WFDLSLAAYLLDPEA---R---NYTWPRLRQSL 442
WP_011838169  82 D--YLKLLF-ESKDVIKVAH-NLAFESMF-LY-A-RGIV-LQ--Kp-CYDTIAASQLTLKSKwefRslaDSGLKTLAPAL 150
3TAN_A       134 QYEAVRPDEAVygKGAkravPDE-----PVLAEHLVRKAAAIWELERPFLDELRRn--E---QDRLLVELEQPLSSILAE 203
WP_014807273 416 L------------Rq------cEm---------gLDREALSLFDIYEKLTSQFDQ---E---LNELMYKIDMPLSVVLSK 462
WP_014242994 427 LGSSIPAFEKK--Kp----lPSEne--eDLVQEISTARAHSCFRVSEFLLEELERk--E---LLNVFHDIDNKLTPVLAA 493
YP_002343776 430 FNYETLHFESLvkKGEn---FASve--lEKACKYAAEDAYITLRFYLYFLKNLET---P---LLELAKNCEFDFIKIIMM 498
WP_013327153 450 LGHEMVHFKDTvkKGEn---FSTve--lDDACVYAAEDAFITRKLYKLFLKKLELq--DathLIEEAKTVEIPFMHTLLK 522
NP_208261    448 LKEELIPHEKI--Kd-----FKtk---aE-KLELLSVELNALKRLCEYFEKGGLEe--N---LLSLAREIETPFMKVLMG 511
WP_066744232 411 -G------------GDl----------pE-----DRELALRLFDLYEFFEPDIKRy--G---LDKVMLEIDLPLSRTLAK 457
WP_128742288 152 FGEQLPSYTETv-SGLh---FDEldpqaERTVRYARSDSDYALRLYHLFNNWFDRflpK---HRFITEKIESPTAVYVGL 224
WP_013515406 443 FQ-----------DGRs--eFAEl-----AATLHPKARGLAALAYMRGIRGQVESa--H---LSTLMRDLEIPLIPVLVS 499
WP_011838169 151 CKAEMTEFSTVt-EGRf---FDElnpqdEKTVRYACADSDYTLRLYHVFNQWFDRflpK---HRTIVEEVESPTSVYVGI 223
3TAN_A       204 MEFAGVKVDTKRLEQMGKELAEQLGTVEQRIYELAGqEFN---INSPKQLGVILFEKLQLPVLKKT-KT-GYSTSADVLE 278
WP_014807273 463 MEVHGIRLNLDLLWEIKGELERTLEDVEASIDMAAGsKVN---LNSPKQVGWLLFDHLKLPVIKRT-KTg-YSTDVTVLE 537
WP_014242994 494 MEYEGVHINKAFFSEYEKELQTKLDELQASVDKFSKePVN---LNSPKQVGVLLFEELELPVGKKT-KTg-YSTDSSVLE 568
YP_002343776 499 MEENGIKLDTNALEILMKKFENEIKNLSEEIYTLCEdRFN---LNSPKQMGDILFEKLKLPSGKKG-KTg-YSTDEKVLN 573
WP_013327153 523 MEEEGIEVDTGFLEKFLVEVKETLEYLTKSIYELAGsEFN---INSTQQLGNILFEKLGLPVGKKT-KTg-YSTNEKVLS 597
NP_208261    512 MEFQGFKIDAPYFKRLEQEFKNELHVLERQILELIGvDFN---LNSPKQLSEVLYDKLGLPKNKs------HSTDEKSLL 582
WP_066744232 458 MYRTGIHADAEMLAAVEDELSHNIAAAEADIENYVGeRIN---LSSPKQVSQLLFERLMLPPIKKN-HRg-YSTDAYVLE 532
WP_128742288 225 MRYNGLPIDRPLMEQKGAEAEKKLADLRRDIAFIIG-DVSigaNASTAAFKKYLFDRLKLPKVKQTeKE-RDALDDEALI 302
WP_013515406 500 MEQAGIGVDLDAFAGFLDDVSTQLDELTRSIIRHAGePFN---IRSSQQLAAILFDKLDIKEGNKT-ATgQRSTANQVLE 575
WP_011838169 224 MKYNGILVDKSAMLKKQAEAAEKIVSIRKEIAGIIG-NVEigaNASTSAFKKYLFVDLGLPVMKTTaKH-QEAADDETMI 301
3TAN_A       279 KLAP----Y--HE----IVENILHYRQLGKLQSTYIEGLLKVVRP-DTKKVHTIFNQALTQTGRLSSTEPNLQNIPIRLE 347
WP_014807273 538 ELSRlnrpE--AL----VAKLLLDHRELSKMLSGFVQPLIDAIDP-KTGKVHTTFEHTSTGTGRLSSRDPNLQNLPAYGD 610
WP_014242994 569 DLAA----KglSE----VPALILEYREVGKILSTYVKAIPELLNE-ASGKIHTHFNQNVAATGRLSSNHPNLQNIPIRSE 639
YP_002343776 574 ILLD----K--HP----VIAKILDYRELAKLYSTYCEPLLKLALKdKNSRIYSSFLQTGTATGRLSSKDPNLQNIPAHGQ 643
WP_013327153 598 SLKD----K--HP----IIPKLLEYREVHKLYSTYIDPLLKLANEdEQHRIHTSFVQTGTATGRLSSKNPNLQNIPTRTP 667
NP_208261    583 KILD----K--HP----SIALILEYRELNKLFNTYTTPLLRLKD--KDDKIHTTFIQTGTATGRLSSHSPNLQNIPVRSP 650
WP_066744232 533 ELSK----Lp-EPlc-vVPQKIINYREESKVQTGFVQPFLKLSRE-GGGLIHSTFDHLATGTGRLASKDPNVQNMPVFGD 605
WP_128742288 303 LLKEycekN--RPelvrLFELVQEYRRWGKIKSTYIDGYLKYVNT-ATGRIHPDLLPLATETGRFASKNPNCQNMPRAGA 379
WP_013515406 576 AIRS----R--HP----IVEDILEYRMLEKLRSTYLEPLPKLVG--EDSRLHTHFNQLATATGRLSSSQPNLQNIPIRGK 643
WP_011838169 302 LLKEwcatN--RPelvrLFELVQEYRKWGKLKSTYIDGYLRFIDE-DTGRIHPDLMPLGTETGRFASRNPNMQNCPQKDN 378
3TAN_A       348 EGRKIRQAFVPSEsD-WLIFAADYSQIELRVLAHIAEDDNLMEAFRRDLDIHTKTAMDIFQVSEDEVT-------PNMRR 419
WP_014807273 611 WAKKLKEAFIPSSpD-GIFIGADYSQIELRVLAHISGDEKLREAFERGRDIHAETAAWVFGVEPEDVT-------SELRR 682
WP_014242994 640 LGRRVRKGFIAGP-G-KILLAADYSQVELRLLAHFSNDKTMIDAFKKGVDIHRRTASEIMGVPVEEVG-------SNDRS 710
YP_002343776 644 YAKDYKSCFVAKD-G-FSFISLDYSQIELRILAHFSEDEKLLNAFANDEDIHARTAIMIFGE----SN-------YETRS 710
WP_013327153 668 LGAKIRRGFVAGE-G-KKFIGIDYSQMELRLLAHFSQDPVLVNAFMHDKDIHLQTAIVLFGE---EEA-------AHKRN 735
NP_208261    651 KGLLIRKGFIASSkE-YCLLGVDYSQIELRLLAHFSQDKDLMEAFLKGRDIHLETSKALFG---EYLA-------KEKRS 719
WP_066744232 606 WADRFRACFTPRD-GeSVFVAADYSQIELRVLADLTGEEKLIQAFHDGHDVHLETASWVFGLPSGDIT-------PEQRR 677
WP_128742288 380 DDIGVRNFITAPE-G-KLLLSLDFSQIELRVGAFYCKDEKMLETYRSGGDIHAQTTSVIYKIPLEQAKdknapeyKERRT 457
WP_013515406 644 HGPRMRACFIAGP-G-AMLAAADYSQIELRVLAHFSGDPALIDAFRNDEDIHTRTAALLTDKQPQDVL-------ADERR 714
WP_011838169 379 DPIGVRKFIIAPA-G-KVLLSLDFSQIELRVGAFYCRDKRMLETYRTGGDIHAQTTSVIYRIPFEEAAdknaphyKERRT 456
3TAN_A       420 QAKAVNFGIVYGISDYGLAQNL------NISRKEAAEFIERYFESFPGVKRYMENIVQEAKQKGYVTTLLHRRRYLPDIT 493
WP_014807273 683 MAKMINFGLLYGMTPYGLASRL------GISRDEAKAIIDRYFSGFPRVKEYIEKSYEEAKNRGYSLSIFGRRRPLNEVT 756
WP_014242994 711 KAKAVNFGLMYGQSSFGLAAAL------KIPRKEAKEYITNYFERFSSVKGYLDHLKEECEKTGYAITLKGRKRYLADIH 784
YP_002343776 711 VAKSINFGLIYGMGYKTLSQNL------KIEANLAKSYIEKYFENFTSIKKYFEKVKNEAKQNGFIVTLSGRKRYF-DFE 783
WP_013327153 736 IAKTVNFGLLYGMGPKKLSDTL------GITTKEAKEIIEKYFESFHTVKAYFRSIVESSKEKGYVETLLGRRRYF-DYE 808
NP_208261    720 IAKSINFGLVYGMGSKKLSETL------NISLNEAKSYIEAYFKRFPSIKDYLNRMKEEILKTSKAFTLLGRYRVF-DFT 792
WP_066744232 678 FAKVVNFGLIYGMSAFGLAQRL------GIPRNVAAQMVDKYFSVLPKVQKYMSDSVSEAKERGYTMSHFGRIRPLSEVA 751
WP_128742288 458 IAKNCNFGTFFGLYPKGLQKTLkfkaglDVSLDECDRIIRSLKSGYPRLSRWQEETKRRAEFRKYTETWLGRRRSLPGIT 537
WP_013515406 715 NAKTINFGLIYGMGPQKLAREL------DITVNQAKEFIERYFDKLATLKAYYDTIVKDAESHGFVTTLAGRRRLLPELH 788
WP_011838169 457 IAKNCNFGVFYGLFPTGLQRTLkfkagiNPTLAECETIIQNLKSGYPGLAKWQDEVKKRAAVSCYSETWLGRRRYLLGIR 536
3TAN_A       494 SRNFNVRSFAERMAMNTPIQGSAADIIKKAMIDLNARLKEErLQAHLLLQVHDELILEAPKEEMERLCRLVPEVMEQA-- 571
WP_014807273 757 TVEGNSTAALKRVAINTPIQSSAADIAKMAMIRFDEALQKEhIDAALVLQIHDSLICECHEKDEGAVSDLLKRSMEHV-- 834
WP_014242994 785 STNRTIKANAERVAINSPIQGTAADIIKLAMINIQKVLDDKkLKSKMILQVHDELIFEVVESELEEMKTILKDGMEKV-- 862
YP_002343776 784 NAKPMQIAMYERESINSILQGSAADVIKLAMLEINKELNED---KKLILQIHDELIFEVKDDLCENFVKKTRDIMENI-- 858
WP_013327153 809 NATPMYRAAYERESVNSVFQGSVSDVIKLSMNKIHTIINEEkLQAKMLLQIHDELIFEVDEKVADELGNRFRDIMDHI-- 886
NP_208261    793 GANDYVKGNYLREGVNAIFQGSASDLLKLGMLKVSERFKNN-PSVRLLLQVHDELIFEIEEKNAPELQQEIQRILNDE-- 869
WP_066744232 752 TIDGRGNNPINRVAVNTPLQSTAADIAKVALFRFDEVLEREfPTAKTVLQIHDSIICECRRDEAEAVEKLLVKTMEAV-- 829
WP_128742288 538 STNWNVKSFAQRVAMNTPIQGTAADILKLALGRIVRGLPERs-WLCPLLQIHDELVFELPENQLKEAVLFIKTCMETQpf 616
WP_013515406 789 SRNTQLVSQARRQAVNTVIQGSAADIIKMAMVAAHKDKDLAaLGAHVILQVHDELIIEAPEASIRPAGERLKTIMQSV-- 866
WP_011838169 537 SSDWGKKSFAERCALNTPIQGTAADILKLACGRIISGLPER-LWLKPMLQIHDELVFELPEDKVDEAVVFIKECMETQpf 615
3TAN_A       572 V-TLRVPLKVDYHYGSTWYDAK 592
WP_014807273 835 I-RLSVPLEVNLKSGRSLAEV- 854
WP_014242994 863 V-SLSVPLDVDMGVGVNWFDLK 883
YP_002343776 859 V-KLKVKLKTSSSIAKNWGDLK 879
WP_013327153 887 V-ELNIPLKASLNIGDNWGELK 907
NP_208261    870 VyPLRVPLETSAFIAKRWNELK 891
WP_066744232 830 D-ILKVPLKAEPKRGLSLKEV- 849
WP_128742288 617 E-AFSVPIVADAAAGKRFGELR 637
WP_013515406 867 A-DLAVPLKVDLGLGRTWAEAH 887
WP_011838169 616 P-AFDVPIVAEASVGRNFGEMK 636
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