5NT2


Conserved Protein Domain Family
Flu_NS1

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pfam00600: Flu_NS1 
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Influenza non-structural protein (NS1)
NS1 is a homodimeric RNA-binding protein that is required for viral replication. NS1 binds polyA tails of mRNA keeping them in the nucleus. NS1 inhibits pre-mRNA splicing by tightly binding to a specific stem-bulge of U6 snRNA.
Statistics
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PSSM-Id: 366187
Aligned: 3 rows
Threshold Bit Score: 445.618
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5NT2_C   4 MDPNTVSSFQVDCFLWHVRKRVADQELGDAPFLDRLRADQASLRGRGSTLGLDIETATRAGKQIVERILKEESDEALKMT 83 
P03496   1 MDPNTVSSFQVDCFLWHVRKRVADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIETATRAGKQIVERILKEESDEALKMT 80  Influenza A virus (A/...
Q9Q0L6   1 MDSNTITSFQVDCYLWHIRKLLSMRDMCDAPFDDRLRRDQKALKGRGSTLGLDLRVATMEGKKIVEDILKSETNENLKIA 80  Influenza A virus (A/...
5NT2_C  84 MASVPASRYLTDMTLEEMSREWSMLIPKQKVAGPLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEI 163
P03496  81 MASVPASRYLTDMTLEEMSRDWSMLIPKQKVAGPLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEI 160 Influenza A virus (A/...
Q9Q0L6  81 IASSPAPRYITDMSIEEMSREWYMLMPRQKITGGLMVKMDQAIMDKRIILKANFSVLFDQLETLVSLRAFTESGAIVAEI 160 Influenza A virus (A/...
5NT2_C 164 SPLPSLPGHTAEDVKNAVGVLIGGLEANDNTVRVSETLQRFAWRSSNENGRPPLTPK 220
P03496 161 SPLPSLPGHTAEDVKNAVGVLIGGLEWNDNTVRVSETLQRFAWRSSNENGRPPLTPK 217 Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Q9Q0L6 161 FPIPSVPGHFTEDVKNAIGILIGGLEWNDNSIRASENIQRFAWGIHDENGGPSLPPK 217 Influenza A virus (A/goose/Guangdong/1/1996(...
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