6HB5,1JII,6OTJ,2JAN,6N0W


Conserved Protein Domain Family
TyrS

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COG0162: TyrS 
Tyrosyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
Tyrosyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Statistics
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PSSM-Id: 439932
Aligned: 827 rows
Threshold Bit Score: 337.391
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6HB5_A         4 SNL-------IKQLQERGLVAQVTD-EEaLAERLA-----QGPIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVA 70 
AKM81668       4 TNPq-----kIQTVLTRGVSEILPN-KD-GLSKIMt----EKKIRLYLGIDPTGAFLHLGHAVGLRKLQQFAELGHQVIL 72 
YP_003156238  18 AAPe-----aVLAALERTTDQIIGR-ED-LLDRLRe----GRPLRIKFGVDLTAPDLHLGHAVNLWMMRVLQDQGHTVIF 86 
AHB40368       4 VSTde---klINTFLERGVDSIYPSkDA-LKKKLLs----GERIKAYQGFDPSGPYLHVGHAMGIRALRILQQLGHEAIF 75 
WP_012919536   2 TDAq-----aVIDRLRRTTDTVVGE-AD-LRTRLAs----GRPLRIKYGVDCTAPELHLGHAVNLWMMRALQDLGHRVVF 70 
AKM79178       1 ------mrnnSSDILERRVAKILPN-KD-GLERLMs----KKKIRVYFGVDPTSTKLHLGHTIGLRTLQDFADAGHEAIL 68 
AKM82075       9 QTId-----kLIEDFSRTTDEVFSL-EE-FRKLLSs----GHQLRFKYGVDVTAPDLHIGHAVNLWMYRRLQELGHKIIF 77 
WP_020462693  39 LDLsdlapaeQAALIAERSQDLQPSpEA-LAARIGdaaarSRPFVAKFGIDPTGAEVHLGHAVPMLLLSRFARMGHRVVF 117
WP_045086081   1 mNLn-----yIIKTIKFGIYSILNE-KK-LIEKLKl----GKKLRIKAGFDPTTSNIHLGHIVLINKLIQFQKLGHEIQI 69 
WP_013676290  39 LDLsdlppaeQAALIAARSQQLQPSaDA-LAARIVsaaekGRPFVAKFGIDPTGAEVHLGHSVPMQILSRFQRMGHDVVF 117
6HB5_A        71 LVGGATGLIGDPSFKAAERKLNTEETVQEWVDKIRKQVAPFL--DFDcgeNSAIAANNYDWFGNMNVLTFLrDIGKHFSV 148
AKM81668      73 LVGNGTVKIGDPTGRDESRPMLDDATIEENFQEWKKQASKIL--DF----DLIEIRHNGDWLDKLNYADMV-KLMAKTTV 145
YP_003156238  87 LLGDTTSRIGDPTGRSTTRPVLTEEQIRENAESFLAQVTRVLrsEP----ELLRIRRNSEWFDEMGVPGLL-RELSLVTH 161
AHB40368      76 LVGDFTTLVGDPD-KDTARPLMTEEQIQKNMAGWKEQAAQLI--DFEg-eNPVKFMRNHEWLSKIGLADLI-KLLSNATV 150
WP_012919536  71 LLGDLTTRIGDPTGRSETRPALSPEQIELNAAAFLEQVSLVLrtDP----DVFEVRRNSEWYGAMDVATLL-GLFAHVTQ 145
AKM79178      69 LFGTGTVLVGDPSLRKEARKTISQKIIEQNIKTWEQQVKPII--DF----NKIEIKQNGDWLTKLTLKDIV-NIASKVTA 141
AKM82075      78 LIGDYTTQIGDPTGKSKTRPIIPIEEIQQNADAFIKQAMMVLydDP----NLVEIRRNSEWYDPMKAKDLL-SLMSLVTH 152
WP_020462693 118 IVGDITAKIGDPSGRSDERPALTDEDIARNLTTYRAQVTPFF--DF----ERAEFRRNGDWLREVRLPRLL-EIVSRIPV 190
WP_045086081  70 IIGDFTARIGDPTGKNIFRKSLTKEEVNLNSIKFKNNIINIF--N-----NNIKIFFNSKWMDKLSASKLI-DLSSNFSV 141
WP_013676290 118 IVGDMTAKIGDPSGRSDDRPALTDEDIEHNLATYREQVSPFF--DF----DRAHFRRNGDWLRKITLPEII-GITAQIPV 190
6HB5_A       149 NQMINKEAVKQRLNREdQGISFTEFSYNLLQGYDFACLnkqyGVVLQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLI 228
AKM81668     146 QQLIERDMFQKRLNDG-FPIFGHEIIYPLLQGYDSVVM----DVDLEIGGTDQTFNMMMGRHLQQQYNGHEKWVLTTPLI 220
YP_003156238 162 AHLVSRDMFRARLAAG-SEIAMHELIYPVLQGFDSVAL----DSDLTIVGTDQLFNEAMGRELQVKHGQRPQTVITSTVT 236
AHB40368     151 QQMIERDLFAKRLKRN-NPIGLQEFIYPLMQGFDSVAM----GVDLEIGGTDQTFNMLMGRELVKRYLGKDKYVRTNEMM 225
WP_012919536 146 AQLMARDMFRARVAAG-REIALHELSYPVLQGYDSFAM----RSDLTVVGSDQLFNEQLGRHFQQRLGAEPQVVITSTIT 220
AKM79178     142 VQLFKRESFQRRIEQG-STVWYHETMYPLLQGYDSVAM----DVDLEIGGTDQEFNMLMGRELQKKINHREKFVLITHMI 216
AKM82075     153 DRLISRDMFQKRIETG-QEIYENELVYPILQGYDSVAL----KADATVIGSDQLFNEMMGRFFQEKYGEPAQVIITTKIT 227
WP_020462693 191 SMSLQREDFRRRLDAG-HGLSLAELLYSVVMALDSVEV----DSDLEIGGIDQFLNMQMCRKVMEICGQTPEIVVATSLI 265
WP_045086081 142 ARMLERDNFYKRYKSK-YYISIQEFMYPIIQGYDSVIL----KSDIEIGGSDQIFNLLMGRNIQKKMFQDPQIIITMPIL 216
WP_013676290 191 SMSLQREDFRKRLDAG-QGLSLAELMYSIVMALDSVEI----NCDLEVGGIDQFLNMQMCRKVMEISGQVPELVVATSLI 265
6HB5_A       229 TKADG--TKFGKTEGGAVWLDPkktSPYKFYQFWINTADADVYRFLKFFTFMSIEEINALEEEDKNSG-KAPRAQYVLAE 305
AKM81668     221 EGTDG--RKMSKSFNNYVALTD---EPREMYGKLMSIKDELIIKYFEVLTDVDSVKISEMATAMQNGS-NPMEFKKKLAL 294
YP_003156238 237 PGLDGg-PKQSKSLGNYVPLCA---SPGEKFGRLMTLQDELVGTWARVYTDLPLAQCAELGRRADAGGaAARDAKLDLAE 312
AHB40368     226 EAPDA--LTMSKTKGNGINLSD---KSEVMYGKAMSYPDELITKCLRLLTDMPMEEIWEINKKIQDGE-NPMIFKKQMAH 299
WP_012919536 221 PGLDGg-PKQSKSLNNYIALTD---SPRDKFGKLMSLPDELVETYARVYTELPLGTVAALGSSAAVGGpAARDAKLKLAA 296
AKM79178     217 TGTDG--KPMSKTSGNCIWLTD---SANDMFGKIMKIRDDLMPNYFEFFTDKPTEEIKQLKQNLKQGRsDPISVKKNLAH 291
AKM82075     228 AGIDGk-GKQSKSLGNYIGLNH---SPREKFGRLMSIPDTLIIDYMKVYTDVPLDEIVKIEQDLST---DPKKYKLMLAQ 300
WP_020462693 266 EGTDGtgAKMSKSRGNYVPLTA---APGEIFGKIMSVPDRLVEPYFRALSEWRDSELAVLAARREAGTaHPMDLKKILAG 342
WP_045086081 217 IGIDGy-KKMSKSLYNSININD---NPGKIFQKIISIPDHLILKYLELLSLRPIIEIKYMIKQIIKGY-NPQIIKKILAK 291
WP_013676290 266 EGTDGtgAKMSKSKGNYVPLTA---APGEIFGKIMSVPDRLVEPYFRALSEWLDAELAVAAERVAAGTlHPMDLKKVLAG 342
6HB5_A       306 QVTRLVHGEEGLQAAKRITECLFS-GSLSalseadfeqlaqD-G-VP--MV-E-MEK------GADLMQALV-D-S-ELQ 369
AKM81668     295 IITKDLHDEVVANDAANFFAKTVQnDEMP------------E-E-SNfgSI-T-IKNikkangE-NAKSI---E-A-KPE 352
YP_003156238 313 AVVRRHDGADAARHSREEFVRVFSaGERP------------T-D-MT--PL-P-LEPg-----TRTALDLVL-A-A-RPE 366
AHB40368     300 EVVKVIKGAEEAEKAQKHFERTVQkKEIS------------D-E-DT--EVvN-ISg------IMPVQEFLKkA-L-KNS 354
WP_012919536 297 AVVTRYHGAGAAKAELEAFHRVFSdRAQP------------D-D-MP--EV-V-IGPa-----PLTALELLE-A-L-RPR 350
AKM79178     292 AIASQFHGQIKANEALHYFETVTQkKQAP------------E-N-TV--LF-Y-PSRp-----TLTSLGTVT-Q-A-ELA 345
AKM82075     301 EIVKRYHGEKVAEEEVEWFEKTFSqKQVP------------D-E-AI--PV-S-IGAd-----SASLIDILK-KcFdDEK 356
WP_020462693 343 EVTAAIHGVDAAMTARAEFVARFSrRTFA------------EvDdLP--VL-SdL--------GATVADAVR-G-L-GFA 396
WP_045086081 292 EIIKRFYGNDIAQNAHKLIGNIFNnGNLP------------I-N-IP--KI-E-LYIdn---iIIPLASVLN-I-S-KLV 347
WP_013676290 343 EVTAAIHGVDAAMKARDEFAARFSrRTFA------------EvDdLP--TV-AdL--------GVSVTEAVK-A-L-GFA 396
6HB5_A       370 PSRGQARKTIASNAITI----NGEK------QSDPEYFFKE--EERLFGRF--TLLRRGKKNYCLICWK 424
AKM81668     353 LSSTELGRRIEQGAVKIl--pSMQK------IESREEFLNL--PK---G----TKLKLGKRDWYKIETT 404
YP_003156238 367 LSRSAARRLLSGGAVTL----EDSR------LREAEEEVAV--RD---G----QVVKAGRRRWFRIEMP 416
AHB40368     355 ESASHIKRIVEQGGVEV----NGKK------VATTQIEIEF--AP---G----TLVKFGKRKYFKIEdK 404
WP_012919536 351 DSRSELRRLLRQGAVSV----GGVK------LTDAEARVEP--AG---G----TVVRSGKRTWHRVRRA 400
AKM79178     346 ESNSQAKRIIQQGGFSV----DNKK------ITNPKQQIKY--KG---G----EVIKFGKRDFRKVKIE 395
AKM82075     357 MSNNDLRRLITQNAVTI----DERK------ANDPFELIKL--SS---Sp---LNFKVGKRNWFKVTI- 406
WP_020462693 397 KSNGDVRRVAEQNGLRLvvesEEGQtqvpltPDDVREPLSavlKDRLDGRPgaVYLKVGR-KLARIE-P 463
WP_045086081 348 KNSAQAKDLLLNKRVKV----NGN-------IVDIRYNLKL-------Gn---YYIQAGKKNFAHIFIK 395
WP_013676290 397 ASNGDVRRVAQQNGLRLvveaDGEQeqlsltADDARAVLAdlvKDRLDGKTgdYFLKVGR-KLARIR-A 463
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