5JH3,6ZQ3,2ACT,6YCC,1YAL,1PPO,2CIO,1M6D,3HD3,2DC6,6CZK,2O6X


Conserved Protein Domain Family
Peptidase_C1

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pfam00112: Peptidase_C1 
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Papain family cysteine protease
Statistics
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PSSM-Id: 425470
Aligned: 157 rows
Threshold Bit Score: 183.511
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5JH3_A   9 APDSVDYRK--KG-Y-VTPVKNQGQCGSSWAFSSVGALEGQLKKKTG--KLLNLSPQNLVDCVS-E-ND----GCGGGYM 76  human
P92131  79 IPPQFDFRDeyPQ-C-VKPALDQGSCGSCWAFSAIGVFGDRRCAMGIdkEAVSYSQQHLISCSLe--NF----GCDGGDF 150 Giardia intestinalis
O61066  92 LQDRFDAGEawPKcPtITEIRDQSSCGSCWAVAAASAMSDRYCTLGg-vRDLRISAGDLMSCCDvc-----gyGCNGGYP 165 Trypanosoma cruzi
P90627  98 LPEFFDAAEhwPMcLtISEIRDQSNCGSCWAIAAVEAISDRYCTFGg-vPDRRMSTSNLLSCCFic-----glGCHGGIP 171 Leishmania major
Q03106  57 LPKVFDARSkwSGcStIGKILDQGHCGSCWAFGAVECLQDRFCIHHn--MNITLSANDLVACCG----FmcgdGCDGGYP 130 bread wheat
Q40413 100 LPQEFDARVawSNcStIGRILDQGHCGSCWAFGAVESLSDRFCIHYg--LNISLSANDLYACCG----FlcgdGCDGGYP 173 Aztec tobacco
F4HVZ1 128 LNNVLLWSTi----T-LWFWFLLGHCGSCWAFGAVESLSDRFCIKYn--LNVSLSANDVIACCGlLcGF----GCNGGFP 196 thale cress
Q94K85 103 LPKAFDARTawPQcTsIGNILDQGHCGSCWAFGAVESLSDRFCIQFg--MNISLSVNDLLACCGfRcGD----GCDGGYP 176 thale cress
Q16920  87 LPESFDARQkwSQcPsLNVIRNQGCCGSCWAISAASAMTDRWCIKSKgkEQFSFGATDMLACC-----HacgdGCKGGYL 161 yellow fever mosquito
P90850 184 LPEHFDARD--KWgPlIHPVADQGDCGSSWSVSTTAISSDRLAIISEgrINSTLSSQQLLSCNQ-HrQK----GCEGGYL 256 Caenorhabditis elegans
5JH3_A  77 TNAFQYVQKnRGIDSEDAY-------PYV-----GQEE-------------------SCMYN-PTGKA----AKCRGYRE 120 human
P92131 151 QPTWSFLTF-TGATTAec-------vKYV-----DYGHtvas-----------pcpaVCD-D-GSPIQl---YKAHGYGQ 201 Giardia intestinalis
O61066 166 EVAWEYYAV-HGIVSEyc-------qPYPfp-scAHHVnssdlspc----sgeydtpTCNSTcTdk----kiPLIKYRGN 228 Trypanosoma cruzi
P90627 172 TVAWLWWVW-VGIATEdc-------qPYPfd-pcSHHGnsekyppc---pstiydtpKCNTTcErn----emDLVKYKGS 235 Leishmania major
Q03106 131 ISAWQYFVQ-NGVVTDec-------dPYFdqvgcKHPGcepa-----------yptpVCEKKcKVQnq--vwEEKKHFSI 189 bread wheat
Q40413 174 LQAWKYFVR-KGVVTDec-------dPYFdnegcSHPGcepa-----------yptpKCHRKcVKQnl--lwSRSKHFGV 232 Aztec tobacco
F4HVZ1 197 MGAWLYFKY-HGVVTQECD-------PYF-----DNTGcshpgce------ptyptpKCERK-CVSRNql-wGESKHYGV 255 thale cress
Q94K85 177 IAAWQYFSY-SGVVTEECD-------PYF-----DNTGcshpgce------payptpKCSRKcVSDNKl--wSESKHYSV 235 thale cress
Q16920 162 GPAWQFWVE-QGVSSGGPYnsrqgchPYPid-vcDASGeea-------------dtpKCSKRcQSGYnvtdvWQDRRYGR 226 yellow fever mosquito
P90850 257 DRAWWYIRK-LGVVGDHCY-------PYV-----SGQSrepghclipkrdytnrqglRCPSG-SQDSTa---FKMTPPYK 319 Caenorhabditis elegans
5JH3_A 121 IPEG---NEKALKRAVARVGPVSVAIDASLtSFQFYSKGVYYDE--SCNSdn-----lNHAVLAVGYGIQK----GNKHW 186 human
P92131 202 VSKS----VPAIMGMLVAGGPLQTMIVVYA-DLSYYESGVYKHTygTINl-------gFHALEIVGYGTTDd---GTDYW 266 Giardia intestinalis
O61066 229 TSYIls-gEESFKRELLLNGPFEVSFSVYA-DFVAYTGGVYKHVtgVFLG--------GHAVRIVGWGELN----GEPYW 294 Trypanosoma cruzi
P90627 236 TSYSvk-gEKELMIELMTNGPLELTMQVYS-DFVGYKSGVYKHVlgDFLG--------GHAVKLVGWGTQD----GVPYW 301 Leishmania major
Q03106 190 NAYQvnsDPHDIMAEVYNNGPVEVAFTVYE-DFAHYKSGVYKHItgGVMG--------GHAVKLIGWGTSDa---GEDYW 257 bread wheat
Q40413 233 NAYMissDPHSIMTEVYKNGPVEVSFTVYE-DFAHYKSGVYKHVtgDIMG--------GHAVKLIGWGTSEd---GEDYW 300 Aztec tobacco
F4HVZ1 256 GAYRinpDPQDIMAEVYKNGPVEVAFTVYE-DFAHYKSGVYKYI--TGTKi------gGHAVKLIGWGTSDd---GEDYW 323 thale cress
Q94K85 236 STYTvksNPQDIMAEVYKNGPVEVSFTVYE-DFAHYKSGVYKHI--TGSNi------gGHAVKLIGWGTSSe---GEDYW 303 thale cress
Q16920 227 VAYSipnDEQKIMEEIYINGPVQAAFMTYQ-DLHAYKSGVYRHVwgHMAG--------GHAVKLMGWGVEN----GLKYW 293 yellow fever mosquito
P90850 320 VSSR----EEDIQTELMTNGPVQATFVVHEd-FFMYAGGVYQHSdlAAQKgassvaegYHSVRVLGWGVDHstgkPIKYW 394 Caenorhabditis elegans
5JH3_A 187 IIKNSWGENWGNKGYILMARNKNnACGIANLASFPK 222 human
P92131 267 IIKNSWGPDWGENGYFRIVRGVN-ECRIEDEIYAVY 301 Giardia intestinalis
O61066 295 KIANSWNHEWGMNGYFLIARGVD-ECGIEGSGVAGI 329 Trypanosoma cruzi
P90627 302 KVANSWNTDWGDKGYFLIQRGNN-ECKIESGGVAGI 336 Leishmania major
Q03106 258 LLANQWNRGWGDDGYFKIIRGKN-ECGIEEDVTAGM 292 bread wheat
Q40413 301 LLANQWNRGWGDDGYFKIRRGTN-ECEIEDEVVAGL 335 Aztec tobacco
F4HVZ1 324 LLANQWNRSWGDDGYFKIRRGTN-ECGIEQSVVAGL 358 thale cress
Q94K85 304 LMANQWNRGWGDDGYFMIRRGTN-ECGIEDEPVAGL 338 thale cress
Q16920 294 LVANSWGDDWGDNGFFKIVRGEN-HCGIEKDVHAGL 328 yellow fever mosquito
P90850 395 LCANSWGTQWGEDGYFKVLRGEN-HCEIESFVIGAW 429 Caenorhabditis elegans
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