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Items: 36

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
ERCC8
(G396fs +2 more)
Deletion
(frameshift variant)
Cockayne syndrome type 1
GUncertain significance
ERCC8
(E395del +2 more)
Microsatellite
(inframe_deletion)
Cockayne syndrome type 1
GUncertain significance
ERCC8
(Q322fs +2 more)
Deletion
(frameshift variant)
Cockayne syndrome type 1
GUncertain significance
ERCC8
(T376fs +2 more)
Deletion
(frameshift variant)
Cockayne syndrome type 1
GUncertain significance
ERCC8
Single nucleotide variant
(splice donor variant)
Cockayne syndrome type 1
GLikely pathogenic
ERCC8
(Y308fs +2 more)
Duplication
(frameshift variant)
Cockayne syndrome type 1
GUncertain significance
ERCC8
Single nucleotide variant
(splice acceptor variant)
Cockayne syndrome type 1
GLikely pathogenic
ERCC8
Single nucleotide variant
(splice acceptor variant)
Cockayne syndrome type 1
GLikely pathogenic
ERCC8
Single nucleotide variant
(splice acceptor variant)
not provided
+2 more
GPathogenic/Likely pathogenic
ERCC8
(T278fs +2 more)
Deletion
(frameshift variant)
Cockayne syndrome type 1
GUncertain significance
ERCC8
(V310fs +2 more)
Deletion
(frameshift variant)
Cockayne syndrome type 1
GLikely pathogenic
ERCC8
Single nucleotide variant
(splice donor variant)
not provided
+1 more
GPathogenic/Likely pathogenic
ERCC8
Single nucleotide variant
(splice acceptor variant)
Cockayne syndrome type 1
GLikely pathogenic
ERCC8
Single nucleotide variant
(splice acceptor variant)
Cockayne syndrome type 1
GLikely pathogenic
ERCC8
(D227fs +2 more)
Deletion
(frameshift variant)
not provided
+1 more
GPathogenic/Likely pathogenic
ERCC8
(R218* +2 more)
Duplication
(nonsense)
not provided
+1 more
GPathogenic/Likely pathogenic
ERCC8
(A205P +2 more)
Single nucleotide variant
(missense variant)
not provided
GPathogenic
ERCC8
(I48fs +2 more)
Duplication
(frameshift variant)
not provided
+1 more
GPathogenic/Likely pathogenic
ERCC8
(E188del +2 more)
Deletion
(inframe_deletion)
Cockayne syndrome type 1
+1 more
GUncertain significance
ERCC8
Single nucleotide variant
(splice acceptor variant)
Cockayne syndrome type 1
+1 more
GPathogenic
ERCC8
Single nucleotide variant
(splice acceptor variant)
not provided
+1 more
GLikely pathogenic
ERCC8
(A160V +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GPathogenic/Likely pathogenic
ERCC8
(A160T +1 more)
Single nucleotide variant
(missense variant +1 more)
Cockayne syndrome type 1
+2 more
GConflicting classifications of pathogenicity
ERCC8
(H148del +1 more)
Microsatellite
(inframe_deletion +1 more)
Cockayne syndrome type 1
GUncertain significance
ERCC8, ERCC8-AS1
Single nucleotide variant
(splice donor variant)
not provided
+1 more
GLikely pathogenic
ERCC8, ERCC8-AS1
(I6fs +2 more)
Deletion
(frameshift variant)
not provided
+1 more
GPathogenic
ERCC8, ERCC8-AS1
(V105fs +1 more)
Deletion
(frameshift variant +1 more)
not provided
+1 more
GPathogenic
ERCC8, ERCC8-AS1
(Y100* +1 more)
Single nucleotide variant
(nonsense +1 more)
UV-sensitive syndrome 2
+3 more
GPathogenic
ERCC8, ERCC8-AS1
(R41fs +1 more)
Indel
(frameshift variant +1 more)
not provided
+1 more
GPathogenic
ERCC8, ERCC8-AS1
Single nucleotide variant
(non-coding transcript variant +1 more)
not provided
+1 more
GLikely pathogenic
ERCC8
Single nucleotide variant
(splice donor variant)
not provided
+1 more
GPathogenic/Likely pathogenic
ERCC8
Single nucleotide variant
(splice donor variant)
not provided
+1 more
GLikely pathogenic
ERCC8, NDUFAF2
(Q5*)
Single nucleotide variant
(nonsense)
Cockayne syndrome type 1
GUncertain significance
ERCC8, NDUFAF2
(D6E)
Single nucleotide variant
(missense variant)
Mitochondrial complex I deficiency
+2 more
GUncertain significance
ERCC8, NDUFAF2
(Q37*)
Single nucleotide variant
(nonsense)
Cockayne syndrome type 1
GUncertain significance
ERCC8, NDUFAF2
(Y38*)
Single nucleotide variant
(nonsense)
Mitochondrial complex 1 deficiency, nuclear type 10
+3 more
GPathogenic
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