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Items: 26

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
PNKP
(G494D)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
PNKP
(H471L)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+2 more
GUncertain significance
PNKP
(D468fs)
Deletion
(frameshift variant)
not provided
GLikely pathogenic
PNKP
(M466T)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+2 more
GUncertain significance
PNKP
Deletion
(intron variant)
Developmental and epileptic encephalopathy, 12
+1 more
GConflicting classifications of pathogenicity
PNKP
Single nucleotide variant
(splice donor variant)
Developmental and epileptic encephalopathy, 12
+1 more
GPathogenic/Likely pathogenic
PNKP
(H459P)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
PNKP
(L454M)
Single nucleotide variant
(missense variant)
not specified
+5 more
GConflicting classifications of pathogenicity
PNKP
(Q436fs)
Deletion
(frameshift variant)
not provided
GLikely pathogenic
PNKP
Deletion
(splice donor variant)
Ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia
+4 more
GPathogenic/Likely pathogenic
PNKP
(S430fs)
Duplication
(frameshift variant)
not provided
GLikely pathogenic
PNKP
(T424fs)
Duplication
(frameshift variant)
Microcephaly, seizures, and developmental delay
+5 more
GPathogenic
PNKP
(G375R)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
PNKP
Single nucleotide variant
(splice donor variant)
Ataxia - oculomotor apraxia type 4
+6 more
GConflicting classifications of pathogenicity
PNKP
Single nucleotide variant
(synonymous variant)
not provided
+2 more
GLikely benign
PNKP
(T323M)
Single nucleotide variant
(missense variant)
Ataxia - oculomotor apraxia type 4
+4 more
GConflicting classifications of pathogenicity
PNKP
(T263S)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
PNKP
(P246H)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy, 12
+1 more
GUncertain significance
PNKP
(G244R)
Single nucleotide variant
(missense variant)
not provided
+2 more
GConflicting classifications of pathogenicity
PNKP
(S221N)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
PNKP
(T217S)
Single nucleotide variant
(missense variant)
not specified
+4 more
GConflicting classifications of pathogenicity
PNKP
(K202*)
Duplication
(nonsense)
not provided
+2 more
GPathogenic/Likely pathogenic
PNKP
(N97S)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy, 12
+5 more
GUncertain significance
PNKP
Single nucleotide variant
(synonymous variant)
Developmental and epileptic encephalopathy, 12
+1 more
GConflicting classifications of pathogenicity
PNKP
(A63V)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+4 more
GConflicting classifications of pathogenicity
PNKP
(Q50L)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
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