"Zotz-Klimas Genetics Lab, MVZ Zotz Klimas"[submitter] AND "MSH6"[gene - ClinVar

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 419112	NM_000179.3(MSH6):c.67G>C (p.Ala23Pro)	MSH6 (A23P)	Single nucleotide variant (missense variant +1 more)	Hereditary nonpolyposis colorectal neoplasms +3 more	GConflicting classifications of pathogenicity
Select item 89534	NM_000179.3(MSH6):c.467C>G (p.Ser156Ter)	MSH6 (S156*)	Single nucleotide variant (nonsense +2 more)	Lynch syndrome	GPathogenic
Select item 142970	NM_000179.3(MSH6):c.2555AGA[2] (p.Lys854del)	MSH6 (K854del +2 more)	Microsatellite (inframe_deletion)	Endometrial carcinoma +4 more	GUncertain significance
Select item 483785	NM_000179.3(MSH6):c.3928G>A (p.Glu1310Lys)	MSH6 (E1310K +2 more)	Single nucleotide variant (missense variant)	Hereditary cancer-predisposing syndrome +1 more	GConflicting classifications of pathogenicity
Select item 234901	NM_000179.3(MSH6):c.3946G>C (p.Gly1316Arg)	MSH6 (G1316R +2 more)	Single nucleotide variant (missense variant)	not provided +2 more	GConflicting classifications of pathogenicity
Select item 2562458	NM_000179.3(MSH6):c.4001+5_4001+6insAGTTA	MSH6	Insertion (intron variant)	Hereditary cancer-predisposing syndrome +1 more	GUncertain significance
Select item 976770	NM_001190274.2(FBXO11):c.2729A>G (p.Asp910Gly)	FBXO11, MSH6 (D826G +1 more)	Single nucleotide variant (missense variant)	Intellectual developmental disorder with dysmorphic facies and behavioral abnormalities +1 more	GPathogenic/Likely pathogenic

ClinVar