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Items: 42

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
NPHP4
(Q744* +2 more)
Single nucleotide variant
(nonsense +1 more)
Nephronophthisis
GPathogenic
NPHP4
(A1110V +2 more)
Single nucleotide variant
(missense variant +1 more)
Nephronophthisis
+5 more
GConflicting classifications of pathogenicity
NPHP4
(T1004fs +2 more)
Duplication
(frameshift variant +1 more)
Nephronophthisis
GPathogenic
NPHP4
(E989K +2 more)
Single nucleotide variant
(missense variant +1 more)
Nephronophthisis 4
+3 more
GConflicting classifications of pathogenicity
NPHP4
(P263fs +2 more)
Deletion
(frameshift variant +1 more)
Nephronophthisis
GLikely pathogenic
NPHP4
(Y154fs +2 more)
Microsatellite
(frameshift variant +1 more)
Nephronophthisis
GPathogenic
NPHP4
(Q410*)
Single nucleotide variant
(5 prime UTR variant +2 more)
Nephronophthisis
GPathogenic
NPHP4
(Q359*)
Single nucleotide variant
(5 prime UTR variant +2 more)
Nephronophthisis
GPathogenic
NPHP4
Indel
(5 prime UTR variant +2 more)
Nephronophthisis
GUncertain significance
IFT172
(A776V)
Single nucleotide variant
(missense variant)
Nephronophthisis
GUncertain significance
IFT172
(R432H)
Single nucleotide variant
(missense variant)
Retinitis pigmentosa 71
+2 more
GUncertain significance
NPHP1
(P186fs +1 more)
Duplication
(frameshift variant)
Inborn genetic diseases
+4 more
GPathogenic
TTC21B
(I1208V)
Single nucleotide variant
(missense variant)
Jeune thoracic dystrophy
+1 more
GUncertain significance
TTC21B, TTC21B-AS1
(L223V)
Single nucleotide variant
(missense variant)
Jeune thoracic dystrophy
+1 more
GUncertain significance
TTC21B-AS1, TTC21B
(P209L)
Single nucleotide variant
(missense variant)
Asphyxiating thoracic dystrophy 4
+7 more
GPathogenic/Likely pathogenic
IQCB1
(I301fs)
Duplication
(frameshift variant +1 more)
Retinal dystrophy
+2 more
GPathogenic
IQCB1
(C253fs)
Deletion
(frameshift variant +2 more)
Senior-Loken syndrome 5
GPathogenic
NPHP3, NPHP3-ACAD11
(P643L)
Single nucleotide variant
(missense variant)
Nephronophthisis
+1 more
GLikely pathogenic
EVC
(D95G)
Single nucleotide variant
(missense variant)
Ellis-van Creveld syndrome
+3 more
GBenign/Likely benign
CC2D2A
(E842Q +1 more)
Single nucleotide variant
(missense variant)
Nephronophthisis
GUncertain significance
CC2D2A
(R1019Q +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
NIPBL
(T914S)
Single nucleotide variant
(missense variant)
Nephronophthisis
GUncertain significance
CPLANE1
(P2144A)
Single nucleotide variant
(missense variant)
Nephronophthisis
GUncertain significance
CPLANE1
(C614R)
Single nucleotide variant
(missense variant)
Nephronophthisis
GUncertain significance
CPLANE1
Deletion
(frameshift variant)
Joubert syndrome 17
+5 more
GPathogenic/Likely pathogenic
CPLANE1
(E142K)
Single nucleotide variant
(missense variant)
not provided
+2 more
GPathogenic/Likely pathogenic
AHI1
(S749*)
Single nucleotide variant
(nonsense)
Familial aplasia of the vermis
GPathogenic
AHI1
(Q423*)
Single nucleotide variant
(nonsense)
Retinal dystrophy
+5 more
GPathogenic
RMND1
Deletion
(splice donor variant)
Nephronophthisis
GPathogenic
RMND1
(N238S +1 more)
Single nucleotide variant
(missense variant)
Combined oxidative phosphorylation defect type 11
+3 more
GConflicting classifications of pathogenicity
INVS
(W59* +1 more)
Single nucleotide variant
(nonsense +2 more)
Nephronophthisis
GPathogenic
INVS
(H164R +1 more)
Single nucleotide variant
(missense variant +2 more)
Nephronophthisis
GUncertain significance
INVS
(R899* +2 more)
Single nucleotide variant
(nonsense +1 more)
Nephronophthisis
+2 more
GPathogenic
CEP164
(D1354N +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
CEP290
(E1656fs)
Microsatellite
(frameshift variant)
Bardet-Biedl syndrome 14
+4 more
GPathogenic
CEP290
(W7C)
Single nucleotide variant
(missense variant)
Joubert syndrome 5
+3 more
GPathogenic
KIF7
(Q834R)
Single nucleotide variant
(missense variant)
not specified
+2 more
GConflicting classifications of pathogenicity
IFT140
(P726A)
Single nucleotide variant
(missense variant)
Saldino-Mainzer syndrome
+2 more
GConflicting classifications of pathogenicity
IFT140, LOC105371046
(G212R)
Single nucleotide variant
(missense variant)
not provided
+3 more
GPathogenic/Likely pathogenic
MKKS
(K198fs)
Deletion
(frameshift variant)
Nephronophthisis
GPathogenic
MKKS
(Y37C)
Single nucleotide variant
(missense variant)
Bardet-Biedl syndrome
+5 more
GPathogenic/Likely pathogenic
NPHP1
Deletion
Nephronophthisis
GLikely pathogenic
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