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GRCh37/hg19 Yp11.32-q12(chrY:21267-59349649)x2 AND See cases

Germline classification:
Pathogenic (1 submission)
Last evaluated:
Jan 20, 2016
Review status:
1 star out of maximum of 4 stars
criteria provided, single submitter
Somatic classification
of clinical impact:
None
Review status:
(0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided
Somatic classification
of oncogenicity:
None
Review status:
(0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided
Record status:
current
Accession:
RCV000239787.2

Allele description [Variation Report for GRCh37/hg19 Yp11.32-q12(chrY:21267-59349649)x2]

GRCh37/hg19 Yp11.32-q12(chrY:21267-59349649)x2

Genes:
  • DDX3Y:DEAD-box helicase 3 Y-linked [Gene - OMIM - HGNC]
  • PRORY:PRORY Y-linked lncRNA [Gene - HGNC]
  • PRY2:PTPN13 like Y-linked 2 [Gene - OMIM - HGNC]
  • PRY:PTPN13 like Y-linked [Gene - OMIM - HGNC]
  • RBMY1A1:RNA binding motif protein Y-linked family 1 member A1 [Gene - OMIM - HGNC]
  • RBMY1B:RNA binding motif protein Y-linked family 1 member B [Gene - HGNC]
  • RBMY1D:RNA binding motif protein Y-linked family 1 member D [Gene - HGNC]
  • RBMY1E:RNA binding motif protein Y-linked family 1 member E [Gene - HGNC]
  • RBMY1F:RNA binding motif protein Y-linked family 1 member F [Gene - HGNC]
  • RBMY1J:RNA binding motif protein Y-linked family 1 member J [Gene - HGNC]
  • TGIF2LY:TGFB induced factor homeobox 2 like Y-linked [Gene - OMIM - HGNC]
  • WASIR1:WASH and IL9R antisense RNA 1 [Gene - HGNC]
  • AMELY:amelogenin Y-linked [Gene - OMIM - HGNC]
  • BPY2:basic charge Y-linked 2 [Gene - OMIM - HGNC]
  • BPY2B:basic charge Y-linked 2B [Gene - HGNC]
  • BPY2C:basic charge Y-linked 2C [Gene - HGNC]
  • CDY1:chromodomain Y-linked 1 [Gene - OMIM - HGNC]
  • CDY2A:chromodomain Y-linked 2A [Gene - OMIM - HGNC]
  • DAZ1:deleted in azoospermia 1 [Gene - OMIM - HGNC]
  • DAZ2:deleted in azoospermia 2 [Gene - OMIM - HGNC]
  • DAZ3:deleted in azoospermia 3 [Gene - OMIM - HGNC]
  • DAZ4:deleted in azoospermia 4 [Gene - OMIM - HGNC]
  • EIF1AY:eukaryotic translation initiation factor 1A Y-linked [Gene - OMIM - HGNC]
  • FAM197Y1P:family with sequence similarity 197 Y-linked member 1, pseudogene [Gene - HGNC]
  • FAM197Y10:family with sequence similarity 197 Y-linked member 10 [Gene - HGNC]
  • FAM197Y9:family with sequence similarity 197 Y-linked member 9 [Gene - HGNC]
  • HSFY1:heat shock transcription factor Y-linked 1 [Gene - OMIM - HGNC]
  • HSFY2:heat shock transcription factor Y-linked 2 [Gene - HGNC]
  • KDM5D:lysine demethylase 5D [Gene - OMIM - HGNC]
  • NLGN4Y:neuroligin 4 Y-linked [Gene - OMIM - HGNC]
  • PCDH11Y:protocadherin 11 Y-linked [Gene - OMIM - HGNC]
  • RPS4Y1:ribosomal protein S4 Y-linked 1 [Gene - OMIM - HGNC]
  • RPS4Y2:ribosomal protein S4 Y-linked 2 [Gene - OMIM - HGNC]
  • SRY:sex determining region Y [Gene - OMIM - HGNC]
  • TSPY10:testis specific protein Y-linked 10 [Gene - HGNC]
  • TSPY1:testis specific protein Y-linked 1 [Gene - OMIM - HGNC]
  • TSPY2:testis specific protein Y-linked 2 [Gene - HGNC]
  • TSPY3:testis specific protein Y-linked 3 [Gene - HGNC]
  • TSPY4:testis specific protein Y-linked 4 [Gene - HGNC]
  • TSPY8:testis specific protein Y-linked 8 [Gene - HGNC]
  • TTTY10:testis-specific transcript, Y-linked 10 [Gene - HGNC]
  • TTTY11:testis-specific transcript, Y-linked 11 [Gene - HGNC]
  • TTTY12:testis-specific transcript, Y-linked 12 [Gene - HGNC]
  • TTTY13:testis-specific transcript, Y-linked 13 [Gene - HGNC]
  • TTTY13B:testis-specific transcript, Y-linked 13B [Gene - HGNC]
  • TTTY14:testis-specific transcript, Y-linked 14 [Gene - HGNC]
  • TTTY15:testis-specific transcript, Y-linked 15 [Gene - HGNC]
  • TTTY16:testis-specific transcript, Y-linked 16 [Gene - HGNC]
  • TTTY17A:testis-specific transcript, Y-linked 17A [Gene - OMIM - HGNC]
  • TTTY17B:testis-specific transcript, Y-linked 17B [Gene - HGNC]
  • TTTY17C:testis-specific transcript, Y-linked 17C [Gene - HGNC]
  • TTTY18:testis-specific transcript, Y-linked 18 [Gene - HGNC]
  • TTTY19:testis-specific transcript, Y-linked 19 [Gene - HGNC]
  • TTTY1:testis-specific transcript, Y-linked 1 [Gene - HGNC]
  • TTTY1B:testis-specific transcript, Y-linked 1B [Gene - HGNC]
  • TTTY20:testis-specific transcript, Y-linked 20 [Gene - HGNC]
  • TTTY21:testis-specific transcript, Y-linked 21 [Gene - HGNC]
  • TTTY21B:testis-specific transcript, Y-linked 21B [Gene - HGNC]
  • TTTY22:testis-specific transcript, Y-linked 22 [Gene - HGNC]
  • TTTY23:testis-specific transcript, Y-linked 23 [Gene - HGNC]
  • TTTY23B:testis-specific transcript, Y-linked 23B [Gene - HGNC]
  • TTTY2:testis-specific transcript, Y-linked 2 [Gene - HGNC]
  • TTTY2B:testis-specific transcript, Y-linked 2B [Gene - HGNC]
  • TTTY3:testis-specific transcript, Y-linked 3 [Gene - OMIM - HGNC]
  • TTTY3B:testis-specific transcript, Y-linked 3B [Gene - HGNC]
  • TTTY4:testis-specific transcript, Y-linked 4 [Gene - OMIM - HGNC]
  • TTTY4B:testis-specific transcript, Y-linked 4B [Gene - HGNC]
  • TTTY4C:testis-specific transcript, Y-linked 4C [Gene - HGNC]
  • TTTY5:testis-specific transcript, Y-linked 5 [Gene - OMIM - HGNC]
  • TTTY6:testis-specific transcript, Y-linked 6 [Gene - OMIM - HGNC]
  • TTTY6B:testis-specific transcript, Y-linked 6B [Gene - HGNC]
  • TTTY7:testis-specific transcript, Y-linked 7 [Gene - HGNC]
  • TTTY7B:testis-specific transcript, Y-linked 7B [Gene - HGNC]
  • TTTY8:testis-specific transcript, Y-linked 8 [Gene - HGNC]
  • TTTY8B:testis-specific transcript, Y-linked 8B [Gene - HGNC]
  • TTTY9A:testis-specific transcript, Y-linked 9A [Gene - HGNC]
  • TTTY9B:testis-specific transcript, Y-linked 9B [Gene - HGNC]
  • TMSB4Y:thymosin beta 4 Y-linked [Gene - OMIM - HGNC]
  • TBL1Y:transducin beta like 1 Y-linked [Gene - OMIM - HGNC]
  • USP9Y:ubiquitin specific peptidase 9 Y-linked [Gene - OMIM - HGNC]
  • UTY:ubiquitously transcribed tetratricopeptide repeat containing, Y-linked [Gene - OMIM - HGNC]
  • VCY1B:variable charge Y-linked 1B [Gene - OMIM - HGNC]
  • VCY:variable charge Y-linked [Gene - OMIM - HGNC]
  • ZFY:zinc finger protein Y-linked [Gene - OMIM - HGNC]
Variant type:
copy number gain
Cytogenetic location:
Yp11.32-q12
Genomic location:
ChrY: 21267 - 59349649 (on Assembly GRCh37)
Preferred name:
GRCh37/hg19 Yp11.32-q12(chrY:21267-59349649)x2
HGVS:

    Condition(s)

    Name:
    See cases [See the Variation display for details]
    Identifiers:

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    Assertion and evidence details

    Submission AccessionSubmitterReview Status
    (Assertion method)
    Clinical Significance
    (Last evaluated)
    OriginMethodCitations
    SCV000298475GeneDx
    criteria provided, single submitter

    (GeneDx Variant Classification (06012015))
    Pathogenic
    (Jan 20, 2016)
    unknownclinical testing

    Citation Link

    Summary from all submissions

    EthnicityOriginAffectedIndividualsFamiliesChromosomes testedNumber TestedFamily historyMethod
    not providedunknownyesnot providednot providednot providednot providednot providedclinical testing

    Details of each submission

    From GeneDx, SCV000298475.3

    #EthnicityIndividualsChromosomes TestedFamily HistoryMethodCitations
    1not providednot providednot providednot providedclinical testingnot provided
    #SampleMethodObservation
    OriginAffectedNumber testedTissuePurposeMethodIndividualsAllele frequencyFamiliesCo-occurrences
    1unknownyesnot providednot providednot providednot providednot providednot providednot provided

    Last Updated: Jul 8, 2023