ClinVar

NM_000546.6(TP53):c.395A>T (p.Lys132Met)

Gene:

TP53:tumor protein p53 [Gene - OMIM - HGNC]

Variant type:

single nucleotide variant

Cytogenetic location:

17p13.1

Genomic location:

• Chr17: 7675217 (on Assembly GRCh38)
• Chr17: 7578535 (on Assembly GRCh37)

Preferred name:

NM_000546.6(TP53):c.395A>T (p.Lys132Met)

HGVS:

• NC_000017.11:g.7675217T>A
• NG_017013.2:g.17334A>T
• NM_000546.6:c.395A>TMANE SELECT
• NM_001126112.3:c.395A>T
• NM_001126113.3:c.395A>T
• NM_001126114.3:c.395A>T
• NM_001126115.2:c.-2A>T
• NM_001126116.2:c.-2A>T
• NM_001126117.2:c.-2A>T
• NM_001126118.2:c.278A>T
• NM_001276695.3:c.278A>T
• NM_001276696.3:c.278A>T
• NM_001276697.3:c.-83A>T
• NM_001276698.3:c.-83A>T
• NM_001276699.3:c.-83A>T
• NM_001276760.3:c.278A>T
• NM_001276761.3:c.278A>T
• NM_001407262.1:c.395A>T
• NM_001407263.1:c.278A>T
• NM_001407264.1:c.395A>T
• NM_001407265.1:c.278A>T
• NM_001407266.1:c.395A>T
• NM_001407267.1:c.278A>T
• NM_001407268.1:c.395A>T
• NM_001407269.1:c.278A>T
• NM_001407270.1:c.395A>T
• NM_001407271.1:c.278A>T
• NP_000537.3:p.Lys132Met
• NP_000537.3:p.Lys132Met
• NP_001119584.1:p.Lys132Met
• NP_001119584.1:p.Lys132Met
• NP_001119585.1:p.Lys132Met
• NP_001119585.1:p.Lys132Met
• NP_001119586.1:p.Lys132Met
• NP_001119586.1:p.Lys132Met
• NP_001119590.1:p.Lys93Met
• NP_001119590.1:p.Lys93Met
• NP_001263624.1:p.Lys93Met
• NP_001263625.1:p.Lys93Met
• NP_001263689.1:p.Lys93Met
• NP_001263690.1:p.Lys93Met
• NP_001394191.1:p.Lys132Met
• NP_001394192.1:p.Lys93Met
• NP_001394193.1:p.Lys132Met
• NP_001394194.1:p.Lys93Met
• NP_001394195.1:p.Lys132Met
• NP_001394196.1:p.Lys93Met
• NP_001394197.1:p.Lys132Met
• NP_001394198.1:p.Lys93Met
• NP_001394199.1:p.Lys132Met
• NP_001394200.1:p.Lys93Met
• LRG_321t1:c.395A>T
• LRG_321t2:c.395A>T
• LRG_321t3:c.395A>T
• LRG_321t4:c.395A>T
• LRG_321t5:c.-2A>T
• LRG_321t6:c.-2A>T
• LRG_321t7:c.-2A>T
• LRG_321t8:c.278A>T
• LRG_321:g.17334A>T
• LRG_321:p.Lys132Met
• LRG_321p1:p.Lys132Met
• LRG_321p3:p.Lys132Met
• LRG_321p4:p.Lys132Met
• LRG_321p8:p.Lys93Met
• NC_000017.10:g.7578535T>A
• NM_000546.4:c.395A>T
• NM_000546.5:c.395A>T
• NM_001126112.2:c.395A>T
• NM_001126113.2:c.395A>T
• NM_001126114.2:c.395A>T
• NM_001126115.1:c.-2A>T
• NM_001126116.1:c.-2A>T
• NM_001126117.1:c.-2A>T
• NM_001126118.1:c.278A>T
• NR_176326.1:n.537A>T

This HGVS expression did not pass validation

Protein change:

K132M

Links:

dbSNP: rs1057519996

NCBI 1000 Genomes Browser:

rs1057519996

Molecular consequence:

• NM_001126115.2:c.-2A>T - 5 prime UTR variant - [Sequence Ontology: SO:0001623]
• NM_001126116.2:c.-2A>T - 5 prime UTR variant - [Sequence Ontology: SO:0001623]
• NM_001126117.2:c.-2A>T - 5 prime UTR variant - [Sequence Ontology: SO:0001623]
• NM_001276697.3:c.-83A>T - 5 prime UTR variant - [Sequence Ontology: SO:0001623]
• NM_001276698.3:c.-83A>T - 5 prime UTR variant - [Sequence Ontology: SO:0001623]
• NM_001276699.3:c.-83A>T - 5 prime UTR variant - [Sequence Ontology: SO:0001623]
• NM_000546.6:c.395A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001126112.3:c.395A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001126113.3:c.395A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001126114.3:c.395A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001126118.2:c.278A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001276695.3:c.278A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001276696.3:c.278A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001276760.3:c.278A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001276761.3:c.278A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001407262.1:c.395A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001407263.1:c.278A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001407264.1:c.395A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001407265.1:c.278A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001407266.1:c.395A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001407267.1:c.278A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001407268.1:c.395A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001407269.1:c.278A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001407270.1:c.395A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001407271.1:c.278A>T - missense variant - [Sequence Ontology: SO:0001583]
• NR_176326.1:n.537A>T - non-coding transcript variant - [Sequence Ontology: SO:0001619]