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GRCh37/hg19 Yq11.222-12(chrY:21035530-59336737)x0 AND not provided

Germline classification:
Pathogenic (1 submission)
Last evaluated:
Jul 30, 2018
Review status:
(0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided
Somatic classification
of clinical impact:
None
Review status:
(0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided
Somatic classification
of oncogenicity:
None
Review status:
(0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided
Record status:
current
Accession:
RCV000845979.2

Allele description [Variation Report for GRCh37/hg19 Yq11.222-12(chrY:21035530-59336737)x0]

GRCh37/hg19 Yq11.222-12(chrY:21035530-59336737)x0

Genes:
  • PRORY:PRORY Y-linked lncRNA [Gene - HGNC]
  • PRY2:PTPN13 like Y-linked 2 [Gene - OMIM - HGNC]
  • PRY:PTPN13 like Y-linked [Gene - OMIM - HGNC]
  • RBMY1A1:RNA binding motif protein Y-linked family 1 member A1 [Gene - OMIM - HGNC]
  • RBMY1B:RNA binding motif protein Y-linked family 1 member B [Gene - HGNC]
  • RBMY1D:RNA binding motif protein Y-linked family 1 member D [Gene - HGNC]
  • RBMY1E:RNA binding motif protein Y-linked family 1 member E [Gene - HGNC]
  • RBMY1F:RNA binding motif protein Y-linked family 1 member F [Gene - HGNC]
  • RBMY1J:RNA binding motif protein Y-linked family 1 member J [Gene - HGNC]
  • BPY2:basic charge Y-linked 2 [Gene - OMIM - HGNC]
  • BPY2B:basic charge Y-linked 2B [Gene - HGNC]
  • BPY2C:basic charge Y-linked 2C [Gene - HGNC]
  • CDY1:chromodomain Y-linked 1 [Gene - OMIM - HGNC]
  • DAZ1:deleted in azoospermia 1 [Gene - OMIM - HGNC]
  • DAZ2:deleted in azoospermia 2 [Gene - OMIM - HGNC]
  • DAZ3:deleted in azoospermia 3 [Gene - OMIM - HGNC]
  • DAZ4:deleted in azoospermia 4 [Gene - OMIM - HGNC]
  • EIF1AY:eukaryotic translation initiation factor 1A Y-linked [Gene - OMIM - HGNC]
  • FAM197Y10:family with sequence similarity 197 Y-linked member 10 [Gene - HGNC]
  • KDM5D:lysine demethylase 5D [Gene - OMIM - HGNC]
  • RPS4Y2:ribosomal protein S4 Y-linked 2 [Gene - OMIM - HGNC]
  • TTTY10:testis-specific transcript, Y-linked 10 [Gene - HGNC]
  • TTTY13:testis-specific transcript, Y-linked 13 [Gene - HGNC]
  • TTTY14:testis-specific transcript, Y-linked 14 [Gene - HGNC]
  • TTTY17A:testis-specific transcript, Y-linked 17A [Gene - OMIM - HGNC]
  • TTTY17B:testis-specific transcript, Y-linked 17B [Gene - HGNC]
  • TTTY17C:testis-specific transcript, Y-linked 17C [Gene - HGNC]
  • TTTY3:testis-specific transcript, Y-linked 3 [Gene - OMIM - HGNC]
  • TTTY3B:testis-specific transcript, Y-linked 3B [Gene - HGNC]
  • TTTY4:testis-specific transcript, Y-linked 4 [Gene - OMIM - HGNC]
  • TTTY4B:testis-specific transcript, Y-linked 4B [Gene - HGNC]
  • TTTY4C:testis-specific transcript, Y-linked 4C [Gene - HGNC]
  • TTTY5:testis-specific transcript, Y-linked 5 [Gene - OMIM - HGNC]
  • TTTY6:testis-specific transcript, Y-linked 6 [Gene - OMIM - HGNC]
  • TTTY6B:testis-specific transcript, Y-linked 6B [Gene - HGNC]
Variant type:
copy number loss
Cytogenetic location:
Yq11.222-12
Genomic location:
ChrY: 21035530 - 59336737 (on Assembly GRCh37)
Preferred name:
GRCh37/hg19 Yq11.222-12(chrY:21035530-59336737)x0
HGVS:
NC_000024.9:g.(?_21035530)_(59336737_?)del

Condition(s)

Synonyms:
none provided
Identifiers:
MedGen: CN517202

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Assertion and evidence details

Submission AccessionSubmitterReview Status
(Assertion method)
Clinical Significance
(Last evaluated)
OriginMethodCitations
SCV000988100Bionano Laboratories
no assertion criteria provided
Pathogenic
(Jul 30, 2018)
unknownclinical testing

Summary from all submissions

EthnicityOriginAffectedIndividualsFamiliesChromosomes testedNumber TestedFamily historyMethod
not providedunknownunknownnot providednot providednot providednot providednot providedclinical testing

Details of each submission

From Bionano Laboratories, SCV000988100.1

#EthnicityIndividualsChromosomes TestedFamily HistoryMethodCitations
1not providednot providednot providednot providedclinical testingnot provided
#SampleMethodObservation
OriginAffectedNumber testedTissuePurposeMethodIndividualsAllele frequencyFamiliesCo-occurrences
1unknownunknownnot providedBuccalnot providednot providednot providednot providednot provided

Last Updated: Jul 8, 2023