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GRCh37/hg19 Yq11.222-11.23(chrY:21035824-28799654)x0 AND not provided

Germline classification:
Pathogenic (1 submission)
Review status:
1 star out of maximum of 4 stars
criteria provided, single submitter
Somatic classification
of clinical impact:
None
Review status:
(0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided
Somatic classification
of oncogenicity:
None
Review status:
(0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided
Record status:
current
Accession:
RCV004442771.1

Allele description [Variation Report for GRCh37/hg19 Yq11.222-11.23(chrY:21035824-28799654)x0]

GRCh37/hg19 Yq11.222-11.23(chrY:21035824-28799654)x0

Genes:
  • PRORY:PRORY Y-linked lncRNA [Gene - HGNC]
  • PRY2:PTPN13 like Y-linked 2 [Gene - OMIM - HGNC]
  • PRY:PTPN13 like Y-linked [Gene - OMIM - HGNC]
  • RBMY1A1:RNA binding motif protein Y-linked family 1 member A1 [Gene - OMIM - HGNC]
  • RBMY1B:RNA binding motif protein Y-linked family 1 member B [Gene - HGNC]
  • RBMY1D:RNA binding motif protein Y-linked family 1 member D [Gene - HGNC]
  • RBMY1E:RNA binding motif protein Y-linked family 1 member E [Gene - HGNC]
  • RBMY1F:RNA binding motif protein Y-linked family 1 member F [Gene - HGNC]
  • RBMY1J:RNA binding motif protein Y-linked family 1 member J [Gene - HGNC]
  • BPY2:basic charge Y-linked 2 [Gene - OMIM - HGNC]
  • BPY2B:basic charge Y-linked 2B [Gene - HGNC]
  • BPY2C:basic charge Y-linked 2C [Gene - HGNC]
  • CDY1:chromodomain Y-linked 1 [Gene - OMIM - HGNC]
  • DAZ1:deleted in azoospermia 1 [Gene - OMIM - HGNC]
  • DAZ2:deleted in azoospermia 2 [Gene - OMIM - HGNC]
  • DAZ3:deleted in azoospermia 3 [Gene - OMIM - HGNC]
  • DAZ4:deleted in azoospermia 4 [Gene - OMIM - HGNC]
  • EIF1AY:eukaryotic translation initiation factor 1A Y-linked [Gene - OMIM - HGNC]
  • FAM197Y10:family with sequence similarity 197 Y-linked member 10 [Gene - HGNC]
  • KDM5D:lysine demethylase 5D [Gene - OMIM - HGNC]
  • RPS4Y2:ribosomal protein S4 Y-linked 2 [Gene - OMIM - HGNC]
  • TTTY10:testis expressed transcript, Y-linked 10 [Gene - HGNC]
  • TTTY13:testis expressed transcript, Y-linked 13 [Gene - HGNC]
  • TTTY14:testis expressed transcript, Y-linked 14 [Gene - HGNC]
  • TTTY17A:testis expressed transcript, Y-linked 17A [Gene - OMIM - HGNC]
  • TTTY17B:testis expressed transcript, Y-linked 17B [Gene - HGNC]
  • TTTY17C:testis expressed transcript, Y-linked 17C [Gene - HGNC]
  • TTTY3:testis expressed transcript, Y-linked 3 [Gene - OMIM - HGNC]
  • TTTY3B:testis expressed transcript, Y-linked 3B [Gene - HGNC]
  • TTTY4:testis expressed transcript, Y-linked 4 [Gene - OMIM - HGNC]
  • TTTY4B:testis expressed transcript, Y-linked 4B [Gene - HGNC]
  • TTTY4C:testis expressed transcript, Y-linked 4C [Gene - HGNC]
  • TTTY5:testis expressed transcript, Y-linked 5 [Gene - OMIM - HGNC]
  • TTTY6:testis expressed transcript, Y-linked 6 [Gene - OMIM - HGNC]
  • TTTY6B:testis expressed transcript, Y-linked 6B [Gene - HGNC]
Variant type:
copy number loss
Cytogenetic location:
Yq11.222-11.23
Genomic location:
ChrY: 21035824 - 28799654 (on Assembly GRCh37)
Preferred name:
GRCh37/hg19 Yq11.222-11.23(chrY:21035824-28799654)x0
HGVS:

    Condition(s)

    Synonyms:
    none provided
    Identifiers:
    MedGen: C3661900

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    Assertion and evidence details

    Submission AccessionSubmitterReview Status
    (Assertion method)
    Clinical Significance
    (Last evaluated)
    OriginMethodCitations
    SCV004934009Prenatal Diagnosis Center, Urumqi Maternal and Child Health Care Hospital
    criteria provided, single submitter

    (ACMG/ClinGen CNV Guidelines, 2019)
    Pathogenicunknownclinical testing

    Summary from all submissions

    EthnicityOriginAffectedIndividualsFamiliesChromosomes testedNumber TestedFamily historyMethod
    Asianunknownunknownnot providednot providednot providednot providednot providedclinical testing

    Details of each submission

    From Prenatal Diagnosis Center, Urumqi Maternal and Child Health Care Hospital, SCV004934009.1

    #EthnicityIndividualsChromosomes TestedFamily HistoryMethodCitations
    1Asiannot providednot providednot providedclinical testingnot provided
    #SampleMethodObservation
    OriginAffectedNumber testedTissuePurposeMethodIndividualsAllele frequencyFamiliesCo-occurrences
    1unknownunknownnot providednot provideddiscoverynot providednot providednot providednot provided

    Last Updated: May 7, 2024