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ClinVar submissions

This page summarizes submissions and properties of submissions (assertion criteria, genes, unique variation records), represented in ClinVar.

Follow this link to review all submitters and the summary of their contributions. We acknowledge their support.

Submission overview

Category of analysis Current total (Dec 23, 2024)
Records submitted4772956
Records with assertion criteria4344859
Records with a classification4739953
Records with a germline classification4739227
Records with a somatic classification726
Total genes represented92268
Unique variation records3118495
Unique variation records with classifications3106946
Unique variation records with germline classifications3106617
Unique variation records with somatic classifications714
Unique variation records with assertion criteria2974126
Unique variation records with practice guidelines (4 stars)663
Unique variation records from expert panels (3 stars)18185
Unique variation records with assertion criteria, multiple submitters, and no conflicts (2 stars)507369
Unique variation records with assertion criteria (1 star)2319059
Unique variation records with assertion criteria and a conflict (1 star)128850
Unique variation records with conflicting classifications129253
Genes with variants specific to one gene17545
Genes with variants specific to one protein-coding gene17345
Genes included in a variant spanning more than one gene92608
Variants affecting overlapping genes33319
Total submitters2965