Department of Clinical Genetics (Copenhagen University Hospital, Rigshospitalet), MGL_KC
General information
Department of Clinical Genetics, MGL_KC
Copenhagen University Hospital, Rigshospitalet
Glostrup
Hovedstaden
Denmark - DK-2600
http://www.rigshospitalet.dk/
Organization ID: 1147
Copenhagen University Hospital, Rigshospitalet
Glostrup
Hovedstaden
Denmark - DK-2600
http://www.rigshospitalet.dk/
Organization ID: 1147
Personnel
- Karen Gronskov, Principal Investigator
Phone: +45 43260156
Email: Karen.Groenskov@regionh.dk - Thomas v. O. Hansen, Principal Investigator
Phone: +45 35454062
Email: Thomas.Van.Overeem.Hansen@regionh.dk
Assertion criteria
Level: Assertion criteria provided
Summary of submissions to ClinVar
Total submissions: 915
Gene
Gene | Submissions | Last Updated |
---|---|---|
ABCA4 | 79 | Dec 5, 2018 |
ACO2 | 1 | May 2, 2022 |
ACTB | 1 | May 2, 2022 |
ACVRL1 | 1 | May 2, 2022 |
ADCY5 | 1 | May 2, 2022 |
ADGRA3 | 1 | Dec 5, 2018 |
ADGRV1 | 2 | Dec 5, 2018 |
ADPRS | 2 | May 2, 2022 |
AIPL1 | 5 | Dec 5, 2018 |
ALMS1 | 1 | Dec 5, 2018 |
ANKRD11 | 7 | May 2, 2022 |
APC | 1 | Jun 22, 2023 |
AQP2 | 1 | May 2, 2022 |
AQP5-AS1 | 1 | May 2, 2022 |
ARID1B | 2 | May 2, 2022 |
ARID2 | 1 | May 2, 2022 |
ASPM | 1 | May 2, 2022 |
ASXL3 | 1 | May 2, 2022 |
ATM | 3 | Mar 21, 2024 |
B4GALT7 | 2 | May 2, 2022 |
B9D1 | 1 | May 2, 2022 |
BAP1 | 1 | Jun 27, 2023 |
BBS1 | 8 | Dec 5, 2018 |
BBS10 | 2 | Dec 5, 2018 |
BBS12 | 2 | Dec 5, 2018 |
BBS2 | 4 | Dec 5, 2018 |
BBS4 | 1 | Dec 5, 2018 |
BBS5 | 1 | Dec 5, 2018 |
BBS7 | 1 | Dec 5, 2018 |
BBS9 | 2 | Dec 5, 2018 |
BCL11A | 1 | May 2, 2022 |
BCOR | 1 | May 2, 2022 |
BEST1 | 19 | Dec 5, 2018 |
BICD2 | 1 | May 2, 2022 |
BLOC1S1-RDH5 | 1 | Dec 5, 2018 |
BMPR1B | 1 | May 2, 2022 |
BMPR2 | 1 | May 2, 2022 |
BRCA1 | 54 | May 27, 2024 |
BRCA2 | 73 | May 27, 2024 |
C10orf105 | 1 | Dec 5, 2018 |
CA4 | 1 | Dec 5, 2018 |
CABP4 | 5 | Dec 5, 2018 |
CACNA1A | 1 | Oct 5, 2022 |
CACNA1F | 7 | Dec 5, 2018 |
CACNA2D4 | 1 | Dec 5, 2018 |
CACNG2 | 1 | May 2, 2022 |
CAMTA1 | 1 | May 2, 2022 |
CAPN3 | 1 | May 6, 2020 |
CCDC22 | 1 | May 2, 2022 |
CDH23 | 7 | Dec 5, 2018 |
CDH23-AS1 | 1 | Dec 5, 2018 |
CDH3 | 1 | Dec 5, 2018 |
CDH3-AS1 | 1 | Dec 5, 2018 |
CDHR1 | 3 | Dec 5, 2018 |
CDK13 | 1 | May 2, 2022 |
CEP152 | 1 | May 2, 2022 |
CEP290 | 9 | Dec 5, 2018 |
CERKL | 4 | Dec 5, 2018 |
CHD8 | 1 | May 2, 2022 |
CHM | 2 | Dec 5, 2018 |
CHRNG | 2 | May 2, 2022 |
CLCN4 | 2 | May 2, 2022 |
CLRN1 | 1 | Dec 5, 2018 |
CNGA1 | 3 | Dec 5, 2018 |
CNGB1 | 11 | Dec 5, 2018 |
CNGB3 | 7 | Dec 5, 2018 |
CNKSR2 | 2 | May 2, 2022 |
CNNM4 | 1 | Dec 5, 2018 |
CNPY2 | 1 | May 2, 2022 |
CNTNAP1 | 2 | May 2, 2022 |
COL11A1 | 1 | May 2, 2022 |
COL12A1 | 1 | May 2, 2022 |
COL1A1 | 1 | May 2, 2022 |
COL27A1 | 1 | May 2, 2022 |
COL2A1 | 1 | May 2, 2022 |
COL4A1 | 2 | May 2, 2022 |
COL4A2 | 2 | May 2, 2022 |
COL4A2-AS2 | 1 | May 2, 2022 |
COL4A5 | 1 | May 2, 2022 |
COL6A1 | 1 | Feb 15, 2023 |
COL6A2 | 1 | May 2, 2022 |
COL6A3 | 1 | May 2, 2022 |
COMP | 1 | May 2, 2022 |
COQ4 | 2 | May 2, 2022 |
CRB1 | 17 | Dec 5, 2018 |
CREBBP | 3 | May 2, 2022 |
CRX | 7 | Dec 5, 2018 |
CUL4B | 1 | May 2, 2022 |
DCAF17 | 1 | May 2, 2022 |
DMAP1 | 2 | May 2, 2022 |
DNMT1 | 1 | May 2, 2022 |
DOCK6 | 1 | May 2, 2022 |
DONSON | 1 | May 2, 2022 |
DSPP | 1 | May 2, 2022 |
ECEL1 | 1 | May 2, 2022 |
EDA | 1 | May 2, 2022 |
EHMT1 | 1 | May 2, 2022 |
ELN | 1 | May 2, 2022 |
EPG5 | 2 | May 2, 2022 |
EYS | 28 | Dec 5, 2018 |
FAM161A | 4 | Dec 5, 2018 |
FBXO11 | 2 | May 2, 2022 |
FBXO7 | 1 | May 2, 2022 |
FGD1 | 1 | May 2, 2022 |
FLNA | 2 | May 2, 2022 |
FLVCR1 | 2 | May 2, 2022 |
FOXP1 | 2 | May 2, 2022 |
FRAS1 | 2 | May 2, 2022 |
GAN | 1 | May 2, 2022 |
GDF6 | 1 | May 2, 2022 |
GLI3 | 2 | May 2, 2022 |
GNAS | 1 | May 2, 2022 |
GNAT1 | 1 | Dec 5, 2018 |
GOSR2 | 2 | Feb 16, 2021 |
GPHN | 5 | Dec 5, 2018 |
GPR179 | 2 | Dec 5, 2018 |
GRIN2A | 1 | May 2, 2022 |
GRIN2B | 1 | May 2, 2022 |
GRK1 | 1 | Dec 5, 2018 |
GRM6 | 4 | Dec 5, 2018 |
GUCA1A | 2 | Dec 5, 2018 |
GUCA1ANB-GUCA1A | 2 | Dec 5, 2018 |
GUCY2D | 6 | May 2, 2022 |
H1-4 | 1 | May 2, 2022 |
HARS2 | 5 | May 20, 2019 |
HEXB | 1 | May 2, 2022 |
HMGA2 | 1 | May 2, 2022 |
HNF4A | 1 | May 2, 2022 |
HSPG2 | 2 | May 2, 2022 |
HUWE1 | 1 | May 2, 2022 |
HYCC1 | 1 | May 2, 2022 |
IDH3A | 1 | May 2, 2022 |
IDH3B | 1 | Dec 5, 2018 |
IDUA | 1 | May 2, 2022 |
IGF2 | 1 | May 2, 2022 |
IMPA1 | 1 | May 2, 2022 |
IMPDH1 | 4 | Dec 5, 2018 |
IMPG2 | 3 | Dec 5, 2018 |
INS-IGF2 | 1 | May 2, 2022 |
IQCB1 | 2 | Dec 5, 2018 |
IRF2BPL | 1 | May 2, 2022 |
JMJD8 | 1 | May 2, 2022 |
KARS1 | 2 | May 2, 2022 |
KAT6B | 1 | May 2, 2022 |
KCNT2 | 1 | May 2, 2022 |
KCNV2 | 2 | Dec 5, 2018 |
KDM5C | 1 | May 2, 2022 |
KDM6A | 1 | May 2, 2022 |
KIF11 | 1 | May 2, 2022 |
KMT2A | 3 | May 2, 2022 |
KMT2B | 1 | May 2, 2022 |
KMT2C | 1 | May 2, 2022 |
KMT2D | 1 | May 2, 2022 |
KMT5B | 1 | May 2, 2022 |
LAMP2 | 1 | May 2, 2022 |
LETM1 | 1 | May 2, 2022 |
LINS1 | 1 | May 2, 2022 |
LOC100506235 | 1 | May 2, 2022 |
LOC101927157 | 3 | Dec 5, 2018 |
LOC111828517 | 1 | Dec 5, 2018 |
LOC121740638 | 1 | May 2, 2022 |
LOC122152296 | 1 | Dec 5, 2018 |
LOC126805793 | 10 | Dec 5, 2018 |
LOC126805794 | 1 | Dec 5, 2018 |
LOC126807125 | 1 | May 2, 2022 |
LOC126860392 | 1 | Dec 5, 2018 |
LOC126860736 | 1 | May 2, 2022 |
LOC126861242 | 1 | May 2, 2022 |
LOC126861520 | 1 | May 2, 2022 |
LOC126862571 | 15 | May 27, 2024 |
LOC126862578 | 1 | Feb 16, 2021 |
LOC130003079 | 1 | May 2, 2022 |
LOC130062794 | 1 | May 2, 2022 |
LOC130068098 | 1 | Dec 5, 2018 |
LOC130068202 | 2 | Dec 5, 2018 |
LOX | 2 | May 2, 2022 |
LRAT | 1 | Dec 5, 2018 |
LRRC37A2 | 2 | Feb 16, 2021 |
MAK | 2 | Dec 5, 2018 |
MAN1B1 | 1 | May 2, 2022 |
MAST1 | 1 | May 2, 2022 |
MCOLN1 | 2 | May 2, 2022 |
MEA1 | 1 | May 2, 2022 |
MECP2 | 1 | May 2, 2022 |
MED13L | 1 | May 2, 2022 |
MERTK | 8 | Dec 5, 2018 |
MKKS | 3 | Dec 5, 2018 |
MKS1 | 2 | Dec 5, 2018 |
MMP13 | 1 | May 2, 2022 |
MRPL39 | 1 | Mar 24, 2022 |
MSH2 | 2 | May 27, 2024 |
MSX2 | 1 | May 2, 2022 |
MT-TE | 1 | Jan 13, 2021 |
MYCN | 1 | May 2, 2022 |
MYCNOS | 1 | May 2, 2022 |
MYH3 | 2 | May 2, 2022 |
MYLK | 1 | Jun 22, 2023 |
MYO7A | 7 | Dec 5, 2018 |
NAA15 | 1 | May 2, 2022 |
NDUFA8 | 2 | May 2, 2022 |
NDUFV1 | 2 | May 2, 2022 |
NEB | 1 | May 2, 2022 |
NOD2 | 1 | May 2, 2022 |
NONO | 1 | May 2, 2022 |
NOTCH2 | 1 | Jan 22, 2019 |
NPHP1 | 1 | May 2, 2022 |
NPHP3 | 1 | May 2, 2022 |
NPHP3-ACAD11 | 1 | May 2, 2022 |
NPHP3-AS1 | 1 | May 2, 2022 |
NR2E3 | 7 | Dec 5, 2018 |
NSD2 | 1 | May 2, 2022 |
OTOA | 1 | May 2, 2022 |
PACS2 | 1 | May 2, 2022 |
PBX1 | 1 | May 2, 2022 |
PCARE | 3 | Dec 5, 2018 |
PCDH12 | 1 | May 2, 2022 |
PCDH15 | 2 | Dec 5, 2018 |
PDE6A | 9 | Dec 5, 2018 |
PDE6B | 11 | Dec 5, 2018 |
PDE6B-AS1 | 1 | Dec 5, 2018 |
PDGFB | 1 | May 2, 2022 |
PHF3 | 4 | Dec 5, 2018 |
PIK3CA | 1 | May 2, 2022 |
PIK3R1 | 2 | Jun 13, 2022 |
PITPNM3 | 2 | Dec 5, 2018 |
PMS2 | 2 | May 27, 2024 |
POLR2F | 7 | May 5, 2021 |
POLR3H | 1 | May 2, 2022 |
POU3F3 | 1 | Oct 27, 2022 |
PPP1R12A | 1 | May 2, 2022 |
PPP2CA | 1 | May 2, 2022 |
PPP2R5D | 1 | May 2, 2022 |
PRMT7 | 1 | May 2, 2022 |
PROM1 | 6 | Dec 5, 2018 |
PRPF31 | 15 | Dec 5, 2018 |
PRPF31-AS1 | 5 | Dec 5, 2018 |
PRPF8 | 1 | Dec 5, 2018 |
PRPH2 | 18 | Dec 5, 2018 |
PSMD12 | 1 | May 2, 2022 |
PTEN | 1 | Jun 22, 2023 |
PTPN11 | 1 | May 2, 2022 |
PURA | 1 | May 2, 2022 |
RAB28 | 1 | Dec 5, 2018 |
RAB39B | 1 | May 2, 2022 |
RAI1 | 3 | May 2, 2022 |
RDH12 | 5 | Dec 5, 2018 |
RDH5 | 1 | Dec 5, 2018 |
RGS9 | 1 | Dec 5, 2018 |
RHO | 13 | Dec 5, 2018 |
RIF1 | 1 | May 2, 2022 |
RLBP1 | 1 | Dec 5, 2018 |
RNF14 | 1 | May 2, 2022 |
ROM1 | 1 | Dec 5, 2018 |
ROR2 | 2 | May 2, 2022 |
RP1 | 15 | Dec 5, 2018 |
RP2 | 6 | Dec 5, 2018 |
RPE65 | 4 | Dec 5, 2018 |
RPGR | 13 | Dec 5, 2018 |
RPGRIP1 | 1 | Dec 5, 2018 |
RYR1 | 1 | May 2, 2022 |
SACS | 1 | May 2, 2022 |
SAG | 1 | Dec 5, 2018 |
SALL1 | 3 | May 2, 2022 |
SASS6 | 1 | May 2, 2022 |
SC5D | 2 | May 2, 2022 |
SCN8A | 1 | May 2, 2022 |
SCUBE3 | 1 | May 2, 2022 |
SETD2 | 1 | May 2, 2022 |
SETD5 | 3 | May 2, 2022 |
SKI | 1 | May 2, 2022 |
SLC25A46 | 2 | May 2, 2022 |
SLC34A1 | 1 | May 2, 2022 |
SLC39A8 | 2 | May 2, 2022 |
SLC52A2 | 1 | May 2, 2022 |
SMC1A | 1 | May 2, 2022 |
SMOC2 | 1 | May 2, 2022 |
SNHG14 | 1 | May 2, 2022 |
SNRNP200 | 2 | Dec 5, 2018 |
SOX10 | 7 | May 5, 2021 |
SOX2 | 1 | May 2, 2022 |
SOX2-OT | 1 | May 2, 2022 |
SOX3 | 1 | Oct 16, 2017 |
SPTAN1 | 1 | May 2, 2022 |
SRFBP1 | 2 | May 2, 2022 |
ST3GAL5 | 1 | May 2, 2022 |
STIL | 2 | May 2, 2022 |
STIM1 | 1 | May 2, 2022 |
STRA6 | 1 | May 2, 2022 |
STUB1 | 1 | May 2, 2022 |
SZT2 | 1 | May 2, 2022 |
TAF1 | 1 | May 2, 2022 |
TAFAZZIN | 1 | May 2, 2022 |
TARS2 | 9 | May 2, 2022 |
TBL1XR1 | 1 | May 2, 2022 |
TCF20 | 2 | May 2, 2022 |
TCF4 | 2 | May 2, 2022 |
TFAP2A | 1 | May 2, 2022 |
TFAP2A-AS2 | 1 | May 2, 2022 |
TOPORS | 2 | Dec 5, 2018 |
TP53 | 1 | Oct 27, 2023 |
TRAF7 | 1 | May 2, 2022 |
TRIO | 3 | May 2, 2022 |
TRPM1 | 2 | Dec 5, 2018 |
TSC2 | 2 | May 2, 2022 |
TTC8 | 3 | Dec 5, 2018 |
TUBB2B | 1 | May 2, 2022 |
TUBB3 | 1 | May 2, 2022 |
TULP1 | 3 | Dec 5, 2018 |
TWNK | 1 | May 2, 2022 |
TXNL4A | 2 | May 2, 2022 |
UBAP1 | 1 | May 2, 2022 |
UBE3A | 1 | May 2, 2022 |
UGT1A | 2 | May 2, 2022 |
UGT1A1 | 2 | May 2, 2022 |
UGT1A10 | 2 | May 2, 2022 |
UGT1A3 | 2 | May 2, 2022 |
UGT1A4 | 2 | May 2, 2022 |
UGT1A5 | 2 | May 2, 2022 |
UGT1A6 | 2 | May 2, 2022 |
UGT1A7 | 2 | May 2, 2022 |
UGT1A8 | 2 | May 2, 2022 |
UGT1A9 | 2 | May 2, 2022 |
USH1C | 1 | Dec 5, 2018 |
USH2A | 55 | Oct 25, 2021 |
USH2A-AS1 | 3 | Dec 5, 2018 |
USH2A-AS2 | 7 | Dec 5, 2018 |
VLDLR | 1 | May 2, 2022 |
WAC | 1 | May 2, 2022 |
WDR26 | 1 | May 2, 2022 |
WDR62 | 2 | May 2, 2022 |
WHRN | 1 | Dec 5, 2018 |
YARS1 | 1 | May 2, 2022 |
YY1 | 1 | May 2, 2022 |
YY1AP1 | 1 | May 2, 2022 |
ZBTB18 | 1 | May 2, 2022 |
ZDHHC24 | 8 | Dec 5, 2018 |
ZEB2 | 1 | Sep 1, 2023 |
ZFYVE26 | 1 | Dec 5, 2018 |
ZMYND11 | 1 | May 2, 2022 |
ZNF142 | 2 | May 2, 2022 |
ZNF41 | 1 | May 2, 2022 |
ZNF454 | 2 | Dec 5, 2018 |
ZNF469 | 1 | May 2, 2022 |
Condition
Testing in GTR
Disease name | Number of tests |
---|---|
11p partial monosomy syndrome | 1 test |
6-Pyruvoyl-tetrahydrobiopterin synthase deficiency | 1 test |
Aniridia 1 | 2 tests |
Anophthalmia-microphthalmia syndrome | 1 test |
Anophthalmia/microphthalmia-esophageal atresia syndrome | 1 test |
Anterior segment anomalies with or without cataract | 1 test |
Anterior segment dysgenesis 1 | 2 tests |
Autosomal dominant optic atrophy classic form | 1 test |
Autosomal recessive DOPA responsive dystonia | 1 test |
Axenfeld-Rieger syndrome | 1 test |
Axenfeld-Rieger syndrome type 1 | 3 tests |
Axenfeld-Rieger syndrome type 3 | 3 tests |
Beckwith-Wiedemann syndrome | 1 test |
Brain small vessel disease 1 with or without ocular anomalies | 2 tests |
Branchiooculofacial syndrome | 1 test |
Cataract 23 | 1 test |
Cornea plana 2 | 1 test |
Cornelia de Lange syndrome 1 | 1 test |
Cornelia de Lange syndrome 3 | 1 test |
Cornelia de Lange syndrome 4 | 1 test |
Cornelia de Lange syndrome 5 | 1 test |
Dihydropteridine reductase deficiency | 1 test |
Dopa-responsive dystonia due to sepiapterin reductase deficiency | 1 test |
Early-onset generalized limb-onset dystonia | 1 test |
Focal dermal hypoplasia | 2 tests |
Focal segmental glomerulosclerosis 7 | 1 test |
Frontonasal dysplasia - severe microphthalmia - severe facial clefting syndrome | 1 test |
GTP cyclohydrolase I deficiency | 1 test |
Glaucoma 1, open angle, A | 1 test |
Glaucoma 3A | 1 test |
Intellectual disability, X-linked, with or without seizures, arx-related | 1 test |
Irido-corneo-trabecular dysgenesis | 2 tests |
Leber congenital amaurosis 2 | 1 test |
Linear skin defects with multiple congenital anomalies 1 | 1 test |
Menkes kinky-hair syndrome | 1 test |
Nance-Horan syndrome | 1 test |
Oculocutaneous albinism | 1 test |
Oculocutaneous albinism type 1 | 2 tests |
Oculocutaneous albinism type 1B | 1 test |
Oculocutaneous albinism type 3 | 2 tests |
Oculocutaneous albinism type 4 | 2 tests |
Oculocutaneous albinism type 5 | 1 test |
Oculocutaneous albinism type 6 | 1 test |
Oculocutaneous albinism type 7 | 1 test |
Oculotrichoanal syndrome | 1 test |
Optic atrophy | 1 test |
Optic atrophy with or without deafness, ophthalmoplegia, myopathy, ataxia, and neuropathy | 1 test |
Pallister-Hall syndrome | 1 test |
Peters plus syndrome | 2 tests |
Phenylketonuria | 1 test |
Pierson syndrome | 1 test |
Primary Open Angle Glaucoma (Adult Onset) | 1 test |
Russell-Silver syndrome | 1 test |
Silver-Russell syndrome 1 | 2 tests |
Silver-Russell syndrome due to an imprinting defect of 11p15 | 1 test |
Syndromic microphthalmia | 1 test |
Syndromic microphthalmia type 5 | 1 test |
Torsion dystonia 6 | 1 test |
Tuberous sclerosis 1 | 1 test |
Tuberous sclerosis 2 | 1 test |
Tyrosinase-negative oculocutaneous albinism | 1 test |
Tyrosinase-positive oculocutaneous albinism | 2 tests |
West syndrome | 1 test |
Wilson disease | 1 test |
X-linked lissencephaly with abnormal genitalia | 1 test |