Cancer Variant Interpretation Group UK (Institute of Cancer Research, London), CanVIG-UK
General information
Cancer Variant Interpretation Group UK, CanVIG-UK
Institute of Cancer Research, London
Cotswold Rd
London
Surrey
United Kingdom - SM2 5RG
https://www.icr.ac.uk/
Organization ID: 506655
Institute of Cancer Research, London
Cotswold Rd
London
Surrey
United Kingdom - SM2 5RG
https://www.icr.ac.uk/
Organization ID: 506655
Personnel
- Laura King, Contact
Phone: 00442087224487
Email: CanVIG@icr.ac.uk - Clare Turnbull, Medical Director
Phone: 0044-208-722-4487
Email: clare.turnbull@icr.ac.uk
Assertion criteria
Level: Assertion criteria provided
Summary of submissions to ClinVar
Total submissions: 100
Gene
| Gene | Submissions | Last Updated |
|---|---|---|
| APC | 3 | Jun 26, 2023 |
| ATM | 1 | Jun 26, 2023 |
| BMPR1A | 1 | Mar 16, 2020 |
| BRCA1 | 15 | Jun 21, 2023 |
| BRCA2 | 39 | Jan 17, 2024 |
| C11orf65 | 1 | Jun 26, 2023 |
| CDH1 | 1 | Jun 21, 2023 |
| CHEK2 | 1 | Jun 21, 2023 |
| LOC126862571 | 1 | Oct 31, 2018 |
| MLH1 | 6 | Jun 21, 2023 |
| MSH2 | 4 | Dec 9, 2022 |
| PALB2 | 1 | Jun 26, 2023 |
| PTEN | 7 | Feb 8, 2023 |
| RUNX1 | 1 | Jun 21, 2023 |
| SDHA | 1 | Aug 10, 2020 |
| SDHB | 5 | May 19, 2022 |
| SDHD | 1 | May 19, 2022 |
| TP53 | 13 | Dec 9, 2022 |
Condition
| Name | Submissions | Last Updated |
|---|---|---|
| Ataxia-telangiectasia syndrome | 1 | Jun 26, 2023 |
| Breast-ovarian cancer, familial, susceptibility to, 1 | 1 | Jun 21, 2023 |
| Cowden syndrome | 4 | Nov 26, 2020 |
| Familial adenomatous polyposis 1 | 2 | Mar 16, 2020 |
| Hereditary breast ovarian cancer syndrome | 53 | Jan 17, 2024 |
| Hereditary cancer-predisposing syndrome | 5 | Jun 26, 2023 |
| Hereditary diffuse gastric adenocarcinoma | 1 | Jun 21, 2023 |
| Hereditary nonpolyposis colon cancer | 6 | Nov 26, 2020 |
| Hereditary nonpolyposis colorectal neoplasms | 2 | Dec 9, 2022 |
| Hereditary thrombocytopenia and hematological cancer predisposition syndrome associated with RUNX1 | 1 | Jun 21, 2023 |
| Juvenile Polyposis | 1 | Mar 16, 2020 |
| Li-Fraumeni syndrome | 11 | Mar 22, 2021 |
| Lynch syndrome | 2 | Jun 21, 2023 |
| PTEN hamartoma tumor syndrome | 3 | Feb 8, 2023 |
| Paraganglioma | 6 | May 19, 2022 |
| Pheochromocytoma | 3 | May 19, 2022 |