ClinVar Genomic variation as it relates to human health
GRCh37/hg19 Yp11.32-11.2(chrY:10701-5080415)x2
Germline
Classification
(1)
Pathogenic
no assertion criteria provided
Somatic
No data submitted for somatic clinical impact
Somatic
No data submitted for oncogenicity
Genes
Gene | OMIM | ClinGen Gene Dosage Sensitivity Curation | Variation Viewer | Related variants | ||
---|---|---|---|---|---|---|
HI score | TS score | Within gene | All | |||
SRY | Sufficient evidence for dosage pathogenicity | No evidence available |
GRCh38 GRCh37 |
59 | 125 | |
PCDH11Y | - | - |
GRCh38 GRCh37 |
2 | 69 | |
RPS4Y1 | - | - |
GRCh38 GRCh37 |
- | 67 | |
TGIF2LY | - | - |
GRCh38 GRCh37 |
5 | 72 | |
ZFY | - | - |
GRCh38 GRCh37 |
- | 64 |
Conditions - Germline
Condition | Classification
(# of submissions) |
Review status | Last evaluated | Variation/condition record |
---|---|---|---|---|
See cases
|
Pathogenic (1) |
|
Feb 17, 2021 | RCV001353181.1 |
Citations for germline classification of this variant
HelpText-mined citations for this variant ...
HelpRecord last updated Apr 25, 2022