ClinVar Genomic variation as it relates to human health
NM_004985.5(KRAS):c.141T>C (p.Asp47=)
Germline
Classification
(2)
Likely benign
criteria provided, multiple submitters, no conflicts
Somatic
No data submitted for somatic clinical impact
Somatic
No data submitted for oncogenicity
Genes
Gene | OMIM | ClinGen Gene Dosage Sensitivity Curation | Variation Viewer | Related variants | ||
---|---|---|---|---|---|---|
HI score | TS score | Within gene | All | |||
KRAS | No evidence available | No evidence available |
GRCh38 GRCh37 |
463 | 521 |
Conditions - Germline
Condition | Classification
(# of submissions) |
Review status | Last evaluated | Variation/condition record |
---|---|---|---|---|
Likely benign (1) |
|
May 20, 2022 | RCV003075449.3 | |
Likely benign (1) |
|
Aug 2, 2023 | RCV003367981.2 |
Citations for germline classification of this variant
HelpText-mined citations for this variant ...
HelpRecord last updated Sep 29, 2024