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Links from MedGen

Items: 15

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
TMEM147, TMEM147-AS1
(Q46P)
Single nucleotide variant
(non-coding transcript variant +2 more)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GUncertain significance
TMEM147, TMEM147-AS1
(A11P)
Single nucleotide variant
(5 prime UTR variant +1 more)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GUncertain significance
TMEM147
(T55fs +1 more)
Deletion
(frameshift variant)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147, TMEM147-AS1
(G7R)
Single nucleotide variant
(5 prime UTR variant +1 more)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
+2 more
GConflicting classifications of pathogenicity
TMEM147
(F57fs +1 more)
Microsatellite
(frameshift variant)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147
(Y113* +2 more)
Single nucleotide variant
(nonsense)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147
(R117W +2 more)
Single nucleotide variant
(missense variant)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147
(V108fs +2 more)
Duplication
(frameshift variant)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147
(W130* +1 more)
Single nucleotide variant
(nonsense +1 more)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147
Single nucleotide variant
(splice acceptor variant +1 more)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147
Single nucleotide variant
(intron variant)
Motor delay
+4 more
GPathogenic
TMEM147
(I133N +1 more)
Single nucleotide variant
(missense variant +1 more)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147, TMEM147-AS1
(Y21*)
Single nucleotide variant
(5 prime UTR variant +1 more)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147
(N140fs +1 more)
Duplication
(frameshift variant +1 more)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147, TMEM147-AS1
(K34fs)
Deletion
(5 prime UTR variant +1 more)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
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