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Links from MedGen

Items: 40

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
WAPL
(R668C +1 more)
Single nucleotide variant
(missense variant)
Polyhydramnios
+5 more
GUncertain significance
CUL9
(P911L)
Single nucleotide variant
(missense variant)
Intellectual disability, moderate
+14 more
GUncertain significance
CUL9
(R2413W)
Single nucleotide variant
(missense variant)
Intellectual disability, moderate
+14 more
GUncertain significance
FOXP4
(A501T +2 more)
Single nucleotide variant
(missense variant)
Disproportionate short stature
+8 more
GPathogenic/Likely pathogenic
FBN2
(T2555A)
Single nucleotide variant
(missense variant)
Global developmental delay
+6 more
GUncertain significance
COL1A2
Single nucleotide variant
(intron variant)
Decreased body weight
+9 more
GConflicting classifications of pathogenicity
ASXL3
(E452K)
Single nucleotide variant
(missense variant)
Ventricular septal defect
+2 more
GUncertain significance
DPH2, LOC126805726
(R125C +4 more)
Single nucleotide variant
(missense variant +1 more)
Ventricular septal defect
+3 more
GConflicting classifications of pathogenicity
DPH2, LOC126805726
(Q115* +5 more)
Single nucleotide variant
(nonsense +1 more)
Ventricular septal defect
+3 more
GConflicting classifications of pathogenicity
LRP1
(S4520C)
Single nucleotide variant
(missense variant)
Tricuspid atresia
+1 more
GUncertain significance
LRP1
(L526V)
Single nucleotide variant
(missense variant)
Tricuspid atresia
+1 more
GUncertain significance
SMARCA4
(R967H)
Single nucleotide variant
(missense variant +1 more)
not provided
+2 more
GConflicting classifications of pathogenicity
IGLC1, BCR
+5 more
Copy number loss
Ventricular septal defect
+2 more
GPathogenic
LRRK1, ASB7
+3 more
Copy number loss
Esophageal atresia
+3 more
GUncertain significance
APBA2, ATP10A
+32 more
Complex
Seizure
+3 more
GPathogenic
NSD2
(E1099K)
Single nucleotide variant
(missense variant)
Neurodevelopmental delay
+14 more
GConflicting classifications of pathogenicity
FLNA
(R1312C)
Single nucleotide variant
(missense variant)
Oto-palato-digital syndrome, type II
+6 more
GConflicting classifications of pathogenicity
GATA4
(A32P)
Single nucleotide variant
(missense variant +1 more)
Atrial septal defect
+11 more
GUncertain significance
ERF
(R546* +1 more)
Single nucleotide variant
(nonsense)
Atrial septal defect
+11 more
GUncertain significance
OBSL1
(W1114*)
Single nucleotide variant
(nonsense)
Coarctation of aorta
+12 more
GUncertain significance
OBSL1
(R994C)
Single nucleotide variant
(missense variant)
Coarctation of aorta
+12 more
GUncertain significance
HUWE1
(R2162P)
Single nucleotide variant
(missense variant)
Blepharophimosis
+7 more
GUncertain significance
MYCN
(P409L +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+4 more
GUncertain significance
FLVCR2
Copy number loss
Ventriculomegaly
+6 more
GUncertain significance
TBX5
(Y407* +1 more)
Single nucleotide variant
(nonsense)
Ventricular septal defect
+2 more
GPathogenic
RPS6KA3
(A178G)
Single nucleotide variant
(missense variant)
Abnormality of the lower limb
+13 more
GLikely pathogenic
FOXF1
(N94Y)
Single nucleotide variant
(missense variant)
Alveolar capillary dysplasia with pulmonary venous misalignment
+3 more
GLikely pathogenic
SMARCA4
(T453I)
Single nucleotide variant
(missense variant +1 more)
Intellectual disability, autosomal dominant 16
+6 more
GConflicting classifications of pathogenicity
Translocation
Premature eruption of permanent teeth
+6 more
GPathogenic
Inversion
Involuntary movements
+3 more
GUncertain significance
Translocation
Ventricular septal defect
+3 more
GUncertain significance
Translocation
Penile hypospadias
+6 more
GUncertain significance
Translocation
Corpus callosum, agenesis of
+24 more
GUncertain significance
Complex
Piebaldism
+15 more
GUncertain significance
Translocation
Atrial septal defect
+10 more
GUncertain significance
AAR2
(V174M)
Single nucleotide variant
(missense variant)
Microcephaly
+7 more
GLikely pathogenic
FOXP4
(L270fs +2 more)
Deletion
(frameshift variant)
Laryngeal hypoplasia
+3 more
GLikely pathogenic
ACOT6, ACYP1
+59 more
Deletion
Multiple skeletal anomalies
+3 more
GLikely pathogenic
RYR1
(E2764K)
Single nucleotide variant
(missense variant)
Malignant hyperthermia of anesthesia
GUncertain significanceFDA Recognized
database
BRAF
(E501G +7 more)
Single nucleotide variant
(missense variant)
Cardio-facio-cutaneous syndrome
+13 more
GPathogenic/Likely pathogenic
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