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Links from MedGen

Items: 23

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
PIK3CA
Single nucleotide variant
(splice donor variant)
CLOVES syndrome
GLikely pathogenic
PIK3R1
Indel
(inframe_indel)
CLOVES syndrome
GLikely pathogenic
PIK3R1
Deletion
(inframe_deletion)
Vascular Malformations and Overgrowth
+1 more
GPathogenic/Likely pathogenic
PIK3R1
(K204E +3 more)
Single nucleotide variant
(missense variant)
CLOVES syndrome
GLikely pathogenic
PIK3CA
(E110del)
Microsatellite
(inframe_deletion)
Overgrowth syndrome and/or cerebral malformations due to abnormalities in MTOR pathway genes
GLikely pathogenic
PIK3CA
(C378R)
Single nucleotide variant
(missense variant)
Megalencephaly-capillary malformation-polymicrogyria syndrome
+1 more
GPathogenic
GNA11
(R183C)
Single nucleotide variant
(missense variant)
Capillary malformation
+3 more
GPathogenic
PIK3CA
(V146I)
Single nucleotide variant
(missense variant)
Familial cancer of breast
+14 more
GUncertain significance
PIK3CA
(K884R)
Single nucleotide variant
(missense variant)
not specified
+16 more
GUncertain significance
PIK3CA
(P377R)
Single nucleotide variant
(missense variant)
Cowden syndrome
+14 more
GUncertain significance
PIK3CA
(G106V)
Single nucleotide variant
(missense variant)
CLOVES syndrome
+2 more
GConflicting classifications of pathogenicity
PIK3CA
(E81K)
Single nucleotide variant
(missense variant)
not provided
+3 more
GPathogenic
PIK3CA
(E453K)
Single nucleotide variant
(missense variant)
PIK3CA-related disorder
+5 more
GPathogenic
PIK3CA
(N345K)
Single nucleotide variant
(missense variant)
Congenital macrodactylia
+14 more
GPathogenic
PIK3CA
(R88Q)
Single nucleotide variant
(missense variant)
Megalencephaly-capillary malformation-polymicrogyria syndrome
+5 more
GPathogenic
OOncogenic
PIK3CA
(T1025A)
Single nucleotide variant
(missense variant)
Non-small cell lung carcinoma
+2 more
GPathogenic/Likely pathogenic
PIK3CA
(E418K)
Single nucleotide variant
(missense variant)
PIK3CA related overgrowth syndrome
+2 more
GConflicting classifications of pathogenicity
OLikely oncogenic
PIK3CA
(H1047Y)
Single nucleotide variant
(missense variant)
Segmental undergrowth associated with mainly venous malformation with capillary component
+18 more
GPathogenic
PIK3CA
(C420R)
Single nucleotide variant
(missense variant)
Cowden syndrome
+7 more
GPathogenic
OOncogenic
PIK3CA
(E542K)
Single nucleotide variant
(missense variant)
Overgrowth syndrome and/or cerebral malformations due to abnormalities in MTOR pathway genes
+1 more
GPathogenic
OOncogenic
PIK3CA
(E545K)
Single nucleotide variant
(missense variant)
Eccrine angiomatous hamartoma
+6 more
GPathogenic/Likely pathogenic
OOncogenic
PIK3CA
(H1047L)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+8 more
GPathogenic
OOncogenic
PIK3CA
(H1047R)
Single nucleotide variant
(missense variant)
Overgrowth syndrome and/or cerebral malformations due to abnormalities in MTOR pathway genes
+1 more
GPathogenic
OOncogenic
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