GEO DataSets

(Submitter supplied) DNA replication initiates from defined locations called replication origins; some origins are highly active whereas others are dormant and rarely used. Origins also differ in their activation time resulting in particular genomic regions replicating at characteristic times and in a defined temporal order. Here we report the comparison of genome replication in four budding yeast species: Saccharomyces cerevisiae, S. more...

Organism:

Saccharomyces bayanus; Saccharomyces arboricola; Saccharomyces paradoxus; Saccharomyces bayanus x Saccharomyces cerevisiae; Saccharomyces cerevisiae

Type:

Genome variation profiling by high throughput sequencing

5 related Platforms

10 Samples

Download data: FA, TXT, WIG

(Submitter supplied) We assess the prevalence of polygenic evolution in pathways between the yeasts S. cerevisiae and S. bayanus. We first established short-read sequencing methods to detect cis-regulatory variation in a diploid hybrid between the species. We then formulated an analytic strategy to test for the scenario in which selective pressure in one species, to increase or decrease the activity of a pathway, has driven the accumulation of cis-regulatory variants that act in the same direction on gene expression. more...

Organism:

Saccharomyces bayanus x Saccharomyces cerevisiae

Type:

Expression profiling by high throughput sequencing

Platform:

GPL10079

8 Samples

Download data: TXT