GEO DataSets

Analysis of the DHL4 and DHL6 diffuse large B-cell lymphoma (DLBCL) cell lines following treatment with R406, a spleen tyrosine kinase (SYK) inhibitor. SYK is a key component of BCR signaling which is a critical pathway in DLBCL. Results provide insight into the role of SYK in DLBCL pathogenesis.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 agent, 2 cell line, 5 time sets

Platform:

GPL3921

Series:

GSE34176

29 Samples

Download data: CEL

Analysis of AML cell lines infected with shRNAs against glycogen synthase kinase 3 α and β isoforms (GSK-3α, GSK-3β). GSK-3 is a multifunctional serine threonine kinase; specific loss of GSK-3α induces differentiation in AML. Results provide insight into the role of GSK-3α in AML.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 4 cell line, 3 genotype/variation, 5 other sets

Platform:

GPL3921

Series:

GSE35200

44 Samples

Download data: CEL

Analysis of HBECs treated with IFNβ, wild-type H1N1 influenza (PR8), mutant ΔNS1 virus (PR8 with a deleted NS1 gene), viral RNA (purified directly from PR8), up to 18 hr post-treatment. Results provide insight into the molecular mechanisms mediating influenza-host interactions in H1N1 infection.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 11 agent, 7 dose, 11 time sets

Platform:

GPL3921

Series:

GSE19392

169 Samples

Download data: CEL

Analysis of Hepatocellular carcinoma (HCC) Huh-7 cells stimulated with transforming growth factor-beta (TGF-β). HCC cell line Huh-7 has intact WNT pathway components. Results provide insight into the role of TGF-β in regulating WNT pathway activity in HCC cells.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL3921

Series:

GSE10393

4 Samples

Download data: CEL