GEO DataSets

(Submitter supplied) Endocrine disrupting chemicals (EDCs) are compounds that disrupt normal hormonal signaling. Examples are Xenoestrogens (e.g BPA) and Phytoestrogens (e.g isoflavones).

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL15127

6 Samples

Download data: GPR

(Submitter supplied) This submission is a part of two separate studies: a study of estrogen receptor-alpha (ERalpha)-mediated gene expression in response to different ligands and a study examining the roles of ERalpha and ERbeta in gene regulation in breast cancer cells.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL15127

2 Samples

Download data: GPR

(Submitter supplied) Comparison of the basal and estrogen-induced effects on genome-wide transcription in ERα-positive breast cancer cell lines T47D and MCF7 after lentiviral transduction with ERβ.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL15127

8 Samples

Download data: GPR

(Submitter supplied) The estrogen receptor (ER)β1 is successively lost during cancer progression, whereas its splice variant, ERβ2, is expressed in advanced prostate cancer. The latter form of cancer often metastasizes to bone, and we wanted to investigate whether the loss of ERβ1 and/or the expression of ERβ2 affect such signaling pathways in prostate cancer. Using PC3 and 22Rv1 prostate cancer cell lines that stably express ERβ1 or ERβ2, we found that the ERβ variants differentially regulate genes known to affect tumor behavior. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL15127

10 Samples

Download data: GPR

(Submitter supplied) See manufacturer's website at http://www.microarrays.com/dna-arrays.php

Organism:

Homo sapiens

4 Series

26 Samples

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