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Items: 1 to 20 of 74

1.

Dual RNA-seq – Dual RNA-seq of further sRNA mutants

(Submitter supplied) Bacteria possess many small noncoding RNAs whose regulatory roles in pathogenesis are little understood due to a paucity of macroscopic phenotypes in standard virulence assays. Here, we use a novel Dual RNA-seq approach for a single-step simultaneous RNA profiling in both pathogen and host to reveal molecular phenotypes of sRNAs during infection with Salmonella Typhimurium. We identify a new PhoP/Q-activated small RNA which upon bacterial internalization acts to temporally control the expression of both, invasion-associated effectors and virulence genes required for intracellular survival. more...
Organism:
Homo sapiens; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL20051 GPL20050
42 Samples
Download data: CSV
Series
Accession:
GSE67952
ID:
200067952

PubMed Similar studies SRA Run Selector

2.

Dual RNA-seq – Host response to pinT*

(Submitter supplied) Bacteria possess many small noncoding RNAs whose regulatory roles in pathogenesis are little understood due to a paucity of macroscopic phenotypes in standard virulence assays. Here, we use a novel Dual RNA-seq approach for a single-step simultaneous RNA profiling in both pathogen and host to reveal molecular phenotypes of sRNAs during infection with Salmonella Typhimurium. We identify a new PhoP/Q-activated small RNA which upon bacterial internalization acts to temporally control the expression of both, invasion-associated effectors and virulence genes required for intracellular survival. more...
Organism:
Homo sapiens; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20050
8 Samples
Download data: CSV
Series
Accession:
GSE67951
ID:
200067951

PubMed Similar studies SRA Run Selector

3.

Dual RNA-seq – Pulse-expression of pinT

(Submitter supplied) Bacteria possess many small noncoding RNAs whose regulatory roles in pathogenesis are little understood due to a paucity of macroscopic phenotypes in standard virulence assays. Here, we use a novel Dual RNA-seq approach for a single-step simultaneous RNA profiling in both pathogen and host to reveal molecular phenotypes of sRNAs during infection with Salmonella Typhimurium. We identify a new PhoP/Q-activated small RNA which upon bacterial internalization acts to temporally control the expression of both, invasion-associated effectors and virulence genes required for intracellular survival. more...
Organism:
Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344; Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL20062 GPL20050
12 Samples
Download data: CSV
Series
Accession:
GSE67950
ID:
200067950

PubMed Similar studies SRA Run Selector

4.

Dual RNA-seq – sRNA profiling in various cell types

(Submitter supplied) Bacteria possess many small noncoding RNAs whose regulatory roles in pathogenesis are little understood due to a paucity of macroscopic phenotypes in standard virulence assays. Here, we use a novel Dual RNA-seq approach for a single-step simultaneous RNA profiling in both pathogen and host to reveal molecular phenotypes of sRNAs during infection with Salmonella Typhimurium. We identify a new PhoP/Q-activated small RNA which upon bacterial internalization acts to temporally control the expression of both, invasion-associated effectors and virulence genes required for intracellular survival. more...
Organism:
Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344; Homo sapiens; Sus scrofa; Mus musculus
Type:
Expression profiling by high throughput sequencing
6 related Platforms
89 Samples
Download data: CSV
Series
Accession:
GSE67947
ID:
200067947

PubMed Similar studies SRA Run Selector

5.

Dual RNA-seq – Pilot Dual RNA-seq

(Submitter supplied) Bacteria possess many small noncoding RNAs whose regulatory roles in pathogenesis are little understood due to a paucity of macroscopic phenotypes in standard virulence assays. Here, we use a novel Dual RNA-seq approach for a single-step simultaneous RNA profiling in both pathogen and host to reveal molecular phenotypes of sRNAs during infection with Salmonella Typhimurium. We identify a new PhoP/Q-activated small RNA which upon bacterial internalization acts to temporally control the expression of both, invasion-associated effectors and virulence genes required for intracellular survival. more...
Organism:
Homo sapiens; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20050
24 Samples
Download data: CSV
Series
Accession:
GSE67757
ID:
200067757

PubMed Similar studies SRA Run Selector

6.

Dual RNA-seq of diverse human, mouse and pig cell-types infected with various Salmonella strains

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Salmonella enterica subsp. enterica serovar Typhimurium; Homo sapiens; Sus scrofa; Mus musculus; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344
Type:
Expression profiling by high throughput sequencing
8 related Platforms
279 Samples
Download data
Series
Accession:
GSE60144
ID:
200060144

PubMed Similar studies

7.

Illumina HiSeq 2000 (Homo sapiens; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344)

Organism:
Homo sapiens; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344
6 Series
67 Samples
Download data
Platform
Accession:
GPL20050
ID:
100020050

8.

16 h mock replicate 2

Organism:
Homo sapiens; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344
Source name:
cell culture infection model
Platform:
GPL20050
Series:
GSE60144 GSE67952
Download data
Sample
Accession:
GSM1967963
ID:
301967963

SRA Run Selector

9.

16 h mock replicate 1

Organism:
Homo sapiens; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344
Source name:
cell culture infection model
Platform:
GPL20050
Series:
GSE60144 GSE67952
Download data
Sample
Accession:
GSM1967962
ID:
301967962

SRA Run Selector

10.

4 h mock replicate 2

Organism:
Homo sapiens; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344
Source name:
cell culture infection model
Platform:
GPL20050
Series:
GSE60144 GSE67952
Download data
Sample
Accession:
GSM1967960
ID:
301967960

SRA Run Selector

11.

4 h mock replicate 1

Organism:
Homo sapiens; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344
Source name:
cell culture infection model
Platform:
GPL20050
Series:
GSE60144 GSE67952
Download data
Sample
Accession:
GSM1967959
ID:
301967959

SRA Run Selector

12.

16 h WT replicate 2

Organism:
Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344; Homo sapiens
Source name:
cell culture infection model
Platform:
GPL20050
Series:
GSE60144 GSE67952
Download data
Sample
Accession:
GSM1967957
ID:
301967957

SRA Run Selector

13.

16 h WT replicate 1

Organism:
Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344; Homo sapiens
Source name:
cell culture infection model
Platform:
GPL20050
Series:
GSE60144 GSE67952
Download data
Sample
Accession:
GSM1967956
ID:
301967956

SRA Run Selector

14.

4 h WT replicate 2

Organism:
Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344; Homo sapiens
Source name:
cell culture infection model
Platform:
GPL20050
Series:
GSE60144 GSE67952
Download data
Sample
Accession:
GSM1967954
ID:
301967954

SRA Run Selector

15.

4 h WT replicate 1

Organism:
Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344; Homo sapiens
Source name:
cell culture infection model
Platform:
GPL20050
Series:
GSE60144 GSE67952
Download data
Sample
Accession:
GSM1967953
ID:
301967953

SRA Run Selector

16.

0 h WT replicate 2

Organism:
Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344; Homo sapiens
Source name:
cell culture infection model
Platform:
GPL20050
Series:
GSE60144 GSE67952
Download data
Sample
Accession:
GSM1967951
ID:
301967951

SRA Run Selector

17.

0 h WT replicate 1

Organism:
Homo sapiens; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344
Source name:
cell culture infection model
Platform:
GPL20050
Series:
GSE60144 GSE67952
Download data
Sample
Accession:
GSM1967950
ID:
301967950

SRA Run Selector

18.

16 h ΔyrlA/B replicate 2

Organism:
Homo sapiens; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344
Source name:
cell culture infection model
Platform:
GPL20050
Series:
GSE60144 GSE67952
Download data
Sample
Accession:
GSM1967948
ID:
301967948

SRA Run Selector

19.

16 h ΔyrlA/B replicate 1

Organism:
Homo sapiens; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344
Source name:
cell culture infection model
Platform:
GPL20050
Series:
GSE60144 GSE67952
Download data
Sample
Accession:
GSM1967947
ID:
301967947

SRA Run Selector

20.

4 h ΔyrlA/B replicate 2

Organism:
Homo sapiens; Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344
Source name:
cell culture infection model
Platform:
GPL20050
Series:
GSE60144 GSE67952
Download data
Sample
Accession:
GSM1967945
ID:
301967945

SRA Run Selector

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