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Items: 2

1.

Evolutionary conservation of the eumetazoan gene regulatory landscape

(Submitter supplied) Bilaterian animals differ from other metazoans in their apparent bilateral symmetry and the development of a third germ layer. Both might have facilitated the evolution of the diverse and complex bilaterian body plans. The first cnidarian genome sequence revealed that despite their morphological simplicity, this sister group to all bilaterians shares an immense genomic complexity with vertebrates. This suggested that it might have been the complexity of gene regulation which increased during the evolution of bilaterians. more...
Organism:
Nematostella vectensis
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL17090 GPL9914
29 Samples
Download data: BED
Series
Accession:
GSE46488
ID:
200046488
2.

Genome-wide evolutionary analysis of eukaryotic DNA methylation

(Submitter supplied) Eukaryotic cytosine methylation represses transposable elements, but also occurs in bodies of active genes. The extent to which these processes are conserved is unclear, and little is known about methylation outside of mammals, Arabidopsis thaliana, and Neurospora crassa. Utilizing deep bisulfite sequencing, we have quantified DNA methylation in five plant, seven animal, and five fungal genomes. We find that gene body methylation is conserved between plants and animals, whereas selective methylation of transposons has evolved independently in the vertebrate lineage. more...
Organism:
Volvox carteri; Coprinopsis cinerea; Bombyx mori; Ciona intestinalis; Tetraodon nigroviridis; Chlorella variabilis; Physcomitrium patens; Phycomyces blakesleeanus; Drosophila melanogaster; Apis mellifera; Laccaria bicolor; Uncinocarpus reesii; Selaginella moellendorffii; Postia placenta; Oryza sativa; Tribolium castaneum; Nematostella vectensis
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
17 related Platforms
33 Samples
Download data: GFF, TXT
Series
Accession:
GSE19824
ID:
200019824

Supplemental Content

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