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Items: 9

1.

Gene expression changes following dihydrotestosterone (DHT) treatment in HCI-009 PDXs

(Submitter supplied) Triple-negative breast cancer (TNBC) is aggressive and difficult, and few targeted therapies are available to treat this patient population. The androgen receptor (AR) has emerged as a potential target in breast cancer. Newer generation AR inhibitors, such as Seviteronel (Sevi), are unique in their ability to inhibit AR both directly and by blocking upstream androgen synthesis. The purpose of this study was to investigate the pre-clinical activity of Sevi in TNBC and further explore the effectiveness of targeting both androgen biosynthesis and AR activity in combination with other downstream acting agents. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
7 Samples
Download data: XLSX
Series
Accession:
GSE152246
ID:
200152246

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
15884 Series
909013 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

3.

DHT PDX HCI-009 3942

Organism:
Homo sapiens
Source name:
Patient derived xenograft tumors
Platform:
GPL24676
Series:
GSE152246
Download data
Sample
Accession:
GSM4609856
ID:
304609856

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4.

DHT PDX HCI-009 3941

Organism:
Homo sapiens
Source name:
Patient derived xenograft tumors
Platform:
GPL24676
Series:
GSE152246
Download data
Sample
Accession:
GSM4609855
ID:
304609855

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5.

DHT PDX HCI-009 3940

Organism:
Homo sapiens
Source name:
Patient derived xenograft tumors
Platform:
GPL24676
Series:
GSE152246
Download data
Sample
Accession:
GSM4609854
ID:
304609854

SRA Run Selector

6.

DHT PDX HCI-009 3939

Organism:
Homo sapiens
Source name:
Patient derived xenograft tumors
Platform:
GPL24676
Series:
GSE152246
Download data
Sample
Accession:
GSM4609853
ID:
304609853

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7.

Ctrl PDX HCI-009 3946

Organism:
Homo sapiens
Source name:
Patient derived xenograft tumors
Platform:
GPL24676
Series:
GSE152246
Download data
Sample
Accession:
GSM4609852
ID:
304609852

SRA Run Selector

8.

Ctrl PDX HCI-009 3944

Organism:
Homo sapiens
Source name:
Patient derived xenograft tumors
Platform:
GPL24676
Series:
GSE152246
Download data
Sample
Accession:
GSM4609851
ID:
304609851

SRA Run Selector

9.

Ctrl PDX HCI-009 3943

Organism:
Homo sapiens
Source name:
Patient derived xenograft tumors
Platform:
GPL24676
Series:
GSE152246
Download data
Sample
Accession:
GSM4609850
ID:
304609850

SRA Run Selector

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db=gds|term=GSE152246[Accession]|query=1|qty=2|blobid=MCID_66c8b8f1c8112916c0ddf44c|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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