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Items: 1 to 20 of 21

1.

C-peptide and/or transforming growth factor beta 1 effect on human proximal tubular cell line

(Submitter supplied) Microarray analysis reveals up-regulation of retinoic acid and hepatocyte growth factor related signaling pathways by pro-insulin C-peptide in kidney proximal tubular cells: Antagonism of the pro-fibrotic effects of TGF-b1 Novel signaling roles for C-peptide have recently been discovered with evidence that it can ameliorate complications of type 1 diabetes. Here we sought to identify new pathways regulated by C-peptide of relevance to the pathophysiology of diabetic nephropathy. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3649
Platform:
GPL6884
18 Samples
Download data: TXT
Series
Accession:
GSE20247
ID:
200020247

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.
Full record GDS3649

Proinsulin C-peptide and TGF-beta 1 effect on proximal tubular cell line: time course

Analysis of HK2 proximal tubular cells (PTCs) treated with C-peptide, TBF-beta 1, or both agents for 18 or 48 hours. C-peptide alleviates TGF-beta 1-mediated phenotypic and morphological changes in PTCs associated with epithelial-mesenchymal transformation (EMT). EMT contributes to renal fibrosis.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 agent, 2 time sets
Platform:
GPL6884
Series:
GSE20247
18 Samples
Download data
DataSet
Accession:
GDS3649
ID:
3649

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

3.

Illumina HumanWG-6 v3.0 expression beadchip

(Submitter supplied) The HumanWG-6 v3.0 Expression BeadChip features up-to-date content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36.2, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. These should be submitted as part of a GEOarchive. more...
Organism:
Homo sapiens
9 DataSets
324 Series
9525 Samples
Download data: BGX
Platform
Accession:
GPL6884
ID:
100006884

4.

TGF-beta_C-peptide_48hrs_rep3

Organism:
Homo sapiens
Source name:
HK-2 cells
Platform:
GPL6884
Series:
GSE20247
Dataset:
GDS3649
Download data
Sample
Accession:
GSM507431
ID:
300507431

5.

TGF-beta_C-peptide_48hrs_rep2

Organism:
Homo sapiens
Source name:
HK-2 cells
Platform:
GPL6884
Series:
GSE20247
Dataset:
GDS3649
Download data
Sample
Accession:
GSM507430
ID:
300507430

6.

TGF-beta_C-peptide_48hrs_rep1

Organism:
Homo sapiens
Source name:
HK-2 cells
Platform:
GPL6884
Series:
GSE20247
Dataset:
GDS3649
Download data
Sample
Accession:
GSM507429
ID:
300507429

7.

C-peptide_18hrs_rep3

Organism:
Homo sapiens
Source name:
HK-2 cells
Platform:
GPL6884
Series:
GSE20247
Dataset:
GDS3649
Download data
Sample
Accession:
GSM507428
ID:
300507428

8.

C-peptide_18hrs_rep2

Organism:
Homo sapiens
Source name:
HK-2 cells
Platform:
GPL6884
Series:
GSE20247
Dataset:
GDS3649
Download data
Sample
Accession:
GSM507427
ID:
300507427

9.

C-peptide_18hrs_rep1

Organism:
Homo sapiens
Source name:
HK-2 cells
Platform:
GPL6884
Series:
GSE20247
Dataset:
GDS3649
Download data
Sample
Accession:
GSM507426
ID:
300507426

10.

C-peptide_48hrs_rep3

Organism:
Homo sapiens
Source name:
HK-2 cells
Platform:
GPL6884
Series:
GSE20247
Dataset:
GDS3649
Download data
Sample
Accession:
GSM507425
ID:
300507425

11.

C-peptide_48hrs_rep2

Organism:
Homo sapiens
Source name:
HK-2 cells
Platform:
GPL6884
Series:
GSE20247
Dataset:
GDS3649
Download data
Sample
Accession:
GSM507424
ID:
300507424

12.

C-peptide_48hrs_rep1

Organism:
Homo sapiens
Source name:
HK-2 cells
Platform:
GPL6884
Series:
GSE20247
Dataset:
GDS3649
Download data
Sample
Accession:
GSM507423
ID:
300507423

13.

TGF-beta_48hrs_rep3

Organism:
Homo sapiens
Source name:
HK-2 cells
Platform:
GPL6884
Series:
GSE20247
Dataset:
GDS3649
Download data
Sample
Accession:
GSM507422
ID:
300507422

14.

TGF-beta_48hrs_rep2

Organism:
Homo sapiens
Source name:
HK-2 cells
Platform:
GPL6884
Series:
GSE20247
Dataset:
GDS3649
Download data
Sample
Accession:
GSM507421
ID:
300507421

15.

TGF-beta_48hrs_rep1

Organism:
Homo sapiens
Source name:
HK-2 cells
Platform:
GPL6884
Series:
GSE20247
Dataset:
GDS3649
Download data
Sample
Accession:
GSM507420
ID:
300507420

16.

Control_18hrs_rep3

Organism:
Homo sapiens
Source name:
HK-2 cells
Platform:
GPL6884
Series:
GSE20247
Dataset:
GDS3649
Download data
Sample
Accession:
GSM507419
ID:
300507419

17.

Control_18hrs_rep2

Organism:
Homo sapiens
Source name:
HK-2 cells
Platform:
GPL6884
Series:
GSE20247
Dataset:
GDS3649
Download data
Sample
Accession:
GSM507418
ID:
300507418

18.

Control_18hrs_rep1

Organism:
Homo sapiens
Source name:
HK-2 cells
Platform:
GPL6884
Series:
GSE20247
Dataset:
GDS3649
Download data
Sample
Accession:
GSM507417
ID:
300507417

19.

Control_48hrs_rep3

Organism:
Homo sapiens
Source name:
HK-2 cells
Platform:
GPL6884
Series:
GSE20247
Dataset:
GDS3649
Download data
Sample
Accession:
GSM507416
ID:
300507416

20.

Control_48hrs_rep2

Organism:
Homo sapiens
Source name:
HK-2 cells
Platform:
GPL6884
Series:
GSE20247
Dataset:
GDS3649
Download data
Sample
Accession:
GSM507415
ID:
300507415

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