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Items: 8

1.

MUC1-C INDUCES PBRM1-MEDIATED CHROMATIN REMODELING IN DRIVING CHRONIC INFLAMMATION AND DNA DAMAGE RESISTANCE IN TRIPLE-NEGATIVE BREAST CANCER [tet-MUC1 shRNA]

(Submitter supplied) STAT1 and IRF1 are essential effectors of the type I and II interferon (IFN) pathways. Here, we report that the oncogenic MUC1-C protein is necessary for inducing chromatin accessibility and activation of the STAT1 and IRF1 genes in triple-negative breast cancer (TNBC) cells. Our results demonstrate that MUC1-C activates the PBRM1 subunit of the SWI/SNF PBAF chromatin remodeling complex and forms a nuclear complex with PBRM1. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
6 Samples
Download data: CSV
Series
Accession:
GSE212587
ID:
200212587

PubMed Full text in PMC Similar studies

2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
16422 Series
921197 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

3.

MDA-MB-436_shMUC1_3

Organism:
Homo sapiens
Source name:
Cell Line
Platform:
GPL24676
Series:
GSE212170 GSE212587
Download data
Sample
Accession:
GSM6538025
ID:
306538025

SRA Run Selector

4.

MDA-MB-436_shMUC1_2

Organism:
Homo sapiens
Source name:
Cell Line
Platform:
GPL24676
Series:
GSE212170 GSE212587
Download data
Sample
Accession:
GSM6538024
ID:
306538024

SRA Run Selector

5.

MDA-MB-436_shMUC1_1

Organism:
Homo sapiens
Source name:
Cell Line
Platform:
GPL24676
Series:
GSE212170 GSE212587
Download data
Sample
Accession:
GSM6538023
ID:
306538023

SRA Run Selector

6.

MDA-MB-436_control_shRNA_3

Organism:
Homo sapiens
Source name:
Cell Line
Platform:
GPL24676
Series:
GSE212170 GSE212587
Download data
Sample
Accession:
GSM6538022
ID:
306538022

SRA Run Selector

7.

MDA-MB-436_control_shRNA_2

Organism:
Homo sapiens
Source name:
Cell Line
Platform:
GPL24676
Series:
GSE212170 GSE212587
Download data
Sample
Accession:
GSM6538021
ID:
306538021

SRA Run Selector

8.

MDA-MB-436_control_shRNA_1

Organism:
Homo sapiens
Source name:
Cell Line
Platform:
GPL24676
Series:
GSE212170 GSE212587
Download data
Sample
Accession:
GSM6538020
ID:
306538020

SRA Run Selector

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