GSE234742[Accession] - GEO DataSets - NCBI

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Items: 4

Select item 2002347421.

The Protective Role of Integrin α4β7 and Amphiregulin-Expressing Innate Lymphoid Cells in Lupus Nephritis

(Submitter supplied) Type-2 innate lymphoid cells (ILC2s) have emerged as key immune-response regulators in renal-inflammatory diseases such as lupus nephritis. However, the adhesion and migration of ILC2s, including in the homeostatic and diseased kidney, are poorly understood. By integrating transcriptomic profiling, flow cytometry, live-cell imaging, and in-vivo models, we showed that renal ILCs are retained in the homeostatic kidney by the adherence of their cell-surface integrin α4β7 to VCAM-1, E-cadherin or fibronectin on structural kidney cells. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24247
2 Samples

Download data: MTX, TSV

Series

Accession:: GSE234742

ID:: 200234742

Select item 1000242472.

Illumina NovaSeq 6000 (Mus musculus)

Organism:: Mus musculus

12252 Series
665235 Samples

Platform

Accession:: GPL24247

ID:: 100024247

Select item 3074741813.

Young MRL-lpr kidney

Organism:: Mus musculus

Source name:: Kidney

Platform:: GPL24247
Series:: GSE234742

Download data: MTX, TSV

Sample

Accession:: GSM7474181

ID:: 307474181

SRA Run Selector

Select item 3074741804.

Old MRL-lpr kidney

Organism:: Mus musculus

Source name:: Kidney

Platform:: GPL24247
Series:: GSE234742

Download data: MTX, TSV

Sample

Accession:: GSM7474180

ID:: 307474180

SRA Run Selector

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GSE234742[Accession] (4)
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