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Items: 1 to 20 of 45

1.

Citrulline supplementation leads to increased immune suppression and more severe outcomes in infected newborn piglets

(Submitter supplied) Background: Preterm infants are at high risk of infection and sepsis, which is associated with arginine (ARG) deficiency. Optimal nutrition for preterm newborns suspected with infection is critical to prevent sepsis development. Citrulline (CIT) supplementation is known to prevent sepsis in adult rodents, by maintaining sufficient blood ARG levels and vascular stabilization. We hypothesized that CIT therapy improve sepsis outcomes in infected preterm newborns via CIT and ARG metabolism.Results: After infection, oral CIT supplementation led to higher mortality, blood bacterial load, and circulating and hepatic inflammation, compared with the infected controls. more...
Organism:
Sus scrofa
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26351
43 Samples
Download data: XLS
Series
Accession:
GSE247865
ID:
200247865
2.

Illumina NovaSeq 6000 (Sus scrofa)

Platform
Accession:
GPL26351
ID:
100026351
3.

Infection, ORA_CIT, Liver12

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901815
ID:
307901815
4.

Infection, ORA_CIT, Liver11

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901814
ID:
307901814
5.

Infection, ORA_CIT, Liver10

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901813
ID:
307901813
6.

Infection, ORA_CIT, Liver9

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901812
ID:
307901812
7.

Infection, ORA_CIT, Liver8

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901811
ID:
307901811
8.

Infection, ORA_CIT, Liver7

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901810
ID:
307901810
9.

Infection, ORA_CIT, Liver6

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901809
ID:
307901809
10.

Infection, ORA_CIT, Liver5

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901808
ID:
307901808
11.

Infection, ORA_CIT, Liver4

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901807
ID:
307901807
12.

Infection, ORA_CIT, Liver3

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901806
ID:
307901806
13.

Infection, ORA_CIT, Liver2

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901805
ID:
307901805
14.

Infection, ORA_CIT, Liver1

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901804
ID:
307901804
15.

Infection, IV_CIT, Liver11

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901803
ID:
307901803
16.

Infection, IV_CIT, Liver10

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901802
ID:
307901802
17.

Infection, IV_CIT, Liver9

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901801
ID:
307901801
18.

Infection, IV_CIT, Liver8

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901800
ID:
307901800
19.

Infection, IV_CIT, Liver7

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901799
ID:
307901799
20.

Infection, IV_CIT, Liver6

Organism:
Sus scrofa
Source name:
Liver
Platform:
GPL26351
Series:
GSE247865
Download data
Sample
Accession:
GSM7901798
ID:
307901798
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Supplemental Content

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