GSE33622[Accession] - GEO DataSets

Select item 2000336221.

Expression data from human iPS cells treated by a small molecule KY02111

(Submitter supplied) Human pluripotent stem cells (hPSCs) such as embryonic stem cells and induced pluripotent stem cells are promising materials for cell-based regenerative therapies to heart diseases. However, until realization there are many hurdles such as high efficiency of cardiac differentiation of hPSCs and production of clinical-grade cardiac cells derived from hPSCs. Here, we show that a novel small molecule KY02111 robustly enhances differentiation to functional cardiomyocytes from hPSCs. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4322
Platform:: GPL6244
5 Samples

Download data: CEL, TXT

Series

Accession:: GSE33622

ID:: 200033622

Select item 43222.

Small molecule KY02111 effect on induced pluripotent stem cell line IMR90-1: time course

Analysis of IMR90-1 iPSCs cultured in cardiac differentiation medium containing serum for 3 days, then treated with KY02111 for up to 24 hrs. KY02111 promotes differentiation of PSCs to cardiomyocytes. Results provide insight into molecular basis of KY02111-induced cardiac differentiation of PSCs.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent, 3 time sets

Platform:: GPL6244
Series:: GSE33622
5 Samples

Download data: CEL

DataSet

Accession:: GDS4322

ID:: 4322

Select item 1000062443.

[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 18, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site