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Items: 14

1.

Effect of IRE1a and XBP1 knockdown on gene expression in primary mouse keratinocytes expressing an HRas oncogene

(Submitter supplied) IRE1a is a critical modulator of the unfolded protein response. Its RNAse activity generates the mature transcript for the XBP1 transcription factor and also degrades other ER associated mRNAs in a process termed Regulated IRE1a Dependent mRNA Decay or RIDD. To determine if IRE1a is critical in the response to oncogenic Ras we used ShRNA to knockdown Ire1a or Xbp1 in primary mouse epidermal keratinocytes transduced with a v-HRAS retrovirus.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL16570
12 Samples
Download data: CEL
Series
Accession:
GSE70899
ID:
200070899

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Jan 30, 2013: annotation table updated with netaffx build 33 Protocol: See manufacturer's web site
Organism:
Mus musculus
1094 Series
7 Related Platforms
11078 Samples
Download data
Platform
Accession:
GPL16570
ID:
100016570

3.

v-Hras transduced mouse epidermal keratinocytes + Xbp1 ShRNA lentivirus biol replicate 3

Organism:
Mus musculus
Source name:
primary mouse epidermal keratinocyte
Platform:
GPL16570
Series:
GSE70899
Download data: CEL
Sample
Accession:
GSM1821462
ID:
301821462

4.

v-Hras transduced mouse epidermal keratinocytes + Xbp1 ShRNA lentivirus biol replicate 2

Organism:
Mus musculus
Source name:
primary mouse epidermal keratinocyte
Platform:
GPL16570
Series:
GSE70899
Download data: CEL
Sample
Accession:
GSM1821461
ID:
301821461

5.

v-Hras transduced mouse epidermal keratinocytes + Xbp1 ShRNA lentivirus biol replicate 1

Organism:
Mus musculus
Source name:
primary mouse epidermal keratinocyte
Platform:
GPL16570
Series:
GSE70899
Download data: CEL
Sample
Accession:
GSM1821460
ID:
301821460

6.

v-Hras transduced mouse epidermal keratinocytes + Ire1a ShRNA lentivirus biol replicate 3

Organism:
Mus musculus
Source name:
primary mouse epidermal keratinocyte
Platform:
GPL16570
Series:
GSE70899
Download data: CEL
Sample
Accession:
GSM1821459
ID:
301821459

7.

v-Hras transduced mouse epidermal keratinocytes + Ire1a ShRNA lentivirus biol replicate 2

Organism:
Mus musculus
Source name:
primary mouse epidermal keratinocyte
Platform:
GPL16570
Series:
GSE70899
Download data: CEL
Sample
Accession:
GSM1821458
ID:
301821458

8.

v-Hras transduced mouse epidermal keratinocytes + Ire1a ShRNA lentivirus biol replicate 1

Organism:
Mus musculus
Source name:
primary mouse epidermal keratinocyte
Platform:
GPL16570
Series:
GSE70899
Download data: CEL
Sample
Accession:
GSM1821457
ID:
301821457

9.

v-Hras transduced mouse epidermal keratinocytes + control ShRNA lentivirus biol replicate 3

Organism:
Mus musculus
Source name:
primary mouse epidermal keratinocyte
Platform:
GPL16570
Series:
GSE70899
Download data: CEL
Sample
Accession:
GSM1821456
ID:
301821456

10.

v-Hras transduced mouse epidermal keratinocytes + control ShRNA lentivirus biol replicate 2

Organism:
Mus musculus
Source name:
primary mouse epidermal keratinocyte
Platform:
GPL16570
Series:
GSE70899
Download data: CEL
Sample
Accession:
GSM1821455
ID:
301821455

11.

v-Hras transduced mouse epidermal keratinocytes + control ShRNA lentivirus biol replicate 1

Organism:
Mus musculus
Source name:
primary mouse epidermal keratinocyte
Platform:
GPL16570
Series:
GSE70899
Download data: CEL
Sample
Accession:
GSM1821454
ID:
301821454

12.

Mouse epidermal keratinocytes + control ShRNA lentivirus biol replicate 3

Organism:
Mus musculus
Source name:
primary mouse epidermal keratinocyte
Platform:
GPL16570
Series:
GSE70899
Download data: CEL
Sample
Accession:
GSM1821453
ID:
301821453

13.

Mouse epidermal keratinocytes + control ShRNA lentivirus biol replicate 2

Organism:
Mus musculus
Source name:
primary mouse epidermal keratinocyte
Platform:
GPL16570
Series:
GSE70899
Download data: CEL
Sample
Accession:
GSM1821452
ID:
301821452

14.

Mouse epidermal keratinocytes + control ShRNA lentivirus biol replicate 1

Organism:
Mus musculus
Source name:
primary mouse epidermal keratinocyte
Platform:
GPL16570
Series:
GSE70899
Download data: CEL
Sample
Accession:
GSM1821451
ID:
301821451

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